tretinoin-1548 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tretinoin-1548 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACSL1 acyl-CoA synthetase long-chain family member 1
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AHR aryl hydrocarbon receptor
AIM2 absent in melanoma 2
ANGPTL4 angiopoietin-like 4
ARG1 arginase 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
BAG3 BCL2-associated athanogene 3
BCL2A1 BCL2-related protein A1
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCLAF1 BCL2-associated transcription factor 1
C1ORF106 chromosome 1 open reading frame 106
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCR1 chemokine (C-C motif) receptor 1
CD1D CD1d molecule
CD300A CD300a molecule
CD38 CD38 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
COLEC12 collectin sub-family member 12
CREG1 cellular repressor of E1A-stimulated genes 1
CTSB cathepsin B
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
EFNB2 ephrin-B2
EIF1B eukaryotic translation initiation factor 1B
ENAH enabled homolog (Drosophila)
ENDOD1 endonuclease domain containing 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM134B family with sequence similarity 134, member B
FAM13A family with sequence similarity 13, member A
FGR FGR proto-oncogene, Src family tyrosine kinase
G0S2 G0/G1 switch 2
GAS7 growth arrest-specific 7
GCLM glutamate-cysteine ligase, modifier subunit
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPRC5C G protein-coupled receptor, class C, group 5, member C
HBEGF heparin-binding EGF-like growth factor
HCAR3 hydroxycarboxylic acid receptor 3
HOXA5 homeobox A5
HPCAL1 hippocalcin-like 1
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIF leukemia inhibitory factor
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
METTL7A methyltransferase like 7A
MYBPH myosin binding protein H
NCF1C neutrophil cytosolic factor 1C pseudogene
NINJ1 ninjurin 1
NRIP1 nuclear receptor interacting protein 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PDLIM5 PDZ and LIM domain 5
PGD phosphogluconate dehydrogenase
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLCB2 phospholipase C, beta 2
PLEK pleckstrin
PLIN2 perilipin 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POR P450 (cytochrome) oxidoreductase
PPARD peroxisome proliferator-activated receptor delta
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PSAP prosaposin
PTGES prostaglandin E synthase
RAB31 RAB31, member RAS oncogene family
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB3 Rho-related BTB domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLA Src-like-adaptor
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMAD3 SMAD family member 3
SMOX spermine oxidase
SOAT1 sterol O-acyltransferase 1
SQSTM1 sequestosome 1
TBL2 transducin (beta)-like 2
TGM2 transglutaminase 2
TIMP1 TIMP metallopeptidase inhibitor 1
TMEM156 transmembrane protein 156
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TREM1 triggering receptor expressed on myeloid cells 1
TRIB1 tribbles pseudokinase 1
UPB1 ureidopropionase, beta
USF2 upstream transcription factor 2, c-fos interacting
ZEB2 zinc finger E-box binding homeobox 2

decreased expression

Symbol Name
ABT1 activator of basal transcription 1
ADGRA3 adhesion G protein-coupled receptor A3
ADSS adenylosuccinate synthase
AES amino-terminal enhancer of split
ANKRD28 ankyrin repeat domain 28
ANXA6 annexin A6
ARID5B AT rich interactive domain 5B (MRF1-like)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BMS1 BMS1 ribosome biogenesis factor
BTK Bruton agammaglobulinemia tyrosine kinase
BYSL bystin-like
C10ORF2 chromosome 10 open reading frame 2
C12ORF29 chromosome 12 open reading frame 29
CA2 carbonic anhydrase II
CBX6 chromobox homolog 6
CD3EAP CD3e molecule, epsilon associated protein
CD69 CD69 molecule
CEP85 centrosomal protein 85kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC5A C-type lectin domain family 5, member A
COA7 cytochrome c oxidase assembly factor 7 (putative)
CST7 cystatin F (leukocystatin)
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DKC1 dyskeratosis congenita 1, dyskerin
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
E2F6 E2F transcription factor 6
ECD ecdysoneless homolog (Drosophila)
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
FAM173A family with sequence similarity 173, member A
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FOXK2 forkhead box K2
GLRX5 glutaredoxin 5
GMPPB GDP-mannose pyrophosphorylase B
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GPD1L glycerol-3-phosphate dehydrogenase 1-like
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCTD15 potassium channel tetramerization domain containing 15
LAMP5 lysosomal-associated membrane protein family, member 5
LARP1 La ribonucleoprotein domain family, member 1
LAS1L LAS1-like (S. cerevisiae)
LMNB1 lamin B1
MAPK10 mitogen-activated protein kinase 10
METTL9 methyltransferase like 9
MPV17 MpV17 mitochondrial inner membrane protein
MRPS34 mitochondrial ribosomal protein S34
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MTG1 mitochondrial ribosome-associated GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NIP7 NIP7, nucleolar pre-rRNA processing protein
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOL6 nucleolar protein 6 (RNA-associated)
NOL8 nucleolar protein 8
NPM3 nucleophosmin/nucleoplasmin 3
NT5DC2 5'-nucleotidase domain containing 2
NUCLEOLIN nucleolin multifunctional protein
PES1 pescadillo ribosomal biogenesis factor 1
PFAS phosphoribosylformylglycinamidine synthase
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
PPAN peter pan homolog (Drosophila)
PRDM13 PR domain containing 13
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRR3 proline rich 3
PSAT1 phosphoserine aminotransferase 1
PTGES2 prostaglandin E synthase 2
PUS1 pseudouridylate synthase 1
PUS7 pseudouridylate synthase 7 (putative)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
PYCR1 pyrroline-5-carboxylate reductase 1
RABEPK Rab9 effector protein with kelch motifs
RPE ribulose-5-phosphate-3-epimerase
RPIA ribose 5-phosphate isomerase A
RPP40 ribonuclease P/MRP 40kDa subunit
RRP1 ribosomal RNA processing 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RUVBL1 RuvB-like AAA ATPase 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STRA13 stimulated by retinoic acid 13
TARP TCR gamma alternate reading frame protein
TBL3 transducin (beta)-like 3
TERT telomerase reverse transcriptase
TLR2 toll-like receptor 2
TMEM177 transmembrane protein 177
TRAPPC2L trafficking protein particle complex 2-like
TULP4 tubby like protein 4
UBIAD1 UbiA prenyltransferase domain containing 1
UCK2 uridine-cytidine kinase 2
UNG uracil-DNA glycosylase
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
WDR3 WD repeat domain 3
WDR43 WD repeat domain 43
WDR77 WD repeat domain 77