tretinoin-3165 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tretinoin-3165 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AOX1 aldehyde oxidase 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ASTN1 astrotactin 1
BCL3 B-cell CLL/lymphoma 3
BDKRB2 bradykinin receptor B2
BFSP1 beaded filament structural protein 1, filensin
BTF3P11 basic transcription factor 3 pseudogene 11
BTG2 BTG family, member 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL13 chemokine (C-C motif) ligand 13
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK13 cyclin-dependent kinase 13
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDRT1 CMT1A duplicated region transcript 1
CGA glycoprotein hormones, alpha polypeptide
CHAT choline O-acetyltransferase
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLMN calmin (calponin-like, transmembrane)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLX2 distal-less homeobox 2
DLX4 distal-less homeobox 4
DMRT1 doublesex and mab-3 related transcription factor 1
DNAI2 dynein, axonemal, intermediate chain 2
DUSP4 dual specificity phosphatase 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPAS1 endothelial PAS domain protein 1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
FAM174B family with sequence similarity 174, member B
FH fumarate hydratase
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAP43 growth associated protein 43
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GRPR gastrin-releasing peptide receptor
HDAC7 histone deacetylase 7
HIST1H3C histone cluster 1, H3c
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXA5 homeobox A5
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGHA1 immunoglobulin heavy constant alpha 1
IGLV1-44 immunoglobulin lambda variable 1-44
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KIAA0125 KIAA0125
KLHL3 kelch-like family member 3
LAMA3 laminin, alpha 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MUC6 mucin 6, oligomeric mucus/gel-forming
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OSGIN1 oxidative stress induced growth inhibitor 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRB3 proline-rich protein BstNI subfamily 3
PRMT2IP PRMT2 interacting protein
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RECQL5 RecQ protein-like 5
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELL selectin L
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SPTBN2 spectrin, beta, non-erythrocytic 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK17A serine/threonine kinase 17a
STRN striatin, calmodulin binding protein
TDRD12 tudor domain containing 12
TGFBI transforming growth factor, beta-induced, 68kDa
TMPRSS2 transmembrane protease, serine 2
TMPRSS4 transmembrane protease, serine 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRIO trio Rho guanine nucleotide exchange factor
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
VPS9D1 VPS9 domain containing 1
WNT8B wingless-type MMTV integration site family, member 8B
ZNF682 zinc finger protein 682
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
AFAP1 actin filament associated protein 1
AFF4 AF4/FMR2 family, member 4
AKAP12 A kinase (PRKA) anchor protein 12
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANXA1 annexin A1
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BMP4 bone morphogenetic protein 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CCDC69 coiled-coil domain containing 69
CCNE1 cyclin E1
CEP97 centrosomal protein 97kDa
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CISH cytokine inducible SH2-containing protein
COL4A5 collagen, type IV, alpha 5
CST6 cystatin E/M
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMTN dematin actin binding protein
DNAL4 dynein, axonemal, light chain 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGR3 early growth response 3
EIF5A2 eukaryotic translation initiation factor 5A2
FLJ22184
FZD4 frizzled class receptor 4
GBP2 guanylate binding protein 2, interferon-inducible
GHR growth hormone receptor
GLCE glucuronic acid epimerase
GLI3 GLI family zinc finger 3
GPRC5C G protein-coupled receptor, class C, group 5, member C
H2AFJ H2A histone family, member J
HIRA histone cell cycle regulator
HIST1H2AL histone cluster 1, H2al
HOXC5 homeobox C5
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDI2-AS1 IDI2 antisense RNA 1
INCENP inner centromere protein antigens 135/155kDa
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD7 potassium channel tetramerization domain containing 7
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
KIF13A kinesin family member 13A
LDHB lactate dehydrogenase B
LOC100287590 uncharacterized LOC100287590
LYPD3 LY6/PLAUR domain containing 3
LYZ lysozyme
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MISP mitotic spindle positioning
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
NFE2L3 nuclear factor, erythroid 2-like 3
NPY1R neuropeptide Y receptor Y1
NT5E 5'-nucleotidase, ecto (CD73)
NXN nucleoredoxin
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PLA2G15 phospholipase A2, group XV
POLL polymerase (DNA directed), lambda
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAB3A RAB3A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNF126P1 ring finger protein 126 pseudogene 1
SALL2 spalt-like transcription factor 2
SCGB2A2 secretoglobin, family 2A, member 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SDC3 syndecan 3
SKA1 spindle and kinetochore associated complex subunit 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SOCS7 suppressor of cytokine signaling 7
SRGN serglycin
STAG3 stromal antigen 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STBD1 starch binding domain 1
TAOK1 TAO kinase 1
TEAD3 TEA domain family member 3
TET3 tet methylcytosine dioxygenase 3
TMEM120B transmembrane protein 120B
TMEM180 transmembrane protein 180
TNS2 tensin 2
TPST1 tyrosylprotein sulfotransferase 1
TRAF5 TNF receptor-associated factor 5
TRIM5 tripartite motif containing 5
TSPAN5 tetraspanin 5
WDR76 WD repeat domain 76
ZFHX3 zinc finger homeobox 3
ZNF35 zinc finger protein 35
ZNF350 zinc finger protein 350
ZNF675 zinc finger protein 675
ZNF816 zinc finger protein 816