tretinoin-384 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tretinoin-384 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
APOA1 apolipoprotein A-I
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB2 arrestin, beta 2
AXIN1 axin 1
BIK BCL2-interacting killer (apoptosis-inducing)
BMP7 bone morphogenetic protein 7
BRAP BRCA1 associated protein
C20ORF27 chromosome 20 open reading frame 27
CCDC87 coiled-coil domain containing 87
CDC25A cell division cycle 25A
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLDN17 claudin 17
CLMN calmin (calponin-like, transmembrane)
COL6A3 collagen, type VI, alpha 3
COMMD9 COMM domain containing 9
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPD carboxypeptidase D
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYLD cylindromatosis (turban tumor syndrome)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DHPS deoxyhypusine synthase
DHRS3 dehydrogenase/reductase (SDR family) member 3
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EPAS1 endothelial PAS domain protein 1
ESR1 estrogen receptor 1
FANCF Fanconi anemia, complementation group F
FASTK Fas-activated serine/threonine kinase
FN1 fibronectin 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GAS8 growth arrest-specific 8
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GJA5 gap junction protein, alpha 5, 40kDa
GLG1 golgi glycoprotein 1
GLI3 GLI family zinc finger 3
GPR107 G protein-coupled receptor 107
GULP1 GULP, engulfment adaptor PTB domain containing 1
HCAR3 hydroxycarboxylic acid receptor 3
HIRIP3 HIRA interacting protein 3
HIST1H3G histone cluster 1, H3g
HIST1H4J histone cluster 1, H4j
HOXA1 homeobox A1
HOXA5 homeobox A5
HPS1 Hermansky-Pudlak syndrome 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IFITM1 interferon induced transmembrane protein 1
IL15RA interleukin 15 receptor, alpha
LARP4B La ribonucleoprotein domain family, member 4B
LMF2 lipase maturation factor 2
LRP5 low density lipoprotein receptor-related protein 5
MAGOHB mago-nashi homolog B (Drosophila)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK8 mitogen-activated protein kinase 8
MASP2 mannan-binding lectin serine peptidase 2
MAST2 microtubule associated serine/threonine kinase 2
MNAT1 MNAT CDK-activating kinase assembly factor 1
NADK NAD kinase
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NOL6 nucleolar protein 6 (RNA-associated)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
ORC4 origin recognition complex, subunit 4
OXLD1 oxidoreductase-like domain containing 1
PAIP2B poly(A) binding protein interacting protein 2B
PBX1 pre-B-cell leukemia homeobox 1
PCGF1 polycomb group ring finger 1
PCTP phosphatidylcholine transfer protein
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PEX14 peroxisomal biogenesis factor 14
PHLDA1 pleckstrin homology-like domain, family A, member 1
POU5F1B POU class 5 homeobox 1B
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRRC2B proline-rich coiled-coil 2B
RAI14 retinoic acid induced 14
RECQL5 RecQ protein-like 5
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SHB Src homology 2 domain containing adaptor protein B
SKAP2 src kinase associated phosphoprotein 2
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SMAD3 SMAD family member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNX10 sorting nexin 10
SOX9 SRY (sex determining region Y)-box 9
SZRD1 SUZ RNA binding domain containing 1
TJP3 tight junction protein 3
TMEM70 transmembrane protein 70
TMPRSS2 transmembrane protease, serine 2
TMSB4Y thymosin beta 4, Y-linked
TOB2 transducer of ERBB2, 2
TRAFD1 TRAF-type zinc finger domain containing 1
VPS33B vacuolar protein sorting 33 homolog B (yeast)
VRK3 vaccinia related kinase 3
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADRA2B adrenoceptor alpha 2B
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMN amnion associated transmembrane protein
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ASAP1-IT1 ASAP1 intronic transcript 1
ATXN3L ataxin 3-like
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C14ORF79 chromosome 14 open reading frame 79
C22ORF29 chromosome 22 open reading frame 29
CCDC7 coiled-coil domain containing 7
CCL11 chemokine (C-C motif) ligand 11
CD5 CD5 molecule
CHGB chromogranin B
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLCN2 chloride channel, voltage-sensitive 2
CNTD2 cyclin N-terminal domain containing 2
CRYAB crystallin, alpha B
DAGLA diacylglycerol lipase, alpha
DOC2A double C2-like domains, alpha
DRP2 dystrophin related protein 2
DUSP13 dual specificity phosphatase 13
EGR3 early growth response 3
EPN3 epsin 3
EXOC2 exocyst complex component 2
FAM188A family with sequence similarity 188, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FOXD1 forkhead box D1
GALR3 galanin receptor 3
GPA33 glycoprotein A33 (transmembrane)
GPR87 G protein-coupled receptor 87
GSTA4 glutathione S-transferase alpha 4
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HAND1 heart and neural crest derivatives expressed 1
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
HOXB1 homeobox B1
HPGDS hematopoietic prostaglandin D synthase
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI35 interferon-induced protein 35
IL10RA interleukin 10 receptor, alpha
IL22 interleukin 22
INA internexin neuronal intermediate filament protein, alpha
INO80D INO80 complex subunit D
IREB2 iron-responsive element binding protein 2
IRF2 interferon regulatory factor 2
IRF8 interferon regulatory factor 8
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLHL36 kelch-like family member 36
LCT lactase
LEFTY1 left-right determination factor 1
LEMD3 LEM domain containing 3
LGALS13 lectin, galactoside-binding, soluble, 13
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LY86 lymphocyte antigen 86
MAOB monoamine oxidase B
MED31 mediator complex subunit 31
MFGE8 milk fat globule-EGF factor 8 protein
MICB MHC class I polypeptide-related sequence B
MIR22HG MIR22 host gene
MYL1 myosin, light chain 1, alkali; skeletal, fast
NLRP2 NLR family, pyrin domain containing 2
NPR3 natriuretic peptide receptor 3
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PCP4 Purkinje cell protein 4
PER3 period circadian clock 3
PGC progastricsin (pepsinogen C)
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHOX2B paired-like homeobox 2b
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PON3 paraoxonase 3
RASL11B RAS-like, family 11, member B
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIN1 Ras and Rab interactor 1
SCIN scinderin
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC46A3 solute carrier family 46, member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPRYD7 SPRY domain containing 7
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SYNDIG1 synapse differentiation inducing 1
TBC1D16 TBC1 domain family, member 16
TCP10L t-complex 10-like
TGFBR1 transforming growth factor, beta receptor 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TP53I3 tumor protein p53 inducible protein 3
UBQLN3 ubiquilin 3
VASP vasodilator-stimulated phosphoprotein
ZBTB11 zinc finger and BTB domain containing 11
ZBTB39 zinc finger and BTB domain containing 39
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF184 zinc finger protein 184
ZNF562 zinc finger protein 562