tretinoin-4435 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the tretinoin-4435 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACVR1B activin A receptor, type IB
ADAP1 ArfGAP with dual PH domains 1
ADRA1D adrenoceptor alpha 1D
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANGPTL4 angiopoietin-like 4
APC2 adenomatosis polyposis coli 2
ASPA aspartoacylase
BGN biglycan
C10ORF10 chromosome 10 open reading frame 10
C22ORF31 chromosome 22 open reading frame 31
C3AR1 complement component 3a receptor 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC82 coiled-coil domain containing 82
CCR1 chemokine (C-C motif) receptor 1
CD1E CD1e molecule
CDC14B cell division cycle 14B
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHRDL1 chordin-like 1
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CNPY4 canopy FGF signaling regulator 4
CPZ carboxypeptidase Z
CSF1R colony stimulating factor 1 receptor
CST1 cystatin SN
CTF1 cardiotrophin 1
DIO3 deiodinase, iodothyronine, type III
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUSP1 dual specificity phosphatase 1
ELL elongation factor RNA polymerase II
ERN1 endoplasmic reticulum to nucleus signaling 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FASLG Fas ligand (TNF superfamily, member 6)
FBXO40 F-box protein 40
FGF4 fibroblast growth factor 4
FLT1 fms-related tyrosine kinase 1
FXYD2 FXYD domain containing ion transport regulator 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLI2 GLI family zinc finger 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPM6B glycoprotein M6B
GPR85 G protein-coupled receptor 85
HIST3H3 histone cluster 3, H3
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ICAM1 intercellular adhesion molecule 1
IGHA1 immunoglobulin heavy constant alpha 1
KLHL18 kelch-like family member 18
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LAMA4 laminin, alpha 4
LEF1 lymphoid enhancer-binding factor 1
LIMD1 LIM domains containing 1
LINC00312 long intergenic non-protein coding RNA 312
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK11 mitogen-activated protein kinase 11
MBD2 methyl-CpG binding domain protein 2
MFSD7 major facilitator superfamily domain containing 7
MOBP myelin-associated oligodendrocyte basic protein
MOGAT2 monoacylglycerol O-acyltransferase 2
MORN1 MORN repeat containing 1
MYH14 myosin, heavy chain 14, non-muscle
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
N4BP2L1 NEDD4 binding protein 2-like 1
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NRL neural retina leucine zipper
OSBPL7 oxysterol binding protein-like 7
PAX3 paired box 3
PER2 period circadian clock 2
PHOX2A paired-like homeobox 2a
PKD2L2 polycystic kidney disease 2-like 2
PLCH2 phospholipase C, eta 2
PPP5C protein phosphatase 5, catalytic subunit
PRLH prolactin releasing hormone
PTCRA pre T-cell antigen receptor alpha
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM34 RNA binding motif protein 34
REEP2 receptor accessory protein 2
RGS12 regulator of G-protein signaling 12
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SSTR3 somatostatin receptor 3
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TM4SF4 transmembrane 4 L six family member 4
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMPRSS5 transmembrane protease, serine 5
TRAPPC9 trafficking protein particle complex 9
TRPM8 transient receptor potential cation channel, subfamily M, member 8
UCN urocortin
VNN2 vanin 2
YBX2 Y box binding protein 2
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
AKTIP AKT interacting protein
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BMP4 bone morphogenetic protein 4
C16ORF59 chromosome 16 open reading frame 59
C1QTNF3 C1q and tumor necrosis factor related protein 3
CAMKMT calmodulin-lysine N-methyltransferase
CCDC186 coiled-coil domain containing 186
CDK6 cyclin-dependent kinase 6
CFAP45 cilia and flagella associated protein 45
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNTLN centlein, centrosomal protein
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP8 dual specificity phosphatase 8
EDAR ectodysplasin A receptor
EN1 engrailed homeobox 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM155A family with sequence similarity 155, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FRK fyn-related Src family tyrosine kinase
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAB2 GRB2-associated binding protein 2
GLB1L2 galactosidase, beta 1-like 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRAMD1C GRAM domain containing 1C
GREB1L growth regulation by estrogen in breast cancer-like
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC11 histone deacetylase 11
HINFP histone H4 transcription factor
HIST1H1E histone cluster 1, H1e
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HOXA7 homeobox A7
HOXB2 homeobox B2
HSPA1L heat shock 70kDa protein 1-like
IL12RB1 interleukin 12 receptor, beta 1
IL22 interleukin 22
IL6 interleukin 6
INF2 inverted formin, FH2 and WH2 domain containing
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1549L KIAA1549-like
KIRREL kin of IRRE like (Drosophila)
KLHL28 kelch-like family member 28
LMTK1 lemur tail kinase 1
MMP13 matrix metallopeptidase 13
MMRN2 multimerin 2
MST1 macrophage stimulating 1
MTA2 metastasis associated 1 family, member 2
MUC3B mucin 3B, cell surface associated
MYH15 myosin, heavy chain 15
NCALD neurocalcin delta
NEUROD4 neuronal differentiation 4
NKX3-2 NK3 homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP6 poly (ADP-ribose) polymerase family, member 6
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLA1A phospholipase A1 member A
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PQLC2 PQ loop repeat containing 2
PRAMEF11 PRAME family member 11
PRB3 proline-rich protein BstNI subfamily 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RWDD2A RWD domain containing 2A
SCGB2A2 secretoglobin, family 2A, member 2
SCIN scinderin
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC22A14 solute carrier family 22, member 14
SLMO1 slowmo homolog 1 (Drosophila)
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMO smoothened, frizzled class receptor
SNRPN small nuclear ribonucleoprotein polypeptide N
SOSTDC1 sclerostin domain containing 1
STAG3 stromal antigen 3
STON1 stonin 1
STX17 syntaxin 17
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
THRB thyroid hormone receptor, beta
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
UGT8 UDP glycosyltransferase 8
WDR25 WD repeat domain 25
ZNF214 zinc finger protein 214
ZNF222 zinc finger protein 222
ZNF267 zinc finger protein 267