| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tretinoin-447 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACAN | aggrecan |
| ADA | adenosine deaminase |
| AGTR2 | angiotensin II receptor, type 2 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOC1 | apolipoprotein C-I |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| AVPR1B | arginine vasopressin receptor 1B |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CA7 | carbonic anhydrase VII |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAPN5 | calpain 5 |
| CCDC71 | coiled-coil domain containing 71 |
| CLDN17 | claudin 17 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| COL1A2 | collagen, type I, alpha 2 |
| COL5A1 | collagen, type V, alpha 1 |
| CORO1B | coronin, actin binding protein, 1B |
| CORT | cortistatin |
| CTSE | cathepsin E |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DOK3 | docking protein 3 |
| DPP6 | dipeptidyl-peptidase 6 |
| DRG2 | developmentally regulated GTP binding protein 2 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EPX | eosinophil peroxidase |
| ERCC5 | excision repair cross-complementation group 5 |
| EXOC7 | exocyst complex component 7 |
| FUS | FUS RNA binding protein |
| GALR3 | galanin receptor 3 |
| GPM6B | glycoprotein M6B |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRK6 | G protein-coupled receptor kinase 6 |
| GSK3A | glycogen synthase kinase 3 alpha |
| H2AFY2 | H2A histone family, member Y2 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IFFO1 | intermediate filament family orphan 1 |
| INO80B | INO80 complex subunit B |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KLF15 | Kruppel-like factor 15 |
| LENEP | lens epithelial protein |
| LRRC1 | leucine rich repeat containing 1 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MCM5 | minichromosome maintenance complex component 5 |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MT4 | metallothionein 4 |
| MTMR8 | myotubularin related protein 8 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NCOR2 | nuclear receptor corepressor 2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NIPAL3 | NIPA-like domain containing 3 |
| NMT1 | N-myristoyltransferase 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NXPH4 | neurexophilin 4 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OLFML1 | olfactomedin-like 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRLH | prolactin releasing hormone |
| PROL1 | proline rich, lacrimal 1 |
| PRRC2B | proline-rich coiled-coil 2B |
| PRSS8 | protease, serine, 8 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SHCBP1L | SHC SH2-domain binding protein 1-like |
| SLA | Src-like-adaptor |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SNPH | syntaphilin |
| SPN | sialophorin |
| STAB2 | stabilin 2 |
| TMEM53 | transmembrane protein 53 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TP73-AS1 | TP73 antisense RNA 1 |
| UTRN | utrophin |
| WDR48 | WD repeat domain 48 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| Symbol | Name |
|---|---|
| ADM2 | adrenomedullin 2 |
| AK5 | adenylate kinase 5 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C19ORF57 | chromosome 19 open reading frame 57 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CCDC85C | coiled-coil domain containing 85C |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDC73 | cell division cycle 73 |
| CHN1 | chimerin 1 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLDN11 | claudin 11 |
| CLDN9 | claudin 9 |
| CLK3 | CDC-like kinase 3 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COQ3 | coenzyme Q3 methyltransferase |
| CPOX | coproporphyrinogen oxidase |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DBF4 | DBF4 zinc finger |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DYSF | dysferlin |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| EXOSC9 | exosome component 9 |
| FAM153A | family with sequence similarity 153, member A |
| FGL1 | fibrinogen-like 1 |
| FOXD1 | forkhead box D1 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GSTT1 | glutathione S-transferase theta 1 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRF2 | interferon regulatory factor 2 |
| JAM3 | junctional adhesion molecule 3 |
| KIAA0513 | KIAA0513 |
| KIFAP3 | kinesin-associated protein 3 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| LIN7B | lin-7 homolog B (C. elegans) |
| LUZP4 | leucine zipper protein 4 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORC3 | origin recognition complex, subunit 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLM | polymerase (DNA directed), mu |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB3D | RAB3D, member RAS oncogene family |
| RAD54L | RAD54-like (S. cerevisiae) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RMI1 | RecQ mediated genome instability 1 |
| RNF141 | ring finger protein 141 |
| RNF220 | ring finger protein 220 |
| RNF39 | ring finger protein 39 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SHPK | sedoheptulokinase |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYT2 | synaptotagmin II |
| TBC1D16 | TBC1 domain family, member 16 |
| TBPL1 | TBP-like 1 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| THOC1 | THO complex 1 |
| TJP2 | tight junction protein 2 |
| TMEM184C | transmembrane protein 184C |
| TOM1L1 | target of myb1 (chicken)-like 1 |
| TRIM5 | tripartite motif containing 5 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TTC27 | tetratricopeptide repeat domain 27 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF329 | zinc finger protein 329 |
| ZNF394 | zinc finger protein 394 |
| ZNF408 | zinc finger protein 408 |
