tretinoin-5571 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the tretinoin-5571 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AJAP1 adherens junctions associated protein 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANPEP alanyl (membrane) aminopeptidase
AOX1 aldehyde oxidase 1
AP3B2 adaptor-related protein complex 3, beta 2 subunit
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
ATF6B activating transcription factor 6 beta
BDKRB2 bradykinin receptor B2
BIN1 bridging integrator 1
BTG2 BTG family, member 2
C2ORF54 chromosome 2 open reading frame 54
CDH5 cadherin 5, type 2 (vascular endothelium)
CLEC4E C-type lectin domain family 4, member E
CLMN calmin (calponin-like, transmembrane)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSTA cystatin A (stefin A)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLK2 delta-like 2 homolog (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
DRD1 dopamine receptor D1
DTX2 deltex 2, E3 ubiquitin ligase
DUSP4 dual specificity phosphatase 4
EDN3 endothelin 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPAS1 endothelial PAS domain protein 1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
FAXDC2 fatty acid hydroxylase domain containing 2
FH fumarate hydratase
FMO5 flavin containing monooxygenase 5
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPR35 G protein-coupled receptor 35
HCAR3 hydroxycarboxylic acid receptor 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXA5 homeobox A5
HOXB2 homeobox B2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IQCK IQ motif containing K
IRF1 interferon regulatory factor 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0125 KIAA0125
KLK6 kallikrein-related peptidase 6
LINC00597 long intergenic non-protein coding RNA 597
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAPK11 mitogen-activated protein kinase 11
MARK2 MAP/microtubule affinity-regulating kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
N4BP2L1 NEDD4 binding protein 2-like 1
N4BP3 NEDD4 binding protein 3
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR5A2 nuclear receptor subfamily 5, group A, member 2
NUP188 nucleoporin 188kDa
PADI3 peptidyl arginine deiminase, type III
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G10 phospholipase A2, group X
PRR5 proline rich 5 (renal)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF208 ring finger protein 208
RUNX1 runt-related transcription factor 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELL selectin L
SKAP2 src kinase associated phosphoprotein 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SOX9 SRY (sex determining region Y)-box 9
TAAR5 trace amine associated receptor 5
TBX3 T-box 3
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
TMPRSS2 transmembrane protease, serine 2
TMPRSS4 transmembrane protease, serine 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TOX thymocyte selection-associated high mobility group box
TRIM2 tripartite motif containing 2
TRIM31 tripartite motif containing 31
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSC22D3 TSC22 domain family, member 3
WSCD1 WSC domain containing 1
YY2 YY2 transcription factor
ZFP37 ZFP37 zinc finger protein
ZFPL1 zinc finger protein-like 1
ZNF362 zinc finger protein 362
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACBD4 acyl-CoA binding domain containing 4
AHDC1 AT hook, DNA binding motif, containing 1
ANXA1 annexin A1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAHCC1 BAH domain and coiled-coil containing 1
BAHD1 bromo adjacent homology domain containing 1
BBS7 Bardet-Biedl syndrome 7
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF115 chromosome 1 open reading frame 115
C22ORF29 chromosome 22 open reading frame 29
CA11 carbonic anhydrase XI
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC9 coiled-coil domain containing 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDR2L cerebellar degeneration-related protein 2-like
CIDEC cell death-inducing DFFA-like effector c
CLDN9 claudin 9
CXADR coxsackie virus and adenovirus receptor
DDIT3 DNA-damage-inducible transcript 3
DUSP5 dual specificity phosphatase 5
DUSP8 dual specificity phosphatase 8
EGR3 early growth response 3
EPHB3 EPH receptor B3
ETAA1 Ewing tumor-associated antigen 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GBP2 guanylate binding protein 2, interferon-inducible
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR87 G protein-coupled receptor 87
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRAMD3 GRAM domain containing 3
GSTCD glutathione S-transferase, C-terminal domain containing
HDAC5 histone deacetylase 5
HIST1H2AG histone cluster 1, H2ag
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFI35 interferon-induced protein 35
IGSF3 immunoglobulin superfamily, member 3
INF2 inverted formin, FH2 and WH2 domain containing
IRF6 interferon regulatory factor 6
ITGA10 integrin, alpha 10
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0319L KIAA0319-like
LIN7A lin-7 homolog A (C. elegans)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
LYPD3 LY6/PLAUR domain containing 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MATK megakaryocyte-associated tyrosine kinase
MCOLN1 mucolipin 1
NDE1 nudE neurodevelopment protein 1
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
OGFRL1 opioid growth factor receptor-like 1
PER3 period circadian clock 3
PEX26 peroxisomal biogenesis factor 26
PGBD5 piggyBac transposable element derived 5
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLAUR plasminogen activator, urokinase receptor
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRR15L proline rich 15-like
PRSS16 protease, serine, 16 (thymus)
RHOB ras homolog family member B
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SFXN3 sideroflexin 3
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35E3 solute carrier family 35, member E3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLMO1 slowmo homolog 1 (Drosophila)
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SRD5A3 steroid 5 alpha-reductase 3
SSBP2 single-stranded DNA binding protein 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STARD5 StAR-related lipid transfer (START) domain containing 5
TEAD3 TEA domain family member 3
THRAP3 thyroid hormone receptor associated protein 3
TMPRSS3 transmembrane protease, serine 3
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRAIP TRAF interacting protein
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBTD1 ubiquitin domain containing 1
ZBTB44 zinc finger and BTB domain containing 44
ZMYM3 zinc finger, MYM-type 3
ZNF329 zinc finger protein 329
ZNF747 zinc finger protein 747