tretinoin-5767 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the tretinoin-5767 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY2 adenylate cyclase 2 (brain)
ADORA1 adenosine A1 receptor
ADORA3 adenosine A3 receptor
AFF2 AF4/FMR2 family, member 2
ALDOB aldolase B, fructose-bisphosphate
ANGPTL4 angiopoietin-like 4
ANXA10 annexin A10
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARG1 arginase 1
ARMCX2 armadillo repeat containing, X-linked 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP9A ATPase, class II, type 9A
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCAS1 breast carcinoma amplified sequence 1
BCL2 B-cell CLL/lymphoma 2
BEGAIN brain-enriched guanylate kinase-associated
CADM3 cell adhesion molecule 3
CARTPT CART prepropeptide
CCDC132 coiled-coil domain containing 132
CD200 CD200 molecule
CD58 CD58 molecule
CDRT1 CMT1A duplicated region transcript 1
CELF2 CUGBP, Elav-like family member 2
CHODL chondrolectin
CNGA1 cyclic nucleotide gated channel alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPZ carboxypeptidase Z
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
ELSPBP1 epididymal sperm binding protein 1
EPAS1 endothelial PAS domain protein 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPM6A glycoprotein M6A
GRIK5 glutamate receptor, ionotropic, kainate 5
HABP2 hyaluronan binding protein 2
HAL histidine ammonia-lyase
HFE hemochromatosis
HIST1H4H histone cluster 1, H4h
HMOX1 heme oxygenase 1
HRG histidine-rich glycoprotein
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ICOS inducible T-cell co-stimulator
IL12A interleukin 12A
IL36A interleukin 36, alpha
IRX5 iroquois homeobox 5
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
KANK3 KN motif and ankyrin repeat domains 3
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LINC00216 long intergenic non-protein coding RNA 216
LINC00312 long intergenic non-protein coding RNA 312
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MCF2L MCF.2 cell line derived transforming sequence-like
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MYH14 myosin, heavy chain 14, non-muscle
MYO9B myosin IXB
MYRF myelin regulatory factor
NEB nebulin
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NPTXR neuronal pentraxin receptor
NPY2R neuropeptide Y receptor Y2
NSUN6 NOP2/Sun domain family, member 6
OGFR opioid growth factor receptor
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX7 paired box 7
PLCH1 phospholipase C, eta 1
POSTN periostin, osteoblast specific factor
PRICKLE3 prickle homolog 3 (Drosophila)
PRND prion protein 2 (dublet)
PRSS22 protease, serine, 22
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RBBP9 retinoblastoma binding protein 9
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RHEB Ras homolog enriched in brain
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLMO1 slowmo homolog 1 (Drosophila)
SMO smoothened, frizzled class receptor
SPEF1 sperm flagellar 1
STAT2 signal transducer and activator of transcription 2, 113kDa
SV2B synaptic vesicle glycoprotein 2B
TBL2 transducin (beta)-like 2
TBX1 T-box 1
TCP10 t-complex 10
TET3 tet methylcytosine dioxygenase 3
TP53TG5 TP53 target 5
TRO trophinin
WT1 Wilms tumor 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB7A zinc finger and BTB domain containing 7A
ZC2HC1C zinc finger, C2HC-type containing 1C

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ALS2CL ALS2 C-terminal like
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
AXIN1 axin 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCORL1 BCL6 corepressor-like 1
BOLA1 bolA family member 1
BTBD2 BTB (POZ) domain containing 2
C11ORF80 chromosome 11 open reading frame 80
C1RL complement component 1, r subcomponent-like
CDK3 cyclin-dependent kinase 3
CEP70 centrosomal protein 70kDa
CLEC2B C-type lectin domain family 2, member B
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COQ4 coenzyme Q4
CORO2A coronin, actin binding protein, 2A
CSF1R colony stimulating factor 1 receptor
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTNNBIP1 catenin, beta interacting protein 1
CUL9 cullin 9
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL3 chemokine (C-X-C motif) ligand 3
DBF4B DBF4 zinc finger B
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EXOC6B exocyst complex component 6B
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM127B family with sequence similarity 127, member B
FAM184A family with sequence similarity 184, member A
FBXL7 F-box and leucine-rich repeat protein 7
FKBP10 FK506 binding protein 10, 65 kDa
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXC1 forkhead box C1
FURIN furin (paired basic amino acid cleaving enzyme)
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALK1 galactokinase 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNL1 guanine nucleotide binding protein-like 1
GRTP1 growth hormone regulated TBC protein 1
HDAC5 histone deacetylase 5
HIST1H4C histone cluster 1, H4c
HIST1H4E histone cluster 1, H4e
HMHA1 histocompatibility (minor) HA-1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT81 intraflagellar transport 81
IL7R interleukin 7 receptor
KIAA0754 KIAA0754
KIFC1 kinesin family member C1
KRT86 keratin 86, type II
LMNB1 lamin B1
LRRK1 leucine-rich repeat kinase 1
MDFI MyoD family inhibitor
MED15 mediator complex subunit 15
MST1R macrophage stimulating 1 receptor
MXD3 MAX dimerization protein 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NECAP2 NECAP endocytosis associated 2
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PCDH17 protocadherin 17
PCDHGB5 protocadherin gamma subfamily B, 5
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCD1 phospholipase C, delta 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLK2 polo-like kinase 2
POMT2 protein-O-mannosyltransferase 2
PRPH peripherin
RAB4B RAB4B, member RAS oncogene family
RHOBTB2 Rho-related BTB domain containing 2
ROGDI rogdi homolog (Drosophila)
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCARA3 scavenger receptor class A, member 3
SCML2 sex comb on midleg-like 2 (Drosophila)
SDC3 syndecan 3
SECISBP2 SECIS binding protein 2
SETBP1 SET binding protein 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SMAD7 SMAD family member 7
SNPH syntaphilin
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
ST5 suppression of tumorigenicity 5
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TMEM159 transmembrane protein 159
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAF2 TNF receptor-associated factor 2
TRIM66 tripartite motif containing 66
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
VEZT vezatin, adherens junctions transmembrane protein
VWA1 von Willebrand factor A domain containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZFP30 ZFP30 zinc finger protein