tretinoin-6170 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the tretinoin-6170 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AIM2 absent in melanoma 2
ANGPTL4 angiopoietin-like 4
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATP13A2 ATPase type 13A2
BCL2A1 BCL2-related protein A1
BCL6 B-cell CLL/lymphoma 6
C1ORF106 chromosome 1 open reading frame 106
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CCR1 chemokine (C-C motif) receptor 1
CD1D CD1d molecule
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CFP complement factor properdin
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL4A2 collagen, type IV, alpha 2
COLEC12 collectin sub-family member 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DAPK1 death-associated protein kinase 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EFNB2 ephrin-B2
EMP2 epithelial membrane protein 2
ENDOD1 endonuclease domain containing 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EXPH5 exophilin 5
FAM134B family with sequence similarity 134, member B
FAM13A family with sequence similarity 13, member A
FBP1 fructose-1,6-bisphosphatase 1
FGF9 fibroblast growth factor 9
FGR FGR proto-oncogene, Src family tyrosine kinase
FLNB filamin B, beta
FLOT1 flotillin 1
FMO5 flavin containing monooxygenase 5
G0S2 G0/G1 switch 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
HAB1 B1 for mucin
HBEGF heparin-binding EGF-like growth factor
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXA5 homeobox A5
HPD 4-hydroxyphenylpyruvate dioxygenase
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFI30 interferon, gamma-inducible protein 30
ITGA6 integrin, alpha 6
KIAA0513 KIAA0513
LAMB3 laminin, beta 3
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
MERTK MER proto-oncogene, tyrosine kinase
MLXIPL MLX interacting protein-like
MUC1 mucin 1, cell surface associated
MYBPH myosin binding protein H
NCF1C neutrophil cytosolic factor 1C pseudogene
NFE2 nuclear factor, erythroid 2
NINJ1 ninjurin 1
NRIP1 nuclear receptor interacting protein 1
NTSR1 neurotensin receptor 1 (high affinity)
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PALLD palladin, cytoskeletal associated protein
PDLIM5 PDZ and LIM domain 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POR P450 (cytochrome) oxidoreductase
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRKCH protein kinase C, eta
PTGES prostaglandin E synthase
RAB20 RAB20, member RAS oncogene family
RHOBTB3 Rho-related BTB domain containing 3
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLA Src-like-adaptor
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMAD3 SMAD family member 3
SMOX spermine oxidase
SOAT1 sterol O-acyltransferase 1
STX11 syntaxin 11
TBC1D2 TBC1 domain family, member 2
TBL2 transducin (beta)-like 2
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TNNI2 troponin I type 2 (skeletal, fast)
TREM1 triggering receptor expressed on myeloid cells 1
UPB1 ureidopropionase, beta
UPP1 uridine phosphorylase 1

decreased expression

Symbol Name
AEN apoptosis enhancing nuclease
ANKRD28 ankyrin repeat domain 28
ANKRD55 ankyrin repeat domain 55
ATAT1 alpha tubulin acetyltransferase 1
ATXN2L ataxin 2-like
BAHCC1 BAH domain and coiled-coil containing 1
BAMBI BMP and activin membrane-bound inhibitor
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCAS3 breast carcinoma amplified sequence 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C2CD2 C2 calcium-dependent domain containing 2
C2ORF54 chromosome 2 open reading frame 54
CD1C CD1c molecule
CD69 CD69 molecule
CDK20 cyclin-dependent kinase 20
CES3 carboxylesterase 3
CGREF1 cell growth regulator with EF-hand domain 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIC capicua transcriptional repressor
CLEC4E C-type lectin domain family 4, member E
CLEC5A C-type lectin domain family 5, member A
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPA4 carboxypeptidase A4
CPNE7 copine VII
CTSG cathepsin G
DDN dendrin
DEPTOR DEP domain containing MTOR-interacting protein
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
FAM131A family with sequence similarity 131, member A
FAM86B1 family with sequence similarity 86, member B1
FKBP5 FK506 binding protein 5
GAA glucosidase, alpha; acid
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GALK1 galactokinase 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HMGA2 high mobility group AT-hook 2
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HTRA1 HtrA serine peptidase 1
HYAL3 hyaluronoglucosaminidase 3
IDI2-AS1 IDI2 antisense RNA 1
IGFBP4 insulin-like growth factor binding protein 4
IL1R2 interleukin 1 receptor, type II
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
IRX5 iroquois homeobox 5
ISG15 ISG15 ubiquitin-like modifier
KLF1 Kruppel-like factor 1 (erythroid)
LOC157562 uncharacterized LOC157562
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP5 low density lipoprotein receptor-related protein 5
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP6D1 MAP6 domain containing 1
MEFV Mediterranean fever
METTL8 methyltransferase like 8
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MKL2 MKL/myocardin-like 2
MTA2 metastasis associated 1 family, member 2
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO15A myosin XVA
NAT6 N-acetyltransferase 6 (GCN5-related)
NCS1 neuronal calcium sensor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NR1D2 nuclear receptor subfamily 1, group D, member 2
NTHL1 nth endonuclease III-like 1 (E. coli)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OMG oligodendrocyte myelin glycoprotein
PFN2 profilin 2
PID1 phosphotyrosine interaction domain containing 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLP1 proteolipid protein 1
POLH polymerase (DNA directed), eta
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PRKCE protein kinase C, epsilon
PRY PTPN13-like, Y-linked
PTX3 pentraxin 3, long
QTRT1 queuine tRNA-ribosyltransferase 1
RGS19 regulator of G-protein signaling 19
RNF126P1 ring finger protein 126 pseudogene 1
SCAMP5 secretory carrier membrane protein 5
SETD1A SET domain containing 1A
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNHG3 small nucleolar RNA host gene 3
TM6SF1 transmembrane 6 superfamily member 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNNT1 troponin T type 1 (skeletal, slow)
TRAC T cell receptor alpha constant
TTC4 tetratricopeptide repeat domain 4
TUBA3D tubulin, alpha 3d
TUBB2A tubulin, beta 2A class IIa
VNN1 vanin 1
WT1-AS WT1 antisense RNA
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF219 zinc finger protein 219
ZNF528 zinc finger protein 528