| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the tretinoin-849 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALS2CL | ALS2 C-terminal like |
| ARTN | artemin |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BCL3 | B-cell CLL/lymphoma 3 |
| BDKRB2 | bradykinin receptor B2 |
| BTG2 | BTG family, member 2 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNO | cyclin O |
| CDH5 | cadherin 5, type 2 (vascular endothelium) |
| CLMN | calmin (calponin-like, transmembrane) |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CRY2 | cryptochrome circadian clock 2 |
| CSTA | cystatin A (stefin A) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DLX2 | distal-less homeobox 2 |
| DOPEY2 | dopey family member 2 |
| DUSP4 | dual specificity phosphatase 4 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EPAS1 | endothelial PAS domain protein 1 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| FAM174B | family with sequence similarity 174, member B |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| FZD5 | frizzled class receptor 5 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| HHEX | hematopoietically expressed homeobox |
| HLA-G | major histocompatibility complex, class I, G |
| HOXA1 | homeobox A1 |
| HOXA4 | homeobox A4 |
| HOXA5 | homeobox A5 |
| HOXB2 | homeobox B2 |
| HOXC13 | homeobox C13 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IRF1 | interferon regulatory factor 1 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KAZN | kazrin, periplakin interacting protein |
| KRT13 | keratin 13, type I |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIMCH1 | LIM and calponin homology domains 1 |
| LOXL1 | lysyl oxidase-like 1 |
| METTL7A | methyltransferase like 7A |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MID1IP1 | MID1 interacting protein 1 |
| NAV2 | neuron navigator 2 |
| OPN3 | opsin 3 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PADI3 | peptidyl arginine deiminase, type III |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLA2G10 | phospholipase A2, group X |
| PRMT2IP | PRMT2 interacting protein |
| PRR5 | proline rich 5 (renal) |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 |
| PTGES | prostaglandin E synthase |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RAP1GAP | RAP1 GTPase activating protein |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SIK1 | salt-inducible kinase 1 |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMAD3 | SMAD family member 3 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SSPN | sarcospan |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMPRSS2 | transmembrane protease, serine 2 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TRIM31 | tripartite motif containing 31 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BMP4 | bone morphogenetic protein 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CALHM2 | calcium homeostasis modulator 2 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDC42SE1 | CDC42 small effector 1 |
| CLSPN | claspin |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CUEDC1 | CUE domain containing 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAL4 | dynein, axonemal, light chain 4 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EGR3 | early growth response 3 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| EXOC5 | exocyst complex component 5 |
| FA2H | fatty acid 2-hydroxylase |
| FANCC | Fanconi anemia, complementation group C |
| FGF23 | fibroblast growth factor 23 |
| FOSL1 | FOS-like antigen 1 |
| FZD4 | frizzled class receptor 4 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPATCH2L | G patch domain containing 2-like |
| GPR27 | G protein-coupled receptor 27 |
| GTPBP2 | GTP binding protein 2 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3G | histone cluster 1, H3g |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MANSC1 | MANSC domain containing 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED15 | mediator complex subunit 15 |
| MISP | mitotic spindle positioning |
| MTA2 | metastasis associated 1 family, member 2 |
| MTSS1L | metastasis suppressor 1-like |
| MXD3 | MAX dimerization protein 3 |
| MYLIP | myosin regulatory light chain interacting protein |
| NMU | neuromedin U |
| NPY1R | neuropeptide Y receptor Y1 |
| NPY5R | neuropeptide Y receptor Y5 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PMP22 | peripheral myelin protein 22 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RNF170 | ring finger protein 170 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF2 | ring finger protein 2 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA1 | spermatogenesis associated 1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SREK1IP1 | SREK1-interacting protein 1 |
| TCTN2 | tectonic family member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIGD6 | tigger transposable element derived 6 |
| TMEM212 | transmembrane protein 212 |
| TNS2 | tensin 2 |
| TRAF5 | TNF receptor-associated factor 5 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| VASH1 | vasohibin 1 |
| VGF | VGF nerve growth factor inducible |
| WWC2 | WW and C2 domain containing 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF268 | zinc finger protein 268 |
| ZNF532 | zinc finger protein 532 |
| ZNF571 | zinc finger protein 571 |
| ZNF675 | zinc finger protein 675 |