triamterene-1697 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the triamterene-1697 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADRBK1 adrenergic, beta, receptor kinase 1
ANGPT1 angiopoietin 1
ANGPTL2 angiopoietin-like 2
AOX1 aldehyde oxidase 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASB1 ankyrin repeat and SOCS box containing 1
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
B9D1 B9 protein domain 1
BMP1 bone morphogenetic protein 1
BMP4 bone morphogenetic protein 4
C22ORF29 chromosome 22 open reading frame 29
C7ORF69 chromosome 7 open reading frame 69
CD6 CD6 molecule
CD83 CD83 molecule
CDK3 cyclin-dependent kinase 3
CTNS cystinosin, lysosomal cystine transporter
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
FAM182B family with sequence similarity 182, member B
FKBP10 FK506 binding protein 10, 65 kDa
FLOT1 flotillin 1
FSCN1 fascin actin-bundling protein 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GJA8 gap junction protein, alpha 8, 50kDa
GK glycerol kinase
GPR153 G protein-coupled receptor 153
GUCA1A guanylate cyclase activator 1A (retina)
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
ICOSLG inducible T-cell co-stimulator ligand
INO80D INO80 complex subunit D
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KREMEN2 kringle containing transmembrane protein 2
KRIT1 KRIT1, ankyrin repeat containing
KRT75 keratin 75, type II
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
METTL5 methyltransferase like 5
MINK1 misshapen-like kinase 1
MST1 macrophage stimulating 1
MTA1 metastasis associated 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCAPH2 non-SMC condensin II complex, subunit H2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPM3 nucleophosmin/nucleoplasmin 3
NR2F1 nuclear receptor subfamily 2, group F, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PARD6B par-6 family cell polarity regulator beta
PCDH9 protocadherin 9
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTGES prostaglandin E synthase
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB27B RAB27B, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RAD52 RAD52 homolog (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP3 RAN binding protein 3
REEP1 receptor accessory protein 1
REST RE1-silencing transcription factor
RIN2 Ras and Rab interactor 2
RNF126P1 ring finger protein 126 pseudogene 1
RPL7 ribosomal protein L7
RYR2 ryanodine receptor 2 (cardiac)
SIRT5 sirtuin 5
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG7 SMG7 nonsense mediated mRNA decay factor
SMR3A submaxillary gland androgen regulated protein 3A
SOX10 SRY (sex determining region Y)-box 10
SOX9 SRY (sex determining region Y)-box 9
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SRD5A3 steroid 5 alpha-reductase 3
STX7 syntaxin 7
TADA2A transcriptional adaptor 2A
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TECPR2 tectonin beta-propeller repeat containing 2
TJAP1 tight junction associated protein 1 (peripheral)
TM2D1 TM2 domain containing 1
TMEM209 transmembrane protein 209
TPMT thiopurine S-methyltransferase
TPR translocated promoter region, nuclear basket protein
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VIPR2 vasoactive intestinal peptide receptor 2
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPL1 zinc finger protein-like 1
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACTN4 actinin, alpha 4
ADCY6 adenylate cyclase 6
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANXA2P3 annexin A2 pseudogene 3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMC6 armadillo repeat containing 6
ARRB1 arrestin, beta 1
ATXN2 ataxin 2
AXIN1 axin 1
BACE1 beta-site APP-cleaving enzyme 1
BAHD1 bromo adjacent homology domain containing 1
BATF basic leucine zipper transcription factor, ATF-like
BCL9 B-cell CLL/lymphoma 9
BRPF1 bromodomain and PHD finger containing, 1
C2ORF44 chromosome 2 open reading frame 44
CAPG capping protein (actin filament), gelsolin-like
CAPN15 calpain 15
CAPRIN2 caprin family member 2
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CBX4 chromobox homolog 4
CIC capicua transcriptional repressor
CLEC16A C-type lectin domain family 16, member A
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORO1A coronin, actin binding protein, 1A
CTC1 CTS telomere maintenance complex component 1
CTNNBL1 catenin, beta like 1
CUL9 cullin 9
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DAP death-associated protein
DENND1B DENN/MADD domain containing 1B
EIF5A2 eukaryotic translation initiation factor 5A2
EPHA2 EPH receptor A2
ERO1L ERO1-like (S. cerevisiae)
FAM127B family with sequence similarity 127, member B
FAM188A family with sequence similarity 188, member A
FBXL6 F-box and leucine-rich repeat protein 6
FBXO22 F-box protein 22
FEM1C fem-1 homolog c (C. elegans)
FLT4 fms-related tyrosine kinase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAA glucosidase, alpha; acid
GLTSCR1 glioma tumor suppressor candidate region gene 1
HOXC11 homeobox C11
IGSF1 immunoglobulin superfamily, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LIN7A lin-7 homolog A (C. elegans)
LOC642236 FSHD region gene 1 pseudogene
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP7D1 MAP7 domain containing 1
MED15 mediator complex subunit 15
MTERF1 mitochondrial transcription termination factor 1
MVD mevalonate (diphospho) decarboxylase
MYO1D myosin ID
NABP2 nucleic acid binding protein 2
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
NEK11 NIMA-related kinase 11
NES nestin
NPY1R neuropeptide Y receptor Y1
OCLN occludin
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRKCD protein kinase C, delta
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM42 RNA binding motif protein 42
RIC8B RIC8 guanine nucleotide exchange factor B
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCPEP1 serine carboxypeptidase 1
SHARPIN SHANK-associated RH domain interactor
SNIP1 Smad nuclear interacting protein 1
SOX12 SRY (sex determining region Y)-box 12
STAG3 stromal antigen 3
TLN1 talin 1
TMC7 transmembrane channel-like 7
TMEM120B transmembrane protein 120B
TMEM62 transmembrane protein 62
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC30A tetratricopeptide repeat domain 30A
UFSP2 UFM1-specific peptidase 2
VASH1 vasohibin 1
VWA1 von Willebrand factor A domain containing 1
WDR4 WD repeat domain 4
WDR46 WD repeat domain 46
XKR8 XK, Kell blood group complex subunit-related family, member 8
XYLT2 xylosyltransferase II
YIPF1 Yip1 domain family, member 1
ZC3H3 zinc finger CCCH-type containing 3
ZMAT5 zinc finger, matrin-type 5
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF32 zinc finger protein 32
ZNF586 zinc finger protein 586
ZSCAN31 zinc finger and SCAN domain containing 31
ZW10 zw10 kinetochore protein
ZYX zyxin