| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the triamterene-1819 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ANGPTL4 | angiopoietin-like 4 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BCL2A1 | BCL2-related protein A1 |
| BMP2 | bone morphogenetic protein 2 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CA12 | carbonic anhydrase XII |
| CAPN2 | calpain 2, (m/II) large subunit |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD58 | CD58 molecule |
| CDC73 | cell division cycle 73 |
| CHD1L | chromodomain helicase DNA binding protein 1-like |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CREM | cAMP responsive element modulator |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTH | cystathionine gamma-lyase |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUSP1 | dual specificity phosphatase 1 |
| ECE1 | endothelin converting enzyme 1 |
| FAM129A | family with sequence similarity 129, member A |
| FBN1 | fibrillin 1 |
| FLOT1 | flotillin 1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GK | glycerol kinase |
| GLRX | glutaredoxin (thioltransferase) |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITM2B | integral membrane protein 2B |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KIRREL | kin of IRRE like (Drosophila) |
| KLF6 | Kruppel-like factor 6 |
| KLK10 | kallikrein-related peptidase 10 |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC644450 | uncharacterized LOC644450 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MED28 | mediator complex subunit 28 |
| MED6 | mediator complex subunit 6 |
| MRPS11 | mitochondrial ribosomal protein S11 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NF1 | neurofibromin 1 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PTAFR | platelet-activating factor receptor |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCEL | sciellin |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM50B | transmembrane protein 50B |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM2 | tripartite motif containing 2 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| UBOX5 | U-box domain containing 5 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF33B | zinc finger protein 33B |
| ZNF473 | zinc finger protein 473 |
| ZNF609 | zinc finger protein 609 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAPN5 | calpain 5 |
| CCNT1 | cyclin T1 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CROT | carnitine O-octanoyltransferase |
| DENND4B | DENN/MADD domain containing 4B |
| DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| EDN1 | endothelin 1 |
| EPPK1 | epiplakin 1 |
| FBRS | fibrosin |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLJ22184 | |
| FPGS | folylpolyglutamate synthase |
| GALK1 | galactokinase 1 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPATCH2 | G patch domain containing 2 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KIFC1 | kinesin family member C1 |
| KPTN | kaptin (actin binding protein) |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LMNB1 | lamin B1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC61 | leucine rich repeat containing 61 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MXRA8 | matrix-remodelling associated 8 |
| MYLK | myosin light chain kinase |
| NPR3 | natriuretic peptide receptor 3 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCBP4 | poly(rC) binding protein 4 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDZK1 | PDZ domain containing 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POLH | polymerase (DNA directed), eta |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RIN1 | Ras and Rab interactor 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SESN1 | sestrin 1 |
| SIX1 | SIX homeobox 1 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SMAD7 | SMAD family member 7 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| ST5 | suppression of tumorigenicity 5 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TAGLN3 | transgelin 3 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D2 | TBC1 domain family, member 2 |
| TGFB3 | transforming growth factor, beta 3 |
| TKFC | triokinase/FMN cyclase |
| TMEM132A | transmembrane protein 132A |
| TSC22D4 | TSC22 domain family, member 4 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF276 | zinc finger protein 276 |
| ZNF32 | zinc finger protein 32 |
| ZNF324 | zinc finger protein 324 |
| ZNF668 | zinc finger protein 668 |
| ZNF8 | zinc finger protein 8 |
| ZNF816 | zinc finger protein 816 |
| ZXDC | ZXD family zinc finger C |
