triamterene-1861 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the triamterene-1861 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
AEN apoptosis enhancing nuclease
AIM1L absent in melanoma 1-like
ANKH ANKH inorganic pyrophosphate transport regulator
ARMC7 armadillo repeat containing 7
ARNTL aryl hydrocarbon receptor nuclear translocator-like
BBC3 BCL2 binding component 3
BCAP29 B-cell receptor-associated protein 29
BMP15 bone morphogenetic protein 15
C9ORF3 chromosome 9 open reading frame 3
CACYBP calcyclin binding protein
CD6 CD6 molecule
CDH8 cadherin 8, type 2
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CRABP2 cellular retinoic acid binding protein 2
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSNK1E casein kinase 1, epsilon
CUX2 cut-like homeobox 2
CXCL10 chemokine (C-X-C motif) ligand 10
CYB561 cytochrome b561
DEAF1 DEAF1 transcription factor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC1 exosome component 1
FAM131A family with sequence similarity 131, member A
FOXP3 forkhead box P3
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GK glycerol kinase
GOSR2 golgi SNAP receptor complex member 2
GRPR gastrin-releasing peptide receptor
HIPK2 homeodomain interacting protein kinase 2
IGFBP5 insulin-like growth factor binding protein 5
ITGA10 integrin, alpha 10
JMJD4 jumonji domain containing 4
KAT6B K(lysine) acetyltransferase 6B
KIF1A kinesin family member 1A
KLF3 Kruppel-like factor 3 (basic)
KMT2A lysine (K)-specific methyltransferase 2A
LAT2 linker for activation of T cells family, member 2
LOC390998 ribosomal protein L10 pseudogene
LOC399491
MAP2K3 mitogen-activated protein kinase kinase 3
MAP7 microtubule-associated protein 7
MED16 mediator complex subunit 16
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTAP methylthioadenosine phosphorylase
MYO19 myosin XIX
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR4A1 nuclear receptor subfamily 4, group A, member 1
NXF2 nuclear RNA export factor 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAQR6 progestin and adipoQ receptor family member VI
PARD3 par-3 family cell polarity regulator
PCGF2 polycomb group ring finger 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLXNA1 plexin A1
PRDX2 peroxiredoxin 2
PROS1 protein S (alpha)
PRR5 proline rich 5 (renal)
PTN pleiotrophin
PVR poliovirus receptor
R3HCC1L R3H domain and coiled-coil containing 1-like
RAD52 RAD52 homolog (S. cerevisiae)
RAP1GAP RAP1 GTPase activating protein
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RET ret proto-oncogene
RIN3 Ras and Rab interactor 3
RPL18 ribosomal protein L18
RPL35A ribosomal protein L35a
RSU1 Ras suppressor protein 1
RTEL1 regulator of telomere elongation helicase 1
SFTPB surfactant protein B
SH2D2A SH2 domain containing 2A
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRT5 sirtuin 5
SMAD3 SMAD family member 3
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SSTR5 somatostatin receptor 5
SUGP1 SURP and G patch domain containing 1
SYNJ1 synaptojanin 1
TAS2R10 taste receptor, type 2, member 10
TCP10 t-complex 10
THBS1 thrombospondin 1
TM4SF5 transmembrane 4 L six family member 5
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRDMT1 tRNA aspartic acid methyltransferase 1
TSPYL2 TSPY-like 2
TTC38 tetratricopeptide repeat domain 38
TXNL4A thioredoxin-like 4A
XDH xanthine dehydrogenase
ZNF174 zinc finger protein 174
ZNF667 zinc finger protein 667
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AZI2 5-azacytidine induced 2
C11ORF95 chromosome 11 open reading frame 95
C3 complement component 3
CCNB1 cyclin B1
CD52 CD52 molecule
CD82 CD82 molecule
CDC20 cell division cycle 20
CDCA3 cell division cycle associated 3
CENPC centromere protein C
CENPE centromere protein E, 312kDa
CGREF1 cell growth regulator with EF-hand domain 1
CORO7 coronin 7
CREB3 cAMP responsive element binding protein 3
CYBA cytochrome b-245, alpha polypeptide
DEPDC1 DEP domain containing 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNASE1L1 deoxyribonuclease I-like 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
ECT2 epithelial cell transforming 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FBXO3 F-box protein 3
FN3KRP fructosamine 3 kinase related protein
GPR63 G protein-coupled receptor 63
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
HDAC4 histone deacetylase 4
HIST3H2A histone cluster 3, H2a
HMMR hyaluronan-mediated motility receptor (RHAMM)
IPO8 importin 8
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0753 KIAA0753
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIMD2 LIM domain containing 2
LZTR1 leucine-zipper-like transcription regulator 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MMP2 matrix metallopeptidase 2
MON1B MON1 secretory trafficking family member B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF1 mitochondrial transcription termination factor 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCAPH non-SMC condensin I complex, subunit H
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NHEJ1 nonhomologous end-joining factor 1
NISCH nischarin
ODF2 outer dense fiber of sperm tails 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARPBP PARP1 binding protein
PDLIM2 PDZ and LIM domain 2 (mystique)
PFAS phosphoribosylformylglycinamidine synthase
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLK1 polo-like kinase 1
POR P450 (cytochrome) oxidoreductase
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSRC1 proline/serine-rich coiled-coil 1
RABL6 RAB, member RAS oncogene family-like 6
RARS arginyl-tRNA synthetase
RETN resistin
RPUSD2 RNA pseudouridylate synthase domain containing 2
SCML1 sex comb on midleg-like 1 (Drosophila)
SHARPIN SHANK-associated RH domain interactor
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SND1-IT1 SND1 intronic transcript 1
SNHG20 small nucleolar RNA host gene 20
SNX15 sorting nexin 15
SPDL1 spindle apparatus coiled-coil protein 1
SPON2 spondin 2, extracellular matrix protein
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TEC tec protein tyrosine kinase
TMEM14A transmembrane protein 14A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM25 tripartite motif containing 25
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
UBE2S ubiquitin-conjugating enzyme E2S
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZNF232 zinc finger protein 232
ZNF248 zinc finger protein 248
ZNF280D zinc finger protein 280D
ZNF552 zinc finger protein 552
ZNF576 zinc finger protein 576
ZNF587 zinc finger protein 587
ZNF606 zinc finger protein 606
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZW10 zw10 kinetochore protein