triamterene-6010 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the triamterene-6010 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACTC1 actin, alpha, cardiac muscle 1
AK1 adenylate kinase 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
APAF1 apoptotic peptidase activating factor 1
ASIC4 acid sensing (proton gated) ion channel family member 4
ATN1 atrophin 1
BAIAP3 BAI1-associated protein 3
BCL2 B-cell CLL/lymphoma 2
BMP10 bone morphogenetic protein 10
C8A complement component 8, alpha polypeptide
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CADM3 cell adhesion molecule 3
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
COL5A1 collagen, type V, alpha 1
CSHL1 chorionic somatomammotropin hormone-like 1
CYHR1 cysteine/histidine-rich 1
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DGCR8 DGCR8 microprocessor complex subunit
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOCK9 dedicator of cytokinesis 9
DOK4 docking protein 4
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ESR1 estrogen receptor 1
FADS3 fatty acid desaturase 3
FAM212B family with sequence similarity 212, member B
FCGBP Fc fragment of IgG binding protein
FN1 fibronectin 1
FSHB follicle stimulating hormone, beta polypeptide
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRK4 G protein-coupled receptor kinase 4
GUSBP3 glucuronidase, beta pseudogene 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL4R interleukin 4 receptor
ING4 inhibitor of growth family, member 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
JAG1 jagged 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDM4C lysine (K)-specific demethylase 4C
KRIT1 KRIT1, ankyrin repeat containing
LAMC2 laminin, gamma 2
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMK1 LIM domain kinase 1
LINC00597 long intergenic non-protein coding RNA 597
LOC390998 ribosomal protein L10 pseudogene
LOXL3 lysyl oxidase-like 3
LZTR1 leucine-zipper-like transcription regulator 1
METTL7A methyltransferase like 7A
MOCS1 molybdenum cofactor synthesis 1
MYH14 myosin, heavy chain 14, non-muscle
NCKIPSD NCK interacting protein with SH3 domain
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NPIPB3 nuclear pore complex interacting protein family, member B3
NR4A2 nuclear receptor subfamily 4, group A, member 2
PBX2 pre-B-cell leukemia homeobox 2
PCDH17 protocadherin 17
PGAP1 post-GPI attachment to proteins 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCD1 phospholipase C, delta 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLM polymerase (DNA directed), mu
POU6F1 POU class 6 homeobox 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRR16 proline rich 16
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB14 RAB14, member RAS oncogene family
RBM19 RNA binding motif protein 19
REEP2 receptor accessory protein 2
RETN resistin
RPL23AP32 ribosomal protein L23a pseudogene 32
RSU1 Ras suppressor protein 1
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SCAMP1 secretory carrier membrane protein 1
SH3BP2 SH3-domain binding protein 2
SIM2 single-minded family bHLH transcription factor 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG6 SMG6 nonsense mediated mRNA decay factor
SMTN smoothelin
SRCAP Snf2-related CREBBP activator protein
SRSF7 serine/arginine-rich splicing factor 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STATH statherin
SYNGR1 synaptogyrin 1
TNPO2 transportin 2
TP63 tumor protein p63
TRIM21 tripartite motif containing 21
TUBA4B tubulin, alpha 4b
VGF VGF nerve growth factor inducible
WLS wntless Wnt ligand secretion mediator
XAF1 XIAP associated factor 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF37BP zinc finger protein 37B, pseudogene
ZNF391 zinc finger protein 391
ZNF821 zinc finger protein 821
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABI3BP ABI family, member 3 (NESH) binding protein
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AMT aminomethyltransferase
ARC activity-regulated cytoskeleton-associated protein
ARMC6 armadillo repeat containing 6
B9D2 B9 protein domain 2
C11ORF63 chromosome 11 open reading frame 63
C22ORF46 chromosome 22 open reading frame 46
CARTPT CART prepropeptide
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK20 cyclin-dependent kinase 20
CENPO centromere protein O
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CIC capicua transcriptional repressor
CIDEB cell death-inducing DFFA-like effector b
CSF1R colony stimulating factor 1 receptor
CXXC4 CXXC finger protein 4
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELSPBP1 epididymal sperm binding protein 1
FAM120C family with sequence similarity 120C
FAM169A family with sequence similarity 169, member A
FBXO46 F-box protein 46
FGF23 fibroblast growth factor 23
FGGY FGGY carbohydrate kinase domain containing
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR19 G protein-coupled receptor 19
HYI hydroxypyruvate isomerase (putative)
IDI2-AS1 IDI2 antisense RNA 1
IFT81 intraflagellar transport 81
IRF9 interferon regulatory factor 9
KLHL26 kelch-like family member 26
LINS lines homolog (Drosophila)
LTC4S leukotriene C4 synthase
LYRM9 LYR motif containing 9
MBNL3 muscleblind-like splicing regulator 3
MED9 mediator complex subunit 9
MFAP2 microfibrillar-associated protein 2
MRAS muscle RAS oncogene homolog
MTG1 mitochondrial ribosome-associated GTPase 1
MYO1E myosin IE
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEUROD4 neuronal differentiation 4
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVOL1 ovo-like zinc finger 1
PCBP4 poly(rC) binding protein 4
PDE12 phosphodiesterase 12
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PITX2 paired-like homeodomain 2
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPT2 palmitoyl-protein thioesterase 2
PRF1 perforin 1 (pore forming protein)
PROL1 proline rich, lacrimal 1
PRPH peripherin
RIBC2 RIB43A domain with coiled-coils 2
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF126P1 ring finger protein 126 pseudogene 1
RPL13P5 ribosomal protein L13 pseudogene 5
SAMD9 sterile alpha motif domain containing 9
SDC3 syndecan 3
SERGEF secretion regulating guanine nucleotide exchange factor
SIRT2 sirtuin 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35F5 solute carrier family 35, member F5
SOWAHC sosondowah ankyrin repeat domain family member C
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
SREK1IP1 SREK1-interacting protein 1
TAGLN3 transgelin 3
TBX19 T-box 19
TMEM120B transmembrane protein 120B
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRIP10 thyroid hormone receptor interactor 10
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USP19 ubiquitin specific peptidase 19
VASH1 vasohibin 1
VEGFB vascular endothelial growth factor B
VNN2 vanin 2
ZFP37 ZFP37 zinc finger protein
ZNF134 zinc finger protein 134
ZNF250 zinc finger protein 250
ZNF350 zinc finger protein 350
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747
ZNRD1-AS1 ZNRD1 antisense RNA 1