tribenoside-2946 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tribenoside-2946 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ACACB acetyl-CoA carboxylase beta
ADAMDEC1 ADAM-like, decysin 1
AGER advanced glycosylation end product-specific receptor
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
AREG amphiregulin
ARL4C ADP-ribosylation factor-like 4C
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
AXL AXL receptor tyrosine kinase
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BIN1 bridging integrator 1
BMP6 bone morphogenetic protein 6
C19ORF66 chromosome 19 open reading frame 66
CAPN10 calpain 10
CBX8 chromobox homolog 8
CCL20 chemokine (C-C motif) ligand 20
CCRL2 chemokine (C-C motif) receptor-like 2
CD86 CD86 molecule
CDC14A cell division cycle 14A
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CECR1 cat eye syndrome chromosome region, candidate 1
CEP164 centrosomal protein 164kDa
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CREM cAMP responsive element modulator
CXCL10 chemokine (C-X-C motif) ligand 10
DDAH2 dimethylarginine dimethylaminohydrolase 2
DEAF1 DEAF1 transcription factor
DNPEP aspartyl aminopeptidase
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
DVL1 dishevelled segment polarity protein 1
EFNA4 ephrin-A4
ELMO3 engulfment and cell motility 3
FADS3 fatty acid desaturase 3
FAM13A family with sequence similarity 13, member A
FBRS fibrosin
FGF2 fibroblast growth factor 2 (basic)
FTH1 ferritin, heavy polypeptide 1
GOLGA8A golgin A8 family, member A
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
ICOSLG inducible T-cell co-stimulator ligand
IL1B interleukin 1, beta
IL24 interleukin 24
ISG15 ISG15 ubiquitin-like modifier
ITGB4 integrin, beta 4
JAG1 jagged 1
KYNU kynureninase
MAPK7 mitogen-activated protein kinase 7
MCTP2 multiple C2 domains, transmembrane 2
MED14 mediator complex subunit 14
MEF2C myocyte enhancer factor 2C
MICALL1 MICAL-like 1
MIR22HG MIR22 host gene
MR1 major histocompatibility complex, class I-related
MTA1 metastasis associated 1
MUC1 mucin 1, cell surface associated
MXD3 MAX dimerization protein 3
NABP1 nucleic acid binding protein 1
NAMPT nicotinamide phosphoribosyltransferase
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRCAM neuronal cell adhesion molecule
NRP1 neuropilin 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM2 PDZ and LIM domain 2 (mystique)
PLCG1 phospholipase C, gamma 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRKCZ protein kinase C, zeta
PTEN phosphatase and tensin homolog
PYGB phosphorylase, glycogen; brain
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RPL35A ribosomal protein L35a
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMG5 SMG5 nonsense mediated mRNA decay factor
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TBC1D17 TBC1 domain family, member 17
TGM5 transglutaminase 5
THBS1 thrombospondin 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNIK TRAF2 and NCK interacting kinase
TNS1 tensin 1
TPM1 tropomyosin 1 (alpha)
TRAPPC9 trafficking protein particle complex 9
TTC38 tetratricopeptide repeat domain 38
TTLL3 tubulin tyrosine ligase-like family member 3
ULK2 unc-51 like autophagy activating kinase 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WAPAL wings apart-like homolog (Drosophila)
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF345 zinc finger protein 345

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACOX2 acyl-CoA oxidase 2, branched chain
ADAM15 ADAM metallopeptidase domain 15
ADAM23 ADAM metallopeptidase domain 23
ADRB2 adrenoceptor beta 2, surface
AEN apoptosis enhancing nuclease
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAG4 BCL2-associated athanogene 4
BAMBI BMP and activin membrane-bound inhibitor
C10ORF2 chromosome 10 open reading frame 2
C14ORF159 chromosome 14 open reading frame 159
CCDC186 coiled-coil domain containing 186
CCL27 chemokine (C-C motif) ligand 27
CD1D CD1d molecule
CD320 CD320 molecule
CEP97 centrosomal protein 97kDa
CES3 carboxylesterase 3
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNR2 cannabinoid receptor 2 (macrophage)
CORO2A coronin, actin binding protein, 2A
CORO7 coronin 7
CRYL1 crystallin, lambda 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBIP1 catenin, beta interacting protein 1
DDRGK1 DDRGK domain containing 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGKG diacylglycerol kinase, gamma 90kDa
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNMBP dynamin binding protein
ECSIT ECSIT signalling integrator
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERCC6L excision repair cross-complementation group 6-like
FAM53B family with sequence similarity 53, member B
FBXL7 F-box and leucine-rich repeat protein 7
FHL3 four and a half LIM domains 3
FOSL1 FOS-like antigen 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GMPPB GDP-mannose pyrophosphorylase B
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HDAC9 histone deacetylase 9
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HP haptoglobin
HPSE heparanase
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IDI2-AS1 IDI2 antisense RNA 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INF2 inverted formin, FH2 and WH2 domain containing
IRS1 insulin receptor substrate 1
ITGA10 integrin, alpha 10
JMJD4 jumonji domain containing 4
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCTD20 potassium channel tetramerization domain containing 20
KLK5 kallikrein-related peptidase 5
KPTN kaptin (actin binding protein)
LINS lines homolog (Drosophila)
LZTS3 leucine zipper, putative tumor suppressor family member 3
METTL2B methyltransferase like 2B
MMP2 matrix metallopeptidase 2
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTCP1 mature T-cell proliferation 1
NDE1 nudE neurodevelopment protein 1
NKX3-2 NK3 homeobox 2
NLRX1 NLR family member X1
NT5M 5',3'-nucleotidase, mitochondrial
ODF2 outer dense fiber of sperm tails 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
QSER1 glutamine and serine rich 1
RABL6 RAB, member RAS oncogene family-like 6
RNF167 ring finger protein 167
RPP25 ribonuclease P/MRP 25kDa subunit
SIRAL2 SIR2 antiphage like 2
SLC12A9 solute carrier family 12, member 9
SMYD5 SMYD family member 5
SPATA20 spermatogenesis associated 20
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STARD13 StAR-related lipid transfer (START) domain containing 13
SURF2 surfeit 2
TCTA T-cell leukemia translocation altered
TESK1 testis-specific kinase 1
THEM6 thioesterase superfamily member 6
TMOD3 tropomodulin 3 (ubiquitous)
TRAF1 TNF receptor-associated factor 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBP1 upstream binding protein 1 (LBP-1a)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR33 WD repeat domain 33
XKR8 XK, Kell blood group complex subunit-related family, member 8
YIPF1 Yip1 domain family, member 1
ZNF493 zinc finger protein 493
ZNF574 zinc finger protein 574