tribenoside-3507 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tribenoside-3507 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ADAM17 ADAM metallopeptidase domain 17
ADAM22 ADAM metallopeptidase domain 22
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ALK anaplastic lymphoma receptor tyrosine kinase
APOE apolipoprotein E
ART1 ADP-ribosyltransferase 1
ATF3 activating transcription factor 3
AUTS2 autism susceptibility candidate 2
BCAM basal cell adhesion molecule (Lutheran blood group)
BGN biglycan
BIRC3 baculoviral IAP repeat containing 3
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CD37 CD37 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DCTN2 dynactin 2 (p50)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DSC3 desmocollin 3
EML2 echinoderm microtubule associated protein like 2
ETV5 ets variant 5
EXPH5 exophilin 5
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM131A family with sequence similarity 131, member A
FASLG Fas ligand (TNF superfamily, member 6)
FN1 fibronectin 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FYB FYN binding protein
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GRB10 growth factor receptor-bound protein 10
GSK3A glycogen synthase kinase 3 alpha
HABP2 hyaluronan binding protein 2
HAMP hepcidin antimicrobial peptide
HEG1 heart development protein with EGF-like domains 1
IDS iduronate 2-sulfatase
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA17 interferon, alpha 17
IL11 interleukin 11
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL36RN interleukin 36 receptor antagonist
INHBE inhibin, beta E
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0485 uncharacterized LOC57235
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT75 keratin 75, type II
LINC00341 long intergenic non-protein coding RNA 341
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MFGE8 milk fat globule-EGF factor 8 protein
MNMIP1 manchette microtubule inner protein 1
MTMR7 myotubularin related protein 7
NEUROD1 neuronal differentiation 1
NF2 neurofibromin 2 (merlin)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NIN ninein (GSK3B interacting protein)
NOL10 nucleolar protein 10
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
OTOR otoraplin
PLAU plasminogen activator, urokinase
POU2F2 POU class 2 homeobox 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTX3 pentraxin 3, long
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RECQL5 RecQ protein-like 5
RGS12 regulator of G-protein signaling 12
RND1 Rho family GTPase 1
RNF208 ring finger protein 208
RRH retinal pigment epithelium-derived rhodopsin homolog
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLIT1 slit homolog 1 (Drosophila)
SOX10 SRY (sex determining region Y)-box 10
SP2 Sp2 transcription factor
SRSF7 serine/arginine-rich splicing factor 7
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAT tyrosine aminotransferase
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFEB transcription factor EB
TK2 thymidine kinase 2, mitochondrial
TLR2 toll-like receptor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNS2 tensin 2
TOP3B topoisomerase (DNA) III beta
TTLL4 tubulin tyrosine ligase-like family member 4
VEGFA vascular endothelial growth factor A
VIPR2 vasoactive intestinal peptide receptor 2
WAS Wiskott-Aldrich syndrome
ZNF287 zinc finger protein 287
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADAM15 ADAM metallopeptidase domain 15
ADGRG2 adhesion G protein-coupled receptor G2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
APOLD1 apolipoprotein L domain containing 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARRB1 arrestin, beta 1
BAHCC1 BAH domain and coiled-coil containing 1
BMP4 bone morphogenetic protein 4
C10ORF95 chromosome 10 open reading frame 95
C19ORF40 chromosome 19 open reading frame 40
C19ORF73 chromosome 19 open reading frame 73
CAPN15 calpain 15
CCDC85C coiled-coil domain containing 85C
CEP131 centrosomal protein 131kDa
CLDN4 claudin 4
CTSK cathepsin K
CXCR2 chemokine (C-X-C motif) receptor 2
CYBA cytochrome b-245, alpha polypeptide
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
EFNA3 ephrin-A3
EGLN3 egl-9 family hypoxia-inducible factor 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA2 EPH receptor A2
ERCC6L excision repair cross-complementation group 6-like
ERI3 ERI1 exoribonuclease family member 3
ESRP2 epithelial splicing regulatory protein 2
EVPL envoplakin
F3 coagulation factor III (thromboplastin, tissue factor)
FAM46C family with sequence similarity 46, member C
FBXL6 F-box and leucine-rich repeat protein 6
FGF23 fibroblast growth factor 23
GBP2 guanylate binding protein 2, interferon-inducible
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLCE glucuronic acid epimerase
GPATCH2L G patch domain containing 2-like
GPX2 glutathione peroxidase 2
GTPBP6 GTP binding protein 6 (putative)
HIST1H1D histone cluster 1, H1d
HOXC11 homeobox C11
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IDI2-AS1 IDI2 antisense RNA 1
IGFBP6 insulin-like growth factor binding protein 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCTD20 potassium channel tetramerization domain containing 20
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIME1 Lck interacting transmembrane adaptor 1
LIN7A lin-7 homolog A (C. elegans)
LMNB2 lamin B2
LYPD1 LY6/PLAUR domain containing 1
MBIP MAP3K12 binding inhibitory protein 1
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MITF microphthalmia-associated transcription factor
MMP9 matrix metallopeptidase 9
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NPTX1 neuronal pentraxin I
P3H1 prolyl 3-hydroxylase 1
PC pyruvate carboxylase
PDLIM2 PDZ and LIM domain 2 (mystique)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLD3 phospholipase D family, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
POU2F1 POU class 2 homeobox 1
PPOX protoporphyrinogen oxidase
PROCR protein C receptor, endothelial
PROS1 protein S (alpha)
PRSS22 protease, serine, 22
RAB4B RAB4B, member RAS oncogene family
RLN1 relaxin 1
ROM1 retinal outer segment membrane protein 1
S100A4 S100 calcium binding protein A4
SCAI suppressor of cancer cell invasion
SIRT6 sirtuin 6
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SRD5A3 steroid 5 alpha-reductase 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STXBP2 syntaxin binding protein 2
TBX19 T-box 19
TCP10 t-complex 10
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TOM1 target of myb1 (chicken)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBXN6 UBX domain protein 6
USB1 U6 snRNA biogenesis 1
XYLT2 xylosyltransferase II
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668
ZNF696 zinc finger protein 696
ZSCAN5A zinc finger and SCAN domain containing 5A