tribenoside-6328 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tribenoside-6328 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
BMP7 bone morphogenetic protein 7
BTN3A3 butyrophilin, subfamily 3, member A3
C21ORF2 chromosome 21 open reading frame 2
C5ORF42 chromosome 5 open reading frame 42
C7ORF69 chromosome 7 open reading frame 69
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CD82 CD82 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL10A1 collagen, type X, alpha 1
CSNK1E casein kinase 1, epsilon
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEF6 differentially expressed in FDCP 6 homolog (mouse)
E2F4 E2F transcription factor 4, p107/p130-binding
EFNA3 ephrin-A3
EIF1 eukaryotic translation initiation factor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELMO3 engulfment and cell motility 3
EMP1 epithelial membrane protein 1
EMX1 empty spiracles homeobox 1
FAM13A family with sequence similarity 13, member A
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGL1 fibrinogen-like 1
FH fumarate hydratase
FLOT2 flotillin 2
FOXO1 forkhead box O1
FRMPD1 FERM and PDZ domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GFER growth factor, augmenter of liver regeneration
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GK glycerol kinase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPC1 glypican 1
GPR183 G protein-coupled receptor 183
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIST1H2AB histone cluster 1, H2ab
HOXC10 homeobox C10
IFI44 interferon-induced protein 44
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL6 interleukin 6
IL7 interleukin 7
KDM6B lysine (K)-specific demethylase 6B
KIAA1107 KIAA1107
KLF12 Kruppel-like factor 12
KLF13 Kruppel-like factor 13
KRT20 keratin 20, type I
KRT31 keratin 31, type I
KRT4 keratin 4, type II
KYNU kynureninase
LHX2 LIM homeobox 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMTK1 lemur tail kinase 1
LTC4S leukotriene C4 synthase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MINK1 misshapen-like kinase 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC3A mucin 3A, cell surface associated
NAG18 NAG18 mRNA
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NOX1 NADPH oxidase 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
PHF20 PHD finger protein 20
PIDD1 p53-induced death domain protein 1
PRB1 proline-rich protein BstNI subfamily 1
PVR poliovirus receptor
RGS4 regulator of G-protein signaling 4
RHOQ ras homolog family member Q
RIN3 Ras and Rab interactor 3
SCN9A sodium channel, voltage gated, type IX alpha subunit
SLCO1B1 solute carrier organic anion transporter family, member 1B1
TGFBI transforming growth factor, beta-induced, 68kDa
THRA thyroid hormone receptor, alpha
TMEM212 transmembrane protein 212
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TSC2 tuberous sclerosis 2
U2SURP U2 snRNP-associated SURP domain containing
UHRF1BP1L UHRF1 binding protein 1-like
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VGF VGF nerve growth factor inducible
VIPR2 vasoactive intestinal peptide receptor 2
VLDLR very low density lipoprotein receptor
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
ZBTB1 zinc finger and BTB domain containing 1
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRG2 adhesion G protein-coupled receptor G2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGAP10 Rho GTPase activating protein 10
ARMC6 armadillo repeat containing 6
ATAD2B ATPase family, AAA domain containing 2B
AUH AU RNA binding protein/enoyl-CoA hydratase
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEND5 BEN domain containing 5
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BPHL biphenyl hydrolase-like (serine hydrolase)
C1ORF159 chromosome 1 open reading frame 159
CCDC176 coiled-coil domain containing 176
CIR1 corepressor interacting with RBPJ, 1
CLDN11 claudin 11
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSRNP3 cysteine-serine-rich nuclear protein 3
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DLL3 delta-like 3 (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
FAM69A family with sequence similarity 69, member A
FANCE Fanconi anemia, complementation group E
FBXL7 F-box and leucine-rich repeat protein 7
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF13 fibroblast growth factor 13
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCHFR GTP cyclohydrolase I feedback regulator
GJC1 gap junction protein, gamma 1, 45kDa
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2I general transcription factor IIi
HDAC5 histone deacetylase 5
HIST1H3G histone cluster 1, H3g
HOOK2 hook microtubule-tethering protein 2
HOXA4 homeobox A4
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INO80D INO80 complex subunit D
LHFPL2 lipoma HMGIC fusion partner-like 2
LINC00341 long intergenic non-protein coding RNA 341
LPPR4 lipid phosphate phosphatase-related protein type 4
LYPD1 LY6/PLAUR domain containing 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MECR mitochondrial trans-2-enoyl-CoA reductase
MPP1 membrane protein, palmitoylated 1, 55kDa
MRPL28 mitochondrial ribosomal protein L28
MRPS34 mitochondrial ribosomal protein S34
MT1HL1 metallothionein 1H-like 1
NECAP1 NECAP endocytosis associated 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NNT nicotinamide nucleotide transhydrogenase
NPM3 nucleophosmin/nucleoplasmin 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PADI1 peptidyl arginine deiminase, type I
PCSK7 proprotein convertase subtilisin/kexin type 7
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCD1 phospholipase C, delta 1
PPT2 palmitoyl-protein thioesterase 2
PSAT1 phosphoserine aminotransferase 1
RABL6 RAB, member RAS oncogene family-like 6
RFX7 regulatory factor X, 7
RNF146 ring finger protein 146
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A4 S100 calcium binding protein A4
SCG5 secretogranin V
SDF2 stromal cell-derived factor 2
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD6 SET domain containing 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPAG1 sperm associated antigen 1
SPAG4 sperm associated antigen 4
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TASP1 taspase, threonine aspartase, 1
TESK2 testis-specific kinase 2
TM6SF1 transmembrane 6 superfamily member 1
TMEM156 transmembrane protein 156
TRIM21 tripartite motif containing 21
TSPAN1 tetraspanin 1
UEVLD UEV and lactate/malate dehyrogenase domains
USP19 ubiquitin specific peptidase 19
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR18 WD repeat domain 18
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF264 zinc finger protein 264
ZNF34 zinc finger protein 34
ZNF385D zinc finger protein 385D
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862