Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the trichostatin A-1421 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACP6 | acid phosphatase 6, lysophosphatidic |
ADD3 | adducin 3 (gamma) |
ADRBK2 | adrenergic, beta, receptor kinase 2 |
ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
ARID5B | AT rich interactive domain 5B (MRF1-like) |
ARL3 | ADP-ribosylation factor-like 3 |
ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
ASMTL | acetylserotonin O-methyltransferase-like |
ATG2A | autophagy related 2A |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
BAG3 | BCL2-associated athanogene 3 |
CCS | copper chaperone for superoxide dismutase |
CD59 | CD59 molecule, complement regulatory protein |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CLEC2B | C-type lectin domain family 2, member B |
CPM | carboxypeptidase M |
CREB3 | cAMP responsive element binding protein 3 |
CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
DSE | dermatan sulfate epimerase |
DUSP6 | dual specificity phosphatase 6 |
DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
ECI2 | enoyl-CoA delta isomerase 2 |
EFNA4 | ephrin-A4 |
EPAS1 | endothelial PAS domain protein 1 |
ERAP2 | endoplasmic reticulum aminopeptidase 2 |
EXPH5 | exophilin 5 |
EXTL2 | exostosin-like glycosyltransferase 2 |
F11R | F11 receptor |
FAM49A | family with sequence similarity 49, member A |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
FIG4 | FIG4 phosphoinositide 5-phosphatase |
FUCA1 | fucosidase, alpha-L- 1, tissue |
GCH1 | GTP cyclohydrolase 1 |
GLTP | glycolipid transfer protein |
GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
GPSM2 | G-protein signaling modulator 2 |
GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa |
HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
HOOK2 | hook microtubule-tethering protein 2 |
HRSP12 | heat-responsive protein 12 |
IFI16 | interferon, gamma-inducible protein 16 |
ITGA7 | integrin, alpha 7 |
ITSN1 | intersectin 1 (SH3 domain protein) |
KHK | ketohexokinase (fructokinase) |
KIF5C | kinesin family member 5C |
LHB | luteinizing hormone beta polypeptide |
LPIN1 | lipin 1 |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MARK4 | MAP/microtubule affinity-regulating kinase 4 |
MCOLN1 | mucolipin 1 |
METTL7A | methyltransferase like 7A |
MPZL1 | myelin protein zero-like 1 |
MTMR3 | myotubularin related protein 3 |
MTSS1 | metastasis suppressor 1 |
N4BP1 | NEDD4 binding protein 1 |
NME7 | NME/NM23 family member 7 |
NQO2 | NAD(P)H dehydrogenase, quinone 2 |
PCGF2 | polycomb group ring finger 2 |
PCNXL2 | pecanex-like 2 (Drosophila) |
PCSK7 | proprotein convertase subtilisin/kexin type 7 |
PIDD1 | p53-induced death domain protein 1 |
PITPNA | phosphatidylinositol transfer protein, alpha |
PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
PRAF2 | PRA1 domain family, member 2 |
RGS2 | regulator of G-protein signaling 2 |
RHOC | ras homolog family member C |
RPAP2 | RNA polymerase II associated protein 2 |
RPL13P5 | ribosomal protein L13 pseudogene 5 |
RTN2 | reticulon 2 |
SATB1 | SATB homeobox 1 |
SCAPER | S-phase cyclin A-associated protein in the ER |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SSBP2 | single-stranded DNA binding protein 2 |
STAC | SH3 and cysteine rich domain |
STXBP1 | syntaxin binding protein 1 |
TM7SF2 | transmembrane 7 superfamily member 2 |
TP53BP1 | tumor protein p53 binding protein 1 |
TPBG | trophoblast glycoprotein |
TSPAN13 | tetraspanin 13 |
TTC13 | tetratricopeptide repeat domain 13 |
TTLL4 | tubulin tyrosine ligase-like family member 4 |
TUBB2A | tubulin, beta 2A class IIa |
TUFT1 | tuftelin 1 |
WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
ZC2HC1A | zinc finger, C2HC-type containing 1A |
ZSWIM8 | zinc finger, SWIM-type containing 8 |
Symbol | Name |
---|---|
ACSL4 | acyl-CoA synthetase long-chain family member 4 |
ACSL5 | acyl-CoA synthetase long-chain family member 5 |
ADI1 | acireductone dioxygenase 1 |
ASB13 | ankyrin repeat and SOCS box containing 13 |
AZI2 | 5-azacytidine induced 2 |
BRIX1 | BRX1, biogenesis of ribosomes |
C5ORF28 | chromosome 5 open reading frame 28 |
CARD9 | caspase recruitment domain family, member 9 |
CASD1 | CAS1 domain containing 1 |
CASZ1 | castor zinc finger 1 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCL2 | chemokine (C-C motif) ligand 2 |
CD14 | CD14 molecule |
CLEC5A | C-type lectin domain family 5, member A |
CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
CNPY3 | canopy FGF signaling regulator 3 |
CTDNEP1 | CTD nuclear envelope phosphatase 1 |
CXORF21 | chromosome X open reading frame 21 |
DCPS | decapping enzyme, scavenger |
DCTN4 | dynactin 4 (p62) |
DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
DKC1 | dyskeratosis congenita 1, dyskerin |
DTWD1 | DTW domain containing 1 |
ERF | Ets2 repressor factor |
FAM136A | family with sequence similarity 136, member A |
FAM216A | family with sequence similarity 216, member A |
FANCF | Fanconi anemia, complementation group F |
FES | FES proto-oncogene, tyrosine kinase |
FMNL1 | formin-like 1 |
FXN | frataxin |
GPR183 | G protein-coupled receptor 183 |
GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
HMHA1 | histocompatibility (minor) HA-1 |
HP | haptoglobin |
IFRD2 | interferon-related developmental regulator 2 |
IMPACT | impact RWD domain protein |
ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
KCTD15 | potassium channel tetramerization domain containing 15 |
KLHL21 | kelch-like family member 21 |
LAMP5 | lysosomal-associated membrane protein family, member 5 |
LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) |
LBR | lamin B receptor |
LMNB1 | lamin B1 |
MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
MAGOHB | mago-nashi homolog B (Drosophila) |
MEPCE | methylphosphate capping enzyme |
MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) |
MNT | MAX network transcriptional repressor |
MORC3 | MORC family CW-type zinc finger 3 |
MPDU1 | mannose-P-dolichol utilization defect 1 |
MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NECAB3 | N-terminal EF-hand calcium binding protein 3 |
NIP7 | NIP7, nucleolar pre-rRNA processing protein |
NMI | N-myc (and STAT) interactor |
NOD1 | nucleotide-binding oligomerization domain containing 1 |
NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor |
PAK1IP1 | PAK1 interacting protein 1 |
PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
PCF11 | PCF11 cleavage and polyadenylation factor subunit |
PEF1 | penta-EF-hand domain containing 1 |
PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
PMF1 | polyamine-modulated factor 1 |
PRMT3 | protein arginine methyltransferase 3 |
PRPF39 | pre-mRNA processing factor 39 |
PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
PUS1 | pseudouridylate synthase 1 |
PUS7 | pseudouridylate synthase 7 (putative) |
RGS19 | regulator of G-protein signaling 19 |
RNH1 | ribonuclease/angiogenin inhibitor 1 |
RP2 | retinitis pigmentosa 2 (X-linked recessive) |
RPS14P3 | ribosomal protein S14 pseudogene 3 |
RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
SARS2 | seryl-tRNA synthetase 2, mitochondrial |
SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
SEH1L | SEH1-like (S. cerevisiae) |
SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
SNHG3 | small nucleolar RNA host gene 3 |
SPI1 | Spi-1 proto-oncogene |
ST7 | suppression of tumorigenicity 7 |
STXBP3 | syntaxin binding protein 3 |
TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
TOE1 | target of EGR1, member 1 (nuclear) |
TPRA1 | transmembrane protein, adipocyte asscociated 1 |
TTC27 | tetratricopeptide repeat domain 27 |
UBIAD1 | UbiA prenyltransferase domain containing 1 |
UNG | uracil-DNA glycosylase |
URGCP | upregulator of cell proliferation |
UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
WDR43 | WD repeat domain 43 |
WDR5B | WD repeat domain 5B |
XPOT | exportin, tRNA |
YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
ZEB2 | zinc finger E-box binding homeobox 2 |
ZNF140 | zinc finger protein 140 |
ZNF408 | zinc finger protein 408 |