Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the trichostatin A-1561 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABI2 | abl-interactor 2 |
ACP6 | acid phosphatase 6, lysophosphatidic |
ADD3 | adducin 3 (gamma) |
AGFG1 | ArfGAP with FG repeats 1 |
AGRP | agouti related neuropeptide |
AHR | aryl hydrocarbon receptor |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
ASMTL | acetylserotonin O-methyltransferase-like |
ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
BCL6 | B-cell CLL/lymphoma 6 |
C19ORF66 | chromosome 19 open reading frame 66 |
CACYBP | calcyclin binding protein |
CANT1 | calcium activated nucleotidase 1 |
CAST | calpastatin |
CCL20 | chemokine (C-C motif) ligand 20 |
CCS | copper chaperone for superoxide dismutase |
CCSER2 | coiled-coil serine-rich protein 2 |
CD59 | CD59 molecule, complement regulatory protein |
CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
CREB3 | cAMP responsive element binding protein 3 |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
CYLD | cylindromatosis (turban tumor syndrome) |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DAAM1 | dishevelled associated activator of morphogenesis 1 |
DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
DPYD | dihydropyrimidine dehydrogenase |
DSE | dermatan sulfate epimerase |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
ECI2 | enoyl-CoA delta isomerase 2 |
ELMO2 | engulfment and cell motility 2 |
ENO2 | enolase 2 (gamma, neuronal) |
EPAS1 | endothelial PAS domain protein 1 |
EPS8 | epidermal growth factor receptor pathway substrate 8 |
EVI5 | ecotropic viral integration site 5 |
F11R | F11 receptor |
FAM13A | family with sequence similarity 13, member A |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
FGFR1 | fibroblast growth factor receptor 1 |
FIG4 | FIG4 phosphoinositide 5-phosphatase |
FUCA1 | fucosidase, alpha-L- 1, tissue |
GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
GCH1 | GTP cyclohydrolase 1 |
GPR65 | G protein-coupled receptor 65 |
GPSM3 | G-protein signaling modulator 3 |
HCAR3 | hydroxycarboxylic acid receptor 3 |
HDAC5 | histone deacetylase 5 |
HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
HTATSF1 | HIV-1 Tat specific factor 1 |
HTT | huntingtin |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IFI16 | interferon, gamma-inducible protein 16 |
INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
JRKL | JRK-like |
JUN | jun proto-oncogene |
KDM5A | lysine (K)-specific demethylase 5A |
LAD1 | ladinin 1 |
LMAN2L | lectin, mannose-binding 2-like |
LTA4H | leukotriene A4 hydrolase |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MARK4 | MAP/microtubule affinity-regulating kinase 4 |
MCL1 | myeloid cell leukemia 1 |
METTL7A | methyltransferase like 7A |
MMP2 | matrix metallopeptidase 2 |
NCOA3 | nuclear receptor coactivator 3 |
NME7 | NME/NM23 family member 7 |
NMRK1 | nicotinamide riboside kinase 1 |
OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
PCGF2 | polycomb group ring finger 2 |
PCNXL2 | pecanex-like 2 (Drosophila) |
PCSK7 | proprotein convertase subtilisin/kexin type 7 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
PLS1 | plastin 1 |
PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
PRDM2 | PR domain containing 2, with ZNF domain |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PTK2 | protein tyrosine kinase 2 |
PTX3 | pentraxin 3, long |
QPCT | glutaminyl-peptide cyclotransferase |
RABAC1 | Rab acceptor 1 (prenylated) |
RPL13P5 | ribosomal protein L13 pseudogene 5 |
RRAGD | Ras-related GTP binding D |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STXBP1 | syntaxin binding protein 1 |
SWAP70 | SWAP switching B-cell complex 70kDa subunit |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TPBG | trophoblast glycoprotein |
TPD52L1 | tumor protein D52-like 1 |
TPM1 | tropomyosin 1 (alpha) |
TSPAN13 | tetraspanin 13 |
TUFT1 | tuftelin 1 |
TUSC2 | tumor suppressor candidate 2 |
WDR48 | WD repeat domain 48 |
Symbol | Name |
---|---|
ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
ADI1 | acireductone dioxygenase 1 |
ALPK1 | alpha-kinase 1 |
ARFGAP2 | ADP-ribosylation factor GTPase activating protein 2 |
ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
C4ORF29 | chromosome 4 open reading frame 29 |
CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
CAMTA2 | calmodulin binding transcription activator 2 |
CARD9 | caspase recruitment domain family, member 9 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CBS | cystathionine-beta-synthase |
CCDC130 | coiled-coil domain containing 130 |
CDC23 | cell division cycle 23 |
CEND1 | cell cycle exit and neuronal differentiation 1 |
CER1 | cerberus 1, DAN family BMP antagonist |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CIDEB | cell death-inducing DFFA-like effector b |
CISH | cytokine inducible SH2-containing protein |
CNOT6 | CCR4-NOT transcription complex, subunit 6 |
CNPY3 | canopy FGF signaling regulator 3 |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
FAM136A | family with sequence similarity 136, member A |
FAM50B | family with sequence similarity 50, member B |
FAM53B | family with sequence similarity 53, member B |
FAN1 | FANCD2/FANCI-associated nuclease 1 |
FMNL1 | formin-like 1 |
GALNS | galactosamine (N-acetyl)-6-sulfatase |
GATAD2A | GATA zinc finger domain containing 2A |
GCN1L1 | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) |
GGTLC1 | gamma-glutamyltransferase light chain 1 |
GPR27 | G protein-coupled receptor 27 |
GRAMD4 | GRAM domain containing 4 |
GUSBP3 | glucuronidase, beta pseudogene 3 |
IFRD2 | interferon-related developmental regulator 2 |
INO80D | INO80 complex subunit D |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
KAT2A | K(lysine) acetyltransferase 2A |
KIAA0196 | KIAA0196 |
KIAA0894 | KIAA0894 protein |
KIAA1551 | KIAA1551 |
KLHL21 | kelch-like family member 21 |
LARP1 | La ribonucleoprotein domain family, member 1 |
LRP5L | low density lipoprotein receptor-related protein 5-like |
MAPK12 | mitogen-activated protein kinase 12 |
MATK | megakaryocyte-associated tyrosine kinase |
MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
MOGS | mannosyl-oligosaccharide glucosidase |
MRPS27 | mitochondrial ribosomal protein S27 |
MTM1 | myotubularin 1 |
MUC3A | mucin 3A, cell surface associated |
NHEJ1 | nonhomologous end-joining factor 1 |
NUCB2 | nucleobindin 2 |
PAK1IP1 | PAK1 interacting protein 1 |
PEMT | phosphatidylethanolamine N-methyltransferase |
PES1 | pescadillo ribosomal biogenesis factor 1 |
PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
PNRC1 | proline-rich nuclear receptor coactivator 1 |
PODNL1 | podocan-like 1 |
POTEKP | POTE ankyrin domain family, member K, pseudogene |
PRMT3 | protein arginine methyltransferase 3 |
PTGES2 | prostaglandin E synthase 2 |
PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
PUS7 | pseudouridylate synthase 7 (putative) |
PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
PYCR1 | pyrroline-5-carboxylate reductase 1 |
RNF44 | ring finger protein 44 |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
SCO2 | SCO2 cytochrome c oxidase assembly protein |
SEH1L | SEH1-like (S. cerevisiae) |
SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) |
SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
SNHG3 | small nucleolar RNA host gene 3 |
SNX17 | sorting nexin 17 |
SPAG7 | sperm associated antigen 7 |
SPON2 | spondin 2, extracellular matrix protein |
STEAP3 | STEAP family member 3, metalloreductase |
SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
TBL3 | transducin (beta)-like 3 |
TEFM | transcription elongation factor, mitochondrial |
TERT | telomerase reverse transcriptase |
TLN1 | talin 1 |
TOP2B | topoisomerase (DNA) II beta 180kDa |
TPCN1 | two pore segment channel 1 |
UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
WDR74 | WD repeat domain 74 |
WDR82 | WD repeat domain 82 |
XPOT | exportin, tRNA |
ZNF282 | zinc finger protein 282 |