Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the trichostatin A-1612 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AAMDC | adipogenesis associated, Mth938 domain containing |
ABHD3 | abhydrolase domain containing 3 |
ACP6 | acid phosphatase 6, lysophosphatidic |
ADD3 | adducin 3 (gamma) |
ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
ATP10D | ATPase, class V, type 10D |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
ATR | ATR serine/threonine kinase |
BAD | BCL2-associated agonist of cell death |
BIN1 | bridging integrator 1 |
BLVRB | biliverdin reductase B |
C16ORF58 | chromosome 16 open reading frame 58 |
C19ORF66 | chromosome 19 open reading frame 66 |
CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
CCL20 | chemokine (C-C motif) ligand 20 |
CCSER2 | coiled-coil serine-rich protein 2 |
CD59 | CD59 molecule, complement regulatory protein |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CEP68 | centrosomal protein 68kDa |
CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
CREB3 | cAMP responsive element binding protein 3 |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
CYB5A | cytochrome b5 type A (microsomal) |
DFNA5 | deafness, autosomal dominant 5 |
DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
ECI2 | enoyl-CoA delta isomerase 2 |
ENAH | enabled homolog (Drosophila) |
EPAS1 | endothelial PAS domain protein 1 |
EXT2 | exostosin glycosyltransferase 2 |
EXTL2 | exostosin-like glycosyltransferase 2 |
F11R | F11 receptor |
FAM49A | family with sequence similarity 49, member A |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
FGFR1 | fibroblast growth factor receptor 1 |
FUCA1 | fucosidase, alpha-L- 1, tissue |
GBAP1 | glucosidase, beta, acid pseudogene 1 |
GCA | grancalcin, EF-hand calcium binding protein |
GGCX | gamma-glutamyl carboxylase |
GPSM2 | G-protein signaling modulator 2 |
GSTM4 | glutathione S-transferase mu 4 |
IFI16 | interferon, gamma-inducible protein 16 |
INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
ITM2C | integral membrane protein 2C |
KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 |
KIF5C | kinesin family member 5C |
KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
KLF13 | Kruppel-like factor 13 |
LPAR6 | lysophosphatidic acid receptor 6 |
LTA4H | leukotriene A4 hydrolase |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MARK4 | MAP/microtubule affinity-regulating kinase 4 |
MBNL2 | muscleblind-like splicing regulator 2 |
MCAM | melanoma cell adhesion molecule |
MEF2C | myocyte enhancer factor 2C |
MEGF9 | multiple EGF-like-domains 9 |
METTL7A | methyltransferase like 7A |
MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
MOB3B | MOB kinase activator 3B |
MOSPD2 | motile sperm domain containing 2 |
MPZL1 | myelin protein zero-like 1 |
MTSS1 | metastasis suppressor 1 |
NDE1 | nudE neurodevelopment protein 1 |
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
NMRK1 | nicotinamide riboside kinase 1 |
PCNXL2 | pecanex-like 2 (Drosophila) |
PCSK7 | proprotein convertase subtilisin/kexin type 7 |
PFN2 | profilin 2 |
PICALM | phosphatidylinositol binding clathrin assembly protein |
PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
PLA2G12A | phospholipase A2, group XIIA |
PLS1 | plastin 1 |
PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PTX3 | pentraxin 3, long |
RAB28 | RAB28, member RAS oncogene family |
RAB31 | RAB31, member RAS oncogene family |
RABAC1 | Rab acceptor 1 (prenylated) |
RARS | arginyl-tRNA synthetase |
RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
RIOK3 | RIO kinase 3 |
RNGTT | RNA guanylyltransferase and 5'-phosphatase |
SAR1B | secretion associated, Ras related GTPase 1B |
SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
SOAT1 | sterol O-acyltransferase 1 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STXBP1 | syntaxin binding protein 1 |
TPD52L1 | tumor protein D52-like 1 |
TPR | translocated promoter region, nuclear basket protein |
TRIB2 | tribbles pseudokinase 2 |
TSPAN13 | tetraspanin 13 |
TUFT1 | tuftelin 1 |
WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
ZFYVE16 | zinc finger, FYVE domain containing 16 |
Symbol | Name |
---|---|
ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
ACSL5 | acyl-CoA synthetase long-chain family member 5 |
ADI1 | acireductone dioxygenase 1 |
AVEN | apoptosis, caspase activation inhibitor |
C10ORF2 | chromosome 10 open reading frame 2 |
C17ORF70 | chromosome 17 open reading frame 70 |
C1ORF174 | chromosome 1 open reading frame 174 |
C9ORF40 | chromosome 9 open reading frame 40 |
CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
CARD9 | caspase recruitment domain family, member 9 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCDC9 | coiled-coil domain containing 9 |
CD151 | CD151 molecule (Raph blood group) |
CIC | capicua transcriptional repressor |
COMMD10 | COMM domain containing 10 |
CTSG | cathepsin G |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
DPP3 | dipeptidyl-peptidase 3 |
DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
E2F6 | E2F transcription factor 6 |
FAM136A | family with sequence similarity 136, member A |
FAM216A | family with sequence similarity 216, member A |
FAM222B | family with sequence similarity 222, member B |
FGR | FGR proto-oncogene, Src family tyrosine kinase |
GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
GMIP | GEM interacting protein |
GRAMD4 | GRAM domain containing 4 |
GTPBP3 | GTP binding protein 3 (mitochondrial) |
GTPBP6 | GTP binding protein 6 (putative) |
HINFP | histone H4 transcription factor |
HMHA1 | histocompatibility (minor) HA-1 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IFRD2 | interferon-related developmental regulator 2 |
IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
KCTD15 | potassium channel tetramerization domain containing 15 |
KLHL21 | kelch-like family member 21 |
LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) |
LMNB1 | lamin B1 |
LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor |
LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
MAT2A | methionine adenosyltransferase II, alpha |
MATK | megakaryocyte-associated tyrosine kinase |
MEPCE | methylphosphate capping enzyme |
MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) |
MON1B | MON1 secretory trafficking family member B |
MRPL12 | mitochondrial ribosomal protein L12 |
MRPS34 | mitochondrial ribosomal protein S34 |
MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
MX1 | MX dynamin-like GTPase 1 |
MYO9A | myosin IXA |
NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 |
P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
PEF1 | penta-EF-hand domain containing 1 |
PES1 | pescadillo ribosomal biogenesis factor 1 |
PFAS | phosphoribosylformylglycinamidine synthase |
PHF21A | PHD finger protein 21A |
PRMT3 | protein arginine methyltransferase 3 |
PRTN3 | proteinase 3 |
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
PUS1 | pseudouridylate synthase 1 |
PUS7 | pseudouridylate synthase 7 (putative) |
PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
SARS2 | seryl-tRNA synthetase 2, mitochondrial |
SCO2 | SCO2 cytochrome c oxidase assembly protein |
SDCCAG3 | serologically defined colon cancer antigen 3 |
SEH1L | SEH1-like (S. cerevisiae) |
SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
SNHG3 | small nucleolar RNA host gene 3 |
SNUPN | snurportin 1 |
SPI1 | Spi-1 proto-oncogene |
SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
STAG1 | stromal antigen 1 |
STEAP3 | STEAP family member 3, metalloreductase |
TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
TFB2M | transcription factor B2, mitochondrial |
THOC6 | THO complex 6 |
TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
TIPIN | TIMELESS interacting protein |
TMEM11 | transmembrane protein 11 |
TSPAN14 | tetraspanin 14 |
TTC27 | tetratricopeptide repeat domain 27 |
TTK | TTK protein kinase |
UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) |
UCK2 | uridine-cytidine kinase 2 |
UNG | uracil-DNA glycosylase |
XPOT | exportin, tRNA |
ZCCHC8 | zinc finger, CCHC domain containing 8 |
ZEB2 | zinc finger E-box binding homeobox 2 |
ZNF16 | zinc finger protein 16 |
ZNF692 | zinc finger protein 692 |
ZNF804A | zinc finger protein 804A |