trichostatin A-1785 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the trichostatin A-1785 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACOT7 acyl-CoA thioesterase 7
ACSL4 acyl-CoA synthetase long-chain family member 4
ADCY2 adenylate cyclase 2 (brain)
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AKAP13 A kinase (PRKA) anchor protein 13
ANKRD46 ankyrin repeat domain 46
ASPH aspartate beta-hydroxylase
ATG2A autophagy related 2A
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALU calumenin
CD70 CD70 molecule
CLCN7 chloride channel, voltage-sensitive 7
CPM carboxypeptidase M
CTRL chymotrypsin-like
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DFNA5 deafness, autosomal dominant 5
DOCK4 dedicator of cytokinesis 4
DTX4 deltex 4, E3 ubiquitin ligase
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
ECI2 enoyl-CoA delta isomerase 2
F11R F11 receptor
FAM63A family with sequence similarity 63, member A
FUCA1 fucosidase, alpha-L- 1, tissue
FZD2 frizzled class receptor 2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GATA2 GATA binding protein 2
GBAP1 glucosidase, beta, acid pseudogene 1
GLS glutaminase
GNS glucosamine (N-acetyl)-6-sulfatase
GPR107 G protein-coupled receptor 107
GPR65 G protein-coupled receptor 65
GPSM2 G-protein signaling modulator 2
HBB hemoglobin, beta
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H3E histone cluster 1, H3e
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HMGN5 high mobility group nucleosome binding domain 5
HOOK2 hook microtubule-tethering protein 2
HOXD1 homeobox D1
HRH1 histamine receptor H1
KIAA1467 KIAA1467
KIF5C kinesin family member 5C
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KRT2 keratin 2, type II
LHFP lipoma HMGIC fusion partner
LOC100131510 uncharacterized LOC100131510
MAGED2 melanoma antigen family D2
MARCKS myristoylated alanine-rich protein kinase C substrate
MBNL2 muscleblind-like splicing regulator 2
MEF2C myocyte enhancer factor 2C
MIPEP mitochondrial intermediate peptidase
MPV17 MpV17 mitochondrial inner membrane protein
MPZL1 myelin protein zero-like 1
MYH10 myosin, heavy chain 10, non-muscle
MYH14 myosin, heavy chain 14, non-muscle
MYO19 myosin XIX
NCAM1 neural cell adhesion molecule 1
NTNG1 netrin G1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OSBPL3 oxysterol binding protein-like 3
PCNXL2 pecanex-like 2 (Drosophila)
PFKM phosphofructokinase, muscle
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PSG9 pregnancy specific beta-1-glycoprotein 9
RAB33B RAB33B, member RAS oncogene family
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RFK riboflavin kinase
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
SAPCD1 suppressor APC domain containing 1
SATB1 SATB homeobox 1
SCAMP1 secretory carrier membrane protein 1
SCD5 stearoyl-CoA desaturase 5
SDC2 syndecan 2
SH2D1A SH2 domain containing 1A
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SNAP23 synaptosomal-associated protein, 23kDa
SP1 Sp1 transcription factor
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TFEC transcription factor EC
TPD52L1 tumor protein D52-like 1
TRIM9 tripartite motif containing 9
TSC22D3 TSC22 domain family, member 3
TUBA4B tubulin, alpha 4b
TUFT1 tuftelin 1
YLPM1 YLP motif containing 1
ZNF136 zinc finger protein 136
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRE5 adhesion G protein-coupled receptor E5
ADI1 acireductone dioxygenase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD11 ankyrin repeat domain 11
APOBR apolipoprotein B receptor
AVEN apoptosis, caspase activation inhibitor
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL7B B-cell CLL/lymphoma 7B
BMI1 BMI1 proto-oncogene, polycomb ring finger
C16ORF62 chromosome 16 open reading frame 62
C19ORF24 chromosome 19 open reading frame 24
C21ORF91 chromosome 21 open reading frame 91
C3AR1 complement component 3a receptor 1
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CD33 CD33 molecule
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLASRP CLK4-associating serine/arginine rich protein
CRIP1 cysteine-rich protein 1 (intestinal)
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAAF2 dynein, axonemal, assembly factor 2
DPP3 dipeptidyl-peptidase 3
ENDOG endonuclease G
FANCF Fanconi anemia, complementation group F
FURIN furin (paired basic amino acid cleaving enzyme)
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
KEAP1 kelch-like ECH-associated protein 1
KIZ kizuna centrosomal protein
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGOHB mago-nashi homolog B (Drosophila)
MCM10 minichromosome maintenance complex component 10
MED17 mediator complex subunit 17
MON1B MON1 secretory trafficking family member B
MRPL28 mitochondrial ribosomal protein L28
MRPS34 mitochondrial ribosomal protein S34
NCSTN nicastrin
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRBP1 nuclear receptor binding protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
ORC1 origin recognition complex, subunit 1
PANK4 pantothenate kinase 4
PCDHGB5 protocadherin gamma subfamily B, 5
PCNT pericentrin
PES1 pescadillo ribosomal biogenesis factor 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPAN peter pan homolog (Drosophila)
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTER phosphotriesterase related
PTGES2 prostaglandin E synthase 2
PUS1 pseudouridylate synthase 1
PUS7 pseudouridylate synthase 7 (putative)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB4B RAB4B, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCL1 RNA terminal phosphate cyclase-like 1
RIC8A RIC8 guanine nucleotide exchange factor A
SCO2 SCO2 cytochrome c oxidase assembly protein
SDC4 syndecan 4
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SSNA1 Sjogren syndrome nuclear autoantigen 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMEM39B transmembrane protein 39B
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TOE1 target of EGR1, member 1 (nuclear)
TRAPPC12 trafficking protein particle complex 12
TRIB3 tribbles pseudokinase 3
TRIM25 tripartite motif containing 25
TTC27 tetratricopeptide repeat domain 27
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VCPKMT valosin containing protein lysine (K) methyltransferase
VRK2 vaccinia related kinase 2
WDR13 WD repeat domain 13
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZNF197 zinc finger protein 197