Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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200 genes differentially expressed following the trichostatin A-1793 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD6 | abhydrolase domain containing 6 |
ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
ACSL3 | acyl-CoA synthetase long-chain family member 3 |
ADRB2 | adrenoceptor beta 2, surface |
ANGPTL4 | angiopoietin-like 4 |
AQP3 | aquaporin 3 (Gill blood group) |
ARG2 | arginase 2 |
ARHGAP26 | Rho GTPase activating protein 26 |
ARID5B | AT rich interactive domain 5B (MRF1-like) |
ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
ASMTL | acetylserotonin O-methyltransferase-like |
ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
AVPI1 | arginine vasopressin-induced 1 |
BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
BAIAP2 | BAI1-associated protein 2 |
BAMBI | BMP and activin membrane-bound inhibitor |
BCL6 | B-cell CLL/lymphoma 6 |
CCNA1 | cyclin A1 |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CFAP69 | cilia and flagella associated protein 69 |
CORO1A | coronin, actin binding protein, 1A |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CTGF | connective tissue growth factor |
CTH | cystathionine gamma-lyase |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
DOPEY1 | dopey family member 1 |
DUSP1 | dual specificity phosphatase 1 |
DUSP10 | dual specificity phosphatase 10 |
DUSP5 | dual specificity phosphatase 5 |
DUSP6 | dual specificity phosphatase 6 |
EFNB2 | ephrin-B2 |
EGR2 | early growth response 2 |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
ELOVL4 | ELOVL fatty acid elongase 4 |
EMP1 | epithelial membrane protein 1 |
F11R | F11 receptor |
FABP4 | fatty acid binding protein 4, adipocyte |
FLRT3 | fibronectin leucine rich transmembrane protein 3 |
FSCN1 | fascin actin-bundling protein 1 |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GLRX | glutaredoxin (thioltransferase) |
GMCL1 | germ cell-less, spermatogenesis associated 1 |
GMPR | guanosine monophosphate reductase |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
GTF2B | general transcription factor IIB |
H1F0 | H1 histone family, member 0 |
H1FX | H1 histone family, member X |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IL1RAP | interleukin 1 receptor accessory protein |
INSIG1 | insulin induced gene 1 |
IRF6 | interferon regulatory factor 6 |
IRS2 | insulin receptor substrate 2 |
KIF5C | kinesin family member 5C |
LINC00341 | long intergenic non-protein coding RNA 341 |
LMCD1 | LIM and cysteine-rich domains 1 |
LPIN1 | lipin 1 |
MAP2K3 | mitogen-activated protein kinase kinase 3 |
MAT2A | methionine adenosyltransferase II, alpha |
MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
MMP1 | matrix metallopeptidase 1 |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
NFIL3 | nuclear factor, interleukin 3 regulated |
PCDH9 | protocadherin 9 |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PRKCD | protein kinase C, delta |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
RAI2 | retinoic acid induced 2 |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RGS4 | regulator of G-protein signaling 4 |
RHOB | ras homolog family member B |
RNF24 | ring finger protein 24 |
SH3GL3 | SH3-domain GRB2-like 3 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
SQLE | squalene epoxidase |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STARD5 | StAR-related lipid transfer (START) domain containing 5 |
STAT1 | signal transducer and activator of transcription 1, 91kDa |
STC1 | stanniocalcin 1 |
STK17B | serine/threonine kinase 17b |
STOM | stomatin |
SYT1 | synaptotagmin I |
SYTL2 | synaptotagmin-like 2 |
TAOK3 | TAO kinase 3 |
TNIK | TRAF2 and NCK interacting kinase |
TUBB2B | tubulin, beta 2B class IIb |
TUFT1 | tuftelin 1 |
ZCCHC24 | zinc finger, CCHC domain containing 24 |
Symbol | Name |
---|---|
ADCY7 | adenylate cyclase 7 |
ADNP | activity-dependent neuroprotector homeobox |
AKAP8 | A kinase (PRKA) anchor protein 8 |
AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
BCAR3 | breast cancer anti-estrogen resistance 3 |
BRIX1 | BRX1, biogenesis of ribosomes |
CASD1 | CAS1 domain containing 1 |
CBR3 | carbonyl reductase 3 |
CLCF1 | cardiotrophin-like cytokine factor 1 |
COA7 | cytochrome c oxidase assembly factor 7 (putative) |
CTCF | CCCTC-binding factor (zinc finger protein) |
CUL1 | cullin 1 |
DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
DEPDC1 | DEP domain containing 1 |
EXOSC10 | exosome component 10 |
FADD | Fas (TNFRSF6)-associated via death domain |
FAIM | Fas apoptotic inhibitory molecule |
FOSL1 | FOS-like antigen 1 |
FOXA1 | forkhead box A1 |
FST | follistatin |
GBX2 | gastrulation brain homeobox 2 |
GLMN | glomulin, FKBP associated protein |
GTF2IRD1 | GTF2I repeat domain containing 1 |
H2AFY2 | H2A histone family, member Y2 |
HAS2 | hyaluronan synthase 2 |
HIRIP3 | HIRA interacting protein 3 |
HMGA2 | high mobility group AT-hook 2 |
INHBB | inhibin, beta B |
IRF9 | interferon regulatory factor 9 |
JADE1 | jade family PHD finger 1 |
KAT5 | K(lysine) acetyltransferase 5 |
KEAP1 | kelch-like ECH-associated protein 1 |
LIF | leukemia inhibitory factor |
LMNB1 | lamin B1 |
LPAR1 | lysophosphatidic acid receptor 1 |
LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
LUC7L2 | LUC7-like 2 (S. cerevisiae) |
MEPCE | methylphosphate capping enzyme |
METTL8 | methyltransferase like 8 |
MISP | mitotic spindle positioning |
MSL2 | male-specific lethal 2 homolog (Drosophila) |
MTPAP | mitochondrial poly(A) polymerase |
MX1 | MX dynamin-like GTPase 1 |
NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
NSD1 | nuclear receptor binding SET domain protein 1 |
NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
NUP62 | nucleoporin 62kDa |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
PHF11 | PHD finger protein 11 |
PMM2 | phosphomannomutase 2 |
PPAN | peter pan homolog (Drosophila) |
PPCS | phosphopantothenoylcysteine synthetase |
PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
PXDC1 | PX domain containing 1 |
PYCARD | PYD and CARD domain containing |
RBL1 | retinoblastoma-like 1 |
RBM4B | RNA binding motif protein 4B |
RIN2 | Ras and Rab interactor 2 |
RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
SCAF8 | SR-related CTD-associated factor 8 |
SCO2 | SCO2 cytochrome c oxidase assembly protein |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SETD1B | SET domain containing 1B |
SETMAR | SET domain and mariner transposase fusion gene |
SFMBT1 | Scm-like with four mbt domains 1 |
SIM2 | single-minded family bHLH transcription factor 2 |
SLC4A1AP | solute carrier family 4 (anion exchanger), member 1, adaptor protein |
SMAGP | small cell adhesion glycoprotein |
SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
SMYD5 | SMYD family member 5 |
SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
SPHK1 | sphingosine kinase 1 |
SRSF4 | serine/arginine-rich splicing factor 4 |
STBD1 | starch binding domain 1 |
STRN4 | striatin, calmodulin binding protein 4 |
STXBP3 | syntaxin binding protein 3 |
SUV420H1 | suppressor of variegation 4-20 homolog 1 (Drosophila) |
TACO1 | translational activator of mitochondrially encoded cytochrome c oxidase I |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
TOR3A | torsin family 3, member A |
TRIB3 | tribbles pseudokinase 3 |
TTC31 | tetratricopeptide repeat domain 31 |
VEGFC | vascular endothelial growth factor C |
VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
WBSCR16 | Williams-Beuren syndrome chromosome region 16 |
WDR6 | WD repeat domain 6 |
YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
ZC3H4 | zinc finger CCCH-type containing 4 |
ZC3H7A | zinc finger CCCH-type containing 7A |
ZCCHC10 | zinc finger, CCHC domain containing 10 |
ZNF165 | zinc finger protein 165 |
ZNF532 | zinc finger protein 532 |
ZNF562 | zinc finger protein 562 |
ZNF787 | zinc finger protein 787 |
ZSCAN31 | zinc finger and SCAN domain containing 31 |
ZZZ3 | zinc finger, ZZ-type containing 3 |