| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the trichostatin A-1891 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL3 | acyl-CoA synthetase long-chain family member 3 |
| ADRB2 | adrenoceptor beta 2, surface |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AHR | aryl hydrocarbon receptor |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARG2 | arginase 2 |
| ARL4D | ADP-ribosylation factor-like 4D |
| BAIAP2 | BAI1-associated protein 2 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BCL6 | B-cell CLL/lymphoma 6 |
| BLVRA | biliverdin reductase A |
| C18ORF8 | chromosome 18 open reading frame 8 |
| C2CD2L | C2CD2-like |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP68 | centrosomal protein 68kDa |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CRY1 | cryptochrome circadian clock 1 |
| CSNK1E | casein kinase 1, epsilon |
| CTGF | connective tissue growth factor |
| CTH | cystathionine gamma-lyase |
| CXADR | coxsackie virus and adenovirus receptor |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DENND3 | DENN/MADD domain containing 3 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP5 | dual specificity phosphatase 5 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNB2 | ephrin-B2 |
| EGR2 | early growth response 2 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EMP1 | epithelial membrane protein 1 |
| EVI5 | ecotropic viral integration site 5 |
| F2R | coagulation factor II (thrombin) receptor |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM134B | family with sequence similarity 134, member B |
| FAM188A | family with sequence similarity 188, member A |
| FBXO3 | F-box protein 3 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GLRX | glutaredoxin (thioltransferase) |
| GTF2B | general transcription factor IIB |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| H1F0 | H1 histone family, member 0 |
| H1FX | H1 histone family, member X |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIST1H2AG | histone cluster 1, H2ag |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSPA1A | heat shock 70kDa protein 1A |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IL11 | interleukin 11 |
| INSIG1 | insulin induced gene 1 |
| IRF6 | interferon regulatory factor 6 |
| IRS2 | insulin receptor substrate 2 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIF5C | kinesin family member 5C |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LPIN1 | lipin 1 |
| LYST | lysosomal trafficking regulator |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MICA | MHC class I polypeptide-related sequence A |
| MLF1 | myeloid leukemia factor 1 |
| MMP1 | matrix metallopeptidase 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NTF3 | neurotrophin 3 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RHOB | ras homolog family member B |
| RNF24 | ring finger protein 24 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SNX1 | sorting nexin 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SQLE | squalene epoxidase |
| STC1 | stanniocalcin 1 |
| TAGLN3 | transgelin 3 |
| TAOK3 | TAO kinase 3 |
| TBPL1 | TBP-like 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB2B | tubulin, beta 2B class IIb |
| TUFT1 | tuftelin 1 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF277 | zinc finger protein 277 |
| Symbol | Name |
|---|---|
| ABT1 | activator of basal transcription 1 |
| ADNP | activity-dependent neuroprotector homeobox |
| ADORA2B | adenosine A2b receptor |
| AKAP8 | A kinase (PRKA) anchor protein 8 |
| ATF1 | activating transcription factor 1 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BCL7A | B-cell CLL/lymphoma 7A |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| CBR3 | carbonyl reductase 3 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLK2 | CDC-like kinase 2 |
| COIL | coilin |
| CTCF | CCCTC-binding factor (zinc finger protein) |
| CUL1 | cullin 1 |
| EXOSC10 | exosome component 10 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM60A | family with sequence similarity 60, member A |
| FJX1 | four jointed box 1 (Drosophila) |
| FOSL1 | FOS-like antigen 1 |
| FOXA1 | forkhead box A1 |
| FST | follistatin |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| H2AFY2 | H2A histone family, member Y2 |
| HAS2 | hyaluronan synthase 2 |
| HMGA2 | high mobility group AT-hook 2 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F |
| IL6 | interleukin 6 |
| IL7R | interleukin 7 receptor |
| INHBB | inhibin, beta B |
| KEAP1 | kelch-like ECH-associated protein 1 |
| LIF | leukemia inhibitory factor |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LMNB1 | lamin B1 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MEPCE | methylphosphate capping enzyme |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MOCOS | molybdenum cofactor sulfurase |
| MTIF2 | mitochondrial translational initiation factor 2 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NCOA6 | nuclear receptor coactivator 6 |
| NLRX1 | NLR family member X1 |
| NMI | N-myc (and STAT) interactor |
| NUAK1 | NUAK family, SNF1-like kinase, 1 |
| NUP62 | nucleoporin 62kDa |
| PEF1 | penta-EF-hand domain containing 1 |
| PEX12 | peroxisomal biogenesis factor 12 |
| PLAU | plasminogen activator, urokinase |
| PMM2 | phosphomannomutase 2 |
| POGK | pogo transposable element with KRAB domain |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) |
| PPAN | peter pan homolog (Drosophila) |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RBM10 | RNA binding motif protein 10 |
| RBM23 | RNA binding motif protein 23 |
| RBM39 | RNA binding motif protein 39 |
| RIN2 | Ras and Rab interactor 2 |
| RNF220 | ring finger protein 220 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SCAF8 | SR-related CTD-associated factor 8 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SCRN1 | secernin 1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SMAGP | small cell adhesion glycoprotein |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) |
| SNUPN | snurportin 1 |
| SPOP | speckle-type POZ protein |
| SRSF4 | serine/arginine-rich splicing factor 4 |
| STXBP3 | syntaxin binding protein 3 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TACO1 | translational activator of mitochondrially encoded cytochrome c oxidase I |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TMEM168 | transmembrane protein 168 |
| TMEM185B | transmembrane protein 185B |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM68 | tripartite motif containing 68 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTC4 | tetratricopeptide repeat domain 4 |
| UNC50 | unc-50 homolog (C. elegans) |
| USP21 | ubiquitin specific peptidase 21 |
| VEGFC | vascular endothelial growth factor C |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WBSCR16 | Williams-Beuren syndrome chromosome region 16 |
| WDR6 | WD repeat domain 6 |
| WDR74 | WD repeat domain 74 |
| XBP1 | X-box binding protein 1 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZC3H7A | zinc finger CCCH-type containing 7A |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZNF175 | zinc finger protein 175 |
| ZNF532 | zinc finger protein 532 |
