Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the trichostatin A-2035 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABI2 | abl-interactor 2 |
ACP6 | acid phosphatase 6, lysophosphatidic |
ADAM8 | ADAM metallopeptidase domain 8 |
AHCYL2 | adenosylhomocysteinase-like 2 |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
ANXA6 | annexin A6 |
APAF1 | apoptotic peptidase activating factor 1 |
ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
ARID4A | AT rich interactive domain 4A (RBP1-like) |
ARID5B | AT rich interactive domain 5B (MRF1-like) |
ARNT | aryl hydrocarbon receptor nuclear translocator |
ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
ASMTL | acetylserotonin O-methyltransferase-like |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
BIN1 | bridging integrator 1 |
BMP15 | bone morphogenetic protein 15 |
CAPRIN2 | caprin family member 2 |
CASP2 | caspase 2, apoptosis-related cysteine peptidase |
CASP8 | caspase 8, apoptosis-related cysteine peptidase |
CAST | calpastatin |
CC2D1A | coiled-coil and C2 domain containing 1A |
CD59 | CD59 molecule, complement regulatory protein |
CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
CEP131 | centrosomal protein 131kDa |
CLDN11 | claudin 11 |
CLEC2B | C-type lectin domain family 2, member B |
CPM | carboxypeptidase M |
CREB3 | cAMP responsive element binding protein 3 |
CRMP1 | collapsin response mediator protein 1 |
CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
DHDDS | dehydrodolichyl diphosphate synthase |
DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
DNASE1L1 | deoxyribonuclease I-like 1 |
DOCK4 | dedicator of cytokinesis 4 |
DST | dystonin |
DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
ECI2 | enoyl-CoA delta isomerase 2 |
EPAS1 | endothelial PAS domain protein 1 |
F11R | F11 receptor |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
FIG4 | FIG4 phosphoinositide 5-phosphatase |
GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
ITM2C | integral membrane protein 2C |
KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 |
KHK | ketohexokinase (fructokinase) |
KIF5C | kinesin family member 5C |
KRT32 | keratin 32, type I |
LBP | lipopolysaccharide binding protein |
LHFP | lipoma HMGIC fusion partner |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
MPZL1 | myelin protein zero-like 1 |
NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
PCNXL2 | pecanex-like 2 (Drosophila) |
PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
PFN2 | profilin 2 |
PLS1 | plastin 1 |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
RAP1GAP | RAP1 GTPase activating protein |
RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
RECQL4 | RecQ protein-like 4 |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RHOC | ras homolog family member C |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SFTPB | surfactant protein B |
SHARPIN | SHANK-associated RH domain interactor |
SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STXBP1 | syntaxin binding protein 1 |
SUGP1 | SURP and G patch domain containing 1 |
SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
SUPT4H1 | suppressor of Ty 4 homolog 1 (S. cerevisiae) |
TBC1D22A | TBC1 domain family, member 22A |
TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
TES | testin LIM domain protein |
TPD52L1 | tumor protein D52-like 1 |
TRIM62 | tripartite motif containing 62 |
TSPAN13 | tetraspanin 13 |
TTC26 | tetratricopeptide repeat domain 26 |
TUFT1 | tuftelin 1 |
WDR19 | WD repeat domain 19 |
WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
ZNF45 | zinc finger protein 45 |
ZSWIM8 | zinc finger, SWIM-type containing 8 |
Symbol | Name |
---|---|
ADCY7 | adenylate cyclase 7 |
ADI1 | acireductone dioxygenase 1 |
ALDOC | aldolase C, fructose-bisphosphate |
ARAF | A-Raf proto-oncogene, serine/threonine kinase |
AVEN | apoptosis, caspase activation inhibitor |
BCL10 | B-cell CLL/lymphoma 10 |
CARD9 | caspase recruitment domain family, member 9 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCL2 | chemokine (C-C motif) ligand 2 |
CD14 | CD14 molecule |
CDC73 | cell division cycle 73 |
CERS2 | ceramide synthase 2 |
CHMP3 | charged multivesicular body protein 3 |
CISH | cytokine inducible SH2-containing protein |
CTCF | CCCTC-binding factor (zinc finger protein) |
CTPS1 | CTP synthase 1 |
DENND4B | DENN/MADD domain containing 4B |
DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
ERCC2 | excision repair cross-complementation group 2 |
EXOSC10 | exosome component 10 |
FAM136A | family with sequence similarity 136, member A |
FAM216A | family with sequence similarity 216, member A |
FBXW4 | F-box and WD repeat domain containing 4 |
FES | FES proto-oncogene, tyrosine kinase |
FGR | FGR proto-oncogene, Src family tyrosine kinase |
FMNL1 | formin-like 1 |
GBAS | glioblastoma amplified sequence |
GMEB1 | glucocorticoid modulatory element binding protein 1 |
GMIP | GEM interacting protein |
GMPPB | GDP-mannose pyrophosphorylase B |
GPR183 | G protein-coupled receptor 183 |
GRWD1 | glutamate-rich WD repeat containing 1 |
GTPBP6 | GTP binding protein 6 (putative) |
HDAC4 | histone deacetylase 4 |
IFRD2 | interferon-related developmental regulator 2 |
ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
KIF20B | kinesin family member 20B |
KLHL21 | kelch-like family member 21 |
KPTN | kaptin (actin binding protein) |
LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) |
LINC00341 | long intergenic non-protein coding RNA 341 |
METTL21B | methyltransferase like 21B |
MGMT | O-6-methylguanine-DNA methyltransferase |
MORC3 | MORC family CW-type zinc finger 3 |
MPDU1 | mannose-P-dolichol utilization defect 1 |
MRPS34 | mitochondrial ribosomal protein S34 |
MTERF3 | mitochondrial transcription termination factor 3 |
MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
MYBBP1A | MYB binding protein (P160) 1a |
NEFH | neurofilament, heavy polypeptide |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
NGRN | neugrin, neurite outgrowth associated |
NIP7 | NIP7, nucleolar pre-rRNA processing protein |
NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor |
NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 |
NUP43 | nucleoporin 43kDa |
PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
PCNT | pericentrin |
PCSK7 | proprotein convertase subtilisin/kexin type 7 |
PNRC1 | proline-rich nuclear receptor coactivator 1 |
POGLUT1 | protein O-glucosyltransferase 1 |
POTEKP | POTE ankyrin domain family, member K, pseudogene |
PRMT3 | protein arginine methyltransferase 3 |
PRTN3 | proteinase 3 |
PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
PUS7 | pseudouridylate synthase 7 (putative) |
RNH1 | ribonuclease/angiogenin inhibitor 1 |
RPE | ribulose-5-phosphate-3-epimerase |
RPIA | ribose 5-phosphate isomerase A |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
RPS14P3 | ribosomal protein S14 pseudogene 3 |
RSF1 | remodeling and spacing factor 1 |
SACS | sacsin molecular chaperone |
SDF4 | stromal cell derived factor 4 |
SEH1L | SEH1-like (S. cerevisiae) |
SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 |
SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
SLC25A38 | solute carrier family 25, member 38 |
SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
SMNDC1 | survival motor neuron domain containing 1 |
SNHG3 | small nucleolar RNA host gene 3 |
SNUPN | snurportin 1 |
SPIN1 | spindlin 1 |
TIPIN | TIMELESS interacting protein |
TRAPPC12 | trafficking protein particle complex 12 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
TSSC4 | tumor suppressing subtransferable candidate 4 |
UCK2 | uridine-cytidine kinase 2 |
UNKL | unkempt family zinc finger-like |
WBSCR16 | Williams-Beuren syndrome chromosome region 16 |
XPOT | exportin, tRNA |
YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
ZCCHC10 | zinc finger, CCHC domain containing 10 |