trichostatin A-2208 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the trichostatin A-2208 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADGRL2 adhesion G protein-coupled receptor L2
AMIGO2 adhesion molecule with Ig-like domain 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARG2 arginase 2
ARMC9 armadillo repeat containing 9
ATP13A2 ATPase type 13A2
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BIK BCL2-interacting killer (apoptosis-inducing)
C17ORF59 chromosome 17 open reading frame 59
C21ORF2 chromosome 21 open reading frame 2
CD59 CD59 molecule, complement regulatory protein
CDR2L cerebellar degeneration-related protein 2-like
CKB creatine kinase, brain
CNTN5 contactin 5
CREB3L1 cAMP responsive element binding protein 3-like 1
CTSV cathepsin V
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DKFZP434C153 DKFZP434C153 protein
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOCK4 dedicator of cytokinesis 4
DOCK6 dedicator of cytokinesis 6
DSC3 desmocollin 3
DSE dermatan sulfate epimerase
DSP desmoplakin
ECI2 enoyl-CoA delta isomerase 2
EFNB2 ephrin-B2
EPAS1 endothelial PAS domain protein 1
ETV1 ets variant 1
F11R F11 receptor
FAS Fas cell surface death receptor
FBP1 fructose-1,6-bisphosphatase 1
FGF9 fibroblast growth factor 9
FZD4 frizzled class receptor 4
GIPC1 GIPC PDZ domain containing family, member 1
HNF1B HNF1 homeobox B
HSF2BP heat shock transcription factor 2 binding protein
HSPA2 heat shock 70kDa protein 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IMPG2 interphotoreceptor matrix proteoglycan 2
INHBA inhibin, beta A
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF5A kinesin family member 5A
KIF5C kinesin family member 5C
KLC2 kinesin light chain 2
LAD1 ladinin 1
LOC730101 uncharacterized LOC730101
MAL mal, T-cell differentiation protein
MARCKS myristoylated alanine-rich protein kinase C substrate
METTL7A methyltransferase like 7A
MLF1 myeloid leukemia factor 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MPZL1 myelin protein zero-like 1
MTUS1 microtubule associated tumor suppressor 1
MVP major vault protein
MYO1B myosin IB
NCAM1 neural cell adhesion molecule 1
NOTCH4 notch 4
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NRP1 neuropilin 1
OLFML2A olfactomedin-like 2A
PALLD palladin, cytoskeletal associated protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAX5 paired box 5
PCNXL2 pecanex-like 2 (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRL platelet-derived growth factor receptor-like
PFN2 profilin 2
PLCL1 phospholipase C-like 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
PLSCR3 phospholipid scramblase 3
PMP22 peripheral myelin protein 22
POU4F1 POU class 4 homeobox 1
RASAL2 RAS protein activator like 2
RIMS3 regulating synaptic membrane exocytosis 3
SLAMF7 SLAM family member 7
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT4 signal transducer and activator of transcription 4
STON1 stonin 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX15 testis expressed 15
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TNIK TRAF2 and NCK interacting kinase
TNNT1 troponin T type 1 (skeletal, slow)
TP53I11 tumor protein p53 inducible protein 11
TPD52L1 tumor protein D52-like 1
TPM1 tropomyosin 1 (alpha)
TRIM9 tripartite motif containing 9
TSPAN13 tetraspanin 13
TTC38 tetratricopeptide repeat domain 38
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRE3 adhesion G protein-coupled receptor E3
ADI1 acireductone dioxygenase 1
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ARSB arylsulfatase B
ASAP1-IT1 ASAP1 intronic transcript 1
ASGR2 asialoglycoprotein receptor 2
AVEN apoptosis, caspase activation inhibitor
B9D2 B9 protein domain 2
BAHCC1 BAH domain and coiled-coil containing 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF68 chromosome 11 open reading frame 68
C14ORF93 chromosome 14 open reading frame 93
C17ORF70 chromosome 17 open reading frame 70
C22ORF29 chromosome 22 open reading frame 29
CCDC85C coiled-coil domain containing 85C
CCDC9 coiled-coil domain containing 9
CD320 CD320 molecule
CENPO centromere protein O
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CNTN1 contactin 1
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DCPS decapping enzyme, scavenger
DGKG diacylglycerol kinase, gamma 90kDa
DOC2A double C2-like domains, alpha
DOK3 docking protein 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPX eosinophil peroxidase
FRMD1 FERM domain containing 1
GTPBP6 GTP binding protein 6 (putative)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H4F histone cluster 1, H4f
HS1BP3 HCLS1 binding protein 3
IDI2-AS1 IDI2 antisense RNA 1
IFRD2 interferon-related developmental regulator 2
IL12RB1 interleukin 12 receptor, beta 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF8 interferon regulatory factor 8
JADE1 jade family PHD finger 1
JMJD4 jumonji domain containing 4
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KDM8 lysine (K)-specific demethylase 8
KPTN kaptin (actin binding protein)
LECT1 leukocyte cell derived chemotaxin 1
LIMS2 LIM and senescent cell antigen-like domains 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRK1 leucine-rich repeat kinase 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
METTL8 methyltransferase like 8
MMRN2 multimerin 2
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MUC3A mucin 3A, cell surface associated
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NT5M 5',3'-nucleotidase, mitochondrial
NTF3 neurotrophin 3
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
OMG oligodendrocyte myelin glycoprotein
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PROL1 proline rich, lacrimal 1
PTPRS protein tyrosine phosphatase, receptor type, S
RABL6 RAB, member RAS oncogene family-like 6
RCL1 RNA terminal phosphate cyclase-like 1
RGS19 regulator of G-protein signaling 19
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNASE3 ribonuclease, RNase A family, 3
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNH1 ribonuclease/angiogenin inhibitor 1
RSAD1 radical S-adenosyl methionine domain containing 1
RWDD3 RWD domain containing 3
SH2D4A SH2 domain containing 4A
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SP1 Sp1 transcription factor
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYNC syncoilin, intermediate filament protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBKBP1 TBK1 binding protein 1
TERT telomerase reverse transcriptase
TKFC triokinase/FMN cyclase
TMEM2 transmembrane protein 2
TMEM212 transmembrane protein 212
TPM3 tropomyosin 3
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TSPYL2 TSPY-like 2
TTC27 tetratricopeptide repeat domain 27
USP19 ubiquitin specific peptidase 19
USP36 ubiquitin specific peptidase 36
WBSCR16 Williams-Beuren syndrome chromosome region 16
ZBTB38 zinc finger and BTB domain containing 38
ZCWPW1 zinc finger, CW type with PWWP domain 1