Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the trichostatin A-2247 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
ADM | adrenomedullin |
AHNAK2 | AHNAK nucleoprotein 2 |
ANG | angiogenin, ribonuclease, RNase A family, 5 |
ANGPTL4 | angiopoietin-like 4 |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
BAIAP3 | BAI1-associated protein 3 |
BIRC3 | baculoviral IAP repeat containing 3 |
CA5B | carbonic anhydrase VB, mitochondrial |
CASC1 | cancer susceptibility candidate 1 |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CEP112 | centrosomal protein 112kDa |
CLGN | calmegin |
CORO1A | coronin, actin binding protein, 1A |
CXADR | coxsackie virus and adenovirus receptor |
CYLD | cylindromatosis (turban tumor syndrome) |
CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DLX2 | distal-less homeobox 2 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DOCK4 | dedicator of cytokinesis 4 |
DPF1 | D4, zinc and double PHD fingers family 1 |
DPYSL4 | dihydropyrimidinase-like 4 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
EFNB3 | ephrin-B3 |
ELOVL4 | ELOVL fatty acid elongase 4 |
FAM46C | family with sequence similarity 46, member C |
FKBP1B | FK506 binding protein 1B, 12.6 kDa |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GEM | GTP binding protein overexpressed in skeletal muscle |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
GLDC | glycine dehydrogenase (decarboxylating) |
GLRX | glutaredoxin (thioltransferase) |
GMPR | guanosine monophosphate reductase |
GRK5 | G protein-coupled receptor kinase 5 |
HBEGF | heparin-binding EGF-like growth factor |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HLA-DMB | major histocompatibility complex, class II, DM beta |
HOXA1 | homeobox A1 |
HPCAL4 | hippocalcin like 4 |
HYAL1 | hyaluronoglucosaminidase 1 |
IFI6 | interferon, alpha-inducible protein 6 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IL21R | interleukin 21 receptor |
ITM2C | integral membrane protein 2C |
KIAA0513 | KIAA0513 |
KIF21B | kinesin family member 21B |
KLHL24 | kelch-like family member 24 |
LINC00341 | long intergenic non-protein coding RNA 341 |
LYST | lysosomal trafficking regulator |
MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
MUC3B | mucin 3B, cell surface associated |
NAP1L3 | nucleosome assembly protein 1-like 3 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NPC1 | Niemann-Pick disease, type C1 |
NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
OASL | 2'-5'-oligoadenylate synthetase-like |
PADI3 | peptidyl arginine deiminase, type III |
PLCD1 | phospholipase C, delta 1 |
PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
PRPH | peripherin |
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
PTAFR | platelet-activating factor receptor |
PTRF | polymerase I and transcript release factor |
RAI2 | retinoic acid induced 2 |
RGCC | regulator of cell cycle |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RGS2 | regulator of G-protein signaling 2 |
RND1 | Rho family GTPase 1 |
RNFT1 | ring finger protein, transmembrane 1 |
RPL3L | ribosomal protein L3-like |
RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
RTN2 | reticulon 2 |
RUNDC3B | RUN domain containing 3B |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SH3GL3 | SH3-domain GRB2-like 3 |
SIRT4 | sirtuin 4 |
SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
SORBS1 | sorbin and SH3 domain containing 1 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STON1 | stonin 1 |
SYT11 | synaptotagmin XI |
TBXA2R | thromboxane A2 receptor |
TMEM45A | transmembrane protein 45A |
TUFT1 | tuftelin 1 |
TXNIP | thioredoxin interacting protein |
VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
ZBTB18 | zinc finger and BTB domain containing 18 |
ZCCHC24 | zinc finger, CCHC domain containing 24 |
ZDHHC11 | zinc finger, DHHC-type containing 11 |
ZNF10 | zinc finger protein 10 |
ZNF204P | zinc finger protein 204, pseudogene |
Symbol | Name |
---|---|
ACKR3 | atypical chemokine receptor 3 |
ADNP | activity-dependent neuroprotector homeobox |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
ATAD2B | ATPase family, AAA domain containing 2B |
BATF | basic leucine zipper transcription factor, ATF-like |
BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
C5AR2 | complement component 5a receptor 2 |
CALHM2 | calcium homeostasis modulator 2 |
CASD1 | CAS1 domain containing 1 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCDC94 | coiled-coil domain containing 94 |
CCND1 | cyclin D1 |
CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
CLCF1 | cardiotrophin-like cytokine factor 1 |
CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
COIL | coilin |
CTCF | CCCTC-binding factor (zinc finger protein) |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
CUL1 | cullin 1 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
EGR3 | early growth response 3 |
EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
FAM57A | family with sequence similarity 57, member A |
FJX1 | four jointed box 1 (Drosophila) |
FOSL1 | FOS-like antigen 1 |
FOXA1 | forkhead box A1 |
GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
GABPB1 | GA binding protein transcription factor, beta subunit 1 |
GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
GMEB1 | glucocorticoid modulatory element binding protein 1 |
HIRIP3 | HIRA interacting protein 3 |
HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
IL4R | interleukin 4 receptor |
INHBB | inhibin, beta B |
IRS1 | insulin receptor substrate 1 |
IRX5 | iroquois homeobox 5 |
ITPKB | inositol-trisphosphate 3-kinase B |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
KCTD15 | potassium channel tetramerization domain containing 15 |
KEAP1 | kelch-like ECH-associated protein 1 |
KIAA0125 | KIAA0125 |
KLF3 | Kruppel-like factor 3 (basic) |
LIG3 | ligase III, DNA, ATP-dependent |
LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
LUC7L2 | LUC7-like 2 (S. cerevisiae) |
LY6D | lymphocyte antigen 6 complex, locus D |
LY6G5C | lymphocyte antigen 6 complex, locus G5C |
MEPCE | methylphosphate capping enzyme |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
MSL1 | male-specific lethal 1 homolog (Drosophila) |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
MYD88 | myeloid differentiation primary response 88 |
NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
NLRX1 | NLR family member X1 |
NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
NRIP1 | nuclear receptor interacting protein 1 |
NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor |
NUAK1 | NUAK family, SNF1-like kinase, 1 |
OSGIN1 | oxidative stress induced growth inhibitor 1 |
P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
PCDHB3 | protocadherin beta 3 |
PDGFA | platelet-derived growth factor alpha polypeptide |
POGK | pogo transposable element with KRAB domain |
PPCS | phosphopantothenoylcysteine synthetase |
PRCC | papillary renal cell carcinoma (translocation-associated) |
PRR15L | proline rich 15-like |
RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
RNF220 | ring finger protein 220 |
RWDD3 | RWD domain containing 3 |
SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
SETD1B | SET domain containing 1B |
SH2D4A | SH2 domain containing 4A |
SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
SNHG3 | small nucleolar RNA host gene 3 |
SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
SRSF4 | serine/arginine-rich splicing factor 4 |
STC2 | stanniocalcin 2 |
TNS3 | tensin 3 |
TRIB3 | tribbles pseudokinase 3 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
TSKU | tsukushi, small leucine rich proteoglycan |
UBTF | upstream binding transcription factor, RNA polymerase I |
UBXN8 | UBX domain protein 8 |
USP21 | ubiquitin specific peptidase 21 |
VWA9 | von Willebrand factor A domain containing 9 |
XBP1 | X-box binding protein 1 |
ZBED1 | zinc finger, BED-type containing 1 |
ZFHX3 | zinc finger homeobox 3 |
ZHX2 | zinc fingers and homeoboxes 2 |
ZIC1 | Zic family member 1 |
ZMIZ1 | zinc finger, MIZ-type containing 1 |
ZNF692 | zinc finger protein 692 |
ZNHIT2 | zinc finger, HIT-type containing 2 |