trichostatin A-2474 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the trichostatin A-2474 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD2 adducin 2 (beta)
ADGRL2 adhesion G protein-coupled receptor L2
ANG angiogenin, ribonuclease, RNase A family, 5
ATP13A2 ATPase type 13A2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BEND5 BEN domain containing 5
BIN1 bridging integrator 1
BMP6 bone morphogenetic protein 6
C22ORF24 chromosome 22 open reading frame 24
CD59 CD59 molecule, complement regulatory protein
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHRM3 cholinergic receptor, muscarinic 3
CPM carboxypeptidase M
CREM cAMP responsive element modulator
CUL2 cullin 2
CXADR coxsackie virus and adenovirus receptor
DFNB31 deafness, autosomal recessive 31
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
ECI2 enoyl-CoA delta isomerase 2
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EPAS1 endothelial PAS domain protein 1
EPHB2 EPH receptor B2
EPX eosinophil peroxidase
FAM49A family with sequence similarity 49, member A
FER fer (fps/fes related) tyrosine kinase
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCH1 GTP cyclohydrolase 1
GLRX glutaredoxin (thioltransferase)
GPR65 G protein-coupled receptor 65
GRIK5 glutamate receptor, ionotropic, kainate 5
HEG1 heart development protein with EGF-like domains 1
HOXA4 homeobox A4
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNA16 interferon, alpha 16
IL15RA interleukin 15 receptor, alpha
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KIF5C kinesin family member 5C
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLF12 Kruppel-like factor 12
KLF3 Kruppel-like factor 3 (basic)
LHX2 LIM homeobox 2
LOC730101 uncharacterized LOC730101
LZTS3 leucine zipper, putative tumor suppressor family member 3
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK1 MAP/microtubule affinity-regulating kinase 1
MCAM melanoma cell adhesion molecule
MLF1 myeloid leukemia factor 1
MPZL1 myelin protein zero-like 1
MTUS1 microtubule associated tumor suppressor 1
MYH10 myosin, heavy chain 10, non-muscle
MYO1E myosin IE
NEUROD4 neuronal differentiation 4
NR4A3 nuclear receptor subfamily 4, group A, member 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCDH9 protocadherin 9
PCLO piccolo presynaptic cytomatrix protein
PCNXL2 pecanex-like 2 (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PEX3 peroxisomal biogenesis factor 3
PFN2 profilin 2
PGBD5 piggyBac transposable element derived 5
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
POU4F1 POU class 4 homeobox 1
RAB6B RAB6B, member RAS oncogene family
RANBP1 RAN binding protein 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
RPS4Y1 ribosomal protein S4, Y-linked 1
SAFB scaffold attachment factor B
SCML1 sex comb on midleg-like 1 (Drosophila)
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SPINT1 serine peptidase inhibitor, Kunitz type 1
SRPX sushi-repeat containing protein, X-linked
SSH3 slingshot protein phosphatase 3
STON1 stonin 1
THAP10 THAP domain containing 10
TMCC1 transmembrane and coiled-coil domain family 1
TPD52L1 tumor protein D52-like 1
TPM1 tropomyosin 1 (alpha)
TRIM62 tripartite motif containing 62
TSPAN13 tetraspanin 13
TTLL1 tubulin tyrosine ligase-like family member 1
TTLL7 tubulin tyrosine ligase-like family member 7
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
ULBP2 UL16 binding protein 2
VASP vasodilator-stimulated phosphoprotein

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADI1 acireductone dioxygenase 1
AEN apoptosis enhancing nuclease
ANKRD55 ankyrin repeat domain 55
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARRB1 arrestin, beta 1
ASGR2 asialoglycoprotein receptor 2
BRIX1 BRX1, biogenesis of ribosomes
C9ORF3 chromosome 9 open reading frame 3
CCDC186 coiled-coil domain containing 186
CCDC94 coiled-coil domain containing 94
CD300C CD300c molecule
CHML choroideremia-like (Rab escort protein 2)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOK2 docking protein 2, 56kDa
DOK5 docking protein 5
DSPP dentin sialophosphoprotein
DYSF dysferlin
ECSIT ECSIT signalling integrator
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EXD3 exonuclease 3'-5' domain containing 3
FAM172A family with sequence similarity 172, member A
FGGY FGGY carbohydrate kinase domain containing
FKBP5 FK506 binding protein 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GTF2I general transcription factor IIi
HOXA10 homeobox A10
HP haptoglobin
HRH2 histamine receptor H2
HSPA1L heat shock 70kDa protein 1-like
ICAM5 intercellular adhesion molecule 5, telencephalin
IFRD2 interferon-related developmental regulator 2
IL3RA interleukin 3 receptor, alpha (low affinity)
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INHBE inhibin, beta E
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA1024 KIAA1024
KLF1 Kruppel-like factor 1 (erythroid)
KPTN kaptin (actin binding protein)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
MAGEF1 melanoma antigen family F1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
METTL16 methyltransferase like 16
MICA MHC class I polypeptide-related sequence A
MIR22HG MIR22 host gene
MPDU1 mannose-P-dolichol utilization defect 1
NARFL nuclear prelamin A recognition factor-like
NRBP1 nuclear receptor binding protein 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PRR4 proline rich 4 (lacrimal)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RETN resistin
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
RNH1 ribonuclease/angiogenin inhibitor 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCGB2A2 secretoglobin, family 2A, member 2
SENP7 SUMO1/sentrin specific peptidase 7
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMYD5 SMYD family member 5
SNHG3 small nucleolar RNA host gene 3
SNX15 sorting nexin 15
SOX12 SRY (sex determining region Y)-box 12
SPI1 Spi-1 proto-oncogene
STAG1 stromal antigen 1
TEC tec protein tyrosine kinase
TERT telomerase reverse transcriptase
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THOC6 THO complex 6
TMEM53 transmembrane protein 53
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRABD TraB domain containing
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR62 WD repeat domain 62
ZNF428 zinc finger protein 428
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768
ZNF804A zinc finger protein 804A