trichostatin A-2721 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the trichostatin A-2721 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ALK anaplastic lymphoma receptor tyrosine kinase
AMPH amphiphysin
ANG angiogenin, ribonuclease, RNase A family, 5
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BEGAIN brain-enriched guanylate kinase-associated
BIK BCL2-interacting killer (apoptosis-inducing)
BIN1 bridging integrator 1
CCDC28B coiled-coil domain containing 28B
CD48 CD48 molecule
CD59 CD59 molecule, complement regulatory protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDO1 cysteine dioxygenase type 1
CEP70 centrosomal protein 70kDa
CHRM3 cholinergic receptor, muscarinic 3
COPZ2 coatomer protein complex, subunit zeta 2
CREB3L1 cAMP responsive element binding protein 3-like 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDAH2 dimethylarginine dimethylaminohydrolase 2
DHRS9 dehydrogenase/reductase (SDR family) member 9
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNMBP dynamin binding protein
DSP desmoplakin
ECI2 enoyl-CoA delta isomerase 2
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFNA5 ephrin-A5
EPAS1 endothelial PAS domain protein 1
ETV1 ets variant 1
EXPH5 exophilin 5
FAM13A family with sequence similarity 13, member A
FAS Fas cell surface death receptor
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXC1 forkhead box C1
FOXO1 forkhead box O1
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GCH1 GTP cyclohydrolase 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOXA1 homeobox A1
HPSE heparanase
HSPA2 heat shock 70kDa protein 2
IFI6 interferon, alpha-inducible protein 6
IFT27 intraflagellar transport 27
IL3RA interleukin 3 receptor, alpha (low affinity)
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGA7 integrin, alpha 7
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KIAA0226L KIAA0226-like
KIF5C kinesin family member 5C
KLC2 kinesin light chain 2
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LAMP1 lysosomal-associated membrane protein 1
LEF1 lymphoid enhancer-binding factor 1
LHX2 LIM homeobox 2
LOC730101 uncharacterized LOC730101
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAL mal, T-cell differentiation protein
MAMLD1 mastermind-like domain containing 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MPZL1 myelin protein zero-like 1
MYH14 myosin, heavy chain 14, non-muscle
MYO1E myosin IE
NCAM1 neural cell adhesion molecule 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NLRP1 NLR family, pyrin domain containing 1
NXN nucleoredoxin
PAX5 paired box 5
PFN2 profilin 2
PGBD5 piggyBac transposable element derived 5
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLS1 plastin 1
POU4F1 POU class 4 homeobox 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB6B RAB6B, member RAS oncogene family
RAD51B RAD51 paralog B
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGCE sarcoglycan, epsilon
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGLEC7 sialic acid binding Ig-like lectin 7
STAP1 signal transducing adaptor family member 1
STAT4 signal transducer and activator of transcription 4
STON1 stonin 1
SYNM synemin, intermediate filament protein
TAOK2 TAO kinase 2
TBC1D16 TBC1 domain family, member 16
THAP10 THAP domain containing 10
TNIK TRAF2 and NCK interacting kinase
TPMT thiopurine S-methyltransferase
TRIM62 tripartite motif containing 62
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
ZC2HC1A zinc finger, C2HC-type containing 1A

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ASGR2 asialoglycoprotein receptor 2
BAHCC1 BAH domain and coiled-coil containing 1
BMP15 bone morphogenetic protein 15
C17ORF53 chromosome 17 open reading frame 53
C5 complement component 5
CBX7 chromobox homolog 7
CCDC94 coiled-coil domain containing 94
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CORT cortistatin
CRYGC crystallin, gamma C
CTDNEP1 CTD nuclear envelope phosphatase 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DEAF1 DEAF1 transcription factor
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DSPP dentin sialophosphoprotein
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EPHB6 EPH receptor B6
FAM120C family with sequence similarity 120C
FKBP9 FK506 binding protein 9, 63 kDa
FLT4 fms-related tyrosine kinase 4
GMIP GEM interacting protein
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
GPR27 G protein-coupled receptor 27
GRIP2 glutamate receptor interacting protein 2
GSTT1 glutathione S-transferase theta 1
GSTZ1 glutathione S-transferase zeta 1
GTF2I general transcription factor IIi
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AE histone cluster 1, H2ae
HIST1H2AI histone cluster 1, H2ai
HIST1H3B histone cluster 1, H3b
IL2 interleukin 2
INF2 inverted formin, FH2 and WH2 domain containing
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1024 KIAA1024
KIF17 kinesin family member 17
LNPEP leucyl/cystinyl aminopeptidase
LOC257152 uncharacterized LOC257152
MAB21L1 mab-21-like 1 (C. elegans)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEP1B meprin A, beta
METTL21B methyltransferase like 21B
MLPH melanophilin
MOCS3 molybdenum cofactor synthesis 3
MTSS1L metastasis suppressor 1-like
NEUROD4 neuronal differentiation 4
NNAT neuronatin
NOD2 nucleotide-binding oligomerization domain containing 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDH12 protocadherin 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIPOX pipecolic acid oxidase
PKD2L2 polycystic kidney disease 2-like 2
PLA2G1B phospholipase A2, group IB (pancreas)
PLCB4 phospholipase C, beta 4
PMF1 polyamine-modulated factor 1
PRDM1 PR domain containing 1, with ZNF domain
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PYGB phosphorylase, glycogen; brain
REC8 REC8 meiotic recombination protein
RECQL4 RecQ protein-like 4
RHBDD3 rhomboid domain containing 3
RNF126P1 ring finger protein 126 pseudogene 1
RUSC2 RUN and SH3 domain containing 2
S1PR4 sphingosine-1-phosphate receptor 4
SCGB2A2 secretoglobin, family 2A, member 2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPATA1 spermatogenesis associated 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAS2R10 taste receptor, type 2, member 10
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEAD3 TEA domain family member 3
TET3 tet methylcytosine dioxygenase 3
TMC5 transmembrane channel-like 5
TMEM209 transmembrane protein 209
TPM3 tropomyosin 3
TPRA1 transmembrane protein, adipocyte asscociated 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC27 tetratricopeptide repeat domain 27
UNG uracil-DNA glycosylase
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR6 WD repeat domain 6
XAF1 XIAP associated factor 1
ZNF34 zinc finger protein 34
ZNF749 zinc finger protein 749