Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the trichostatin A-2721 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
ALK | anaplastic lymphoma receptor tyrosine kinase |
AMPH | amphiphysin |
ANG | angiogenin, ribonuclease, RNase A family, 5 |
ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
BEGAIN | brain-enriched guanylate kinase-associated |
BIK | BCL2-interacting killer (apoptosis-inducing) |
BIN1 | bridging integrator 1 |
CCDC28B | coiled-coil domain containing 28B |
CD48 | CD48 molecule |
CD59 | CD59 molecule, complement regulatory protein |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CDO1 | cysteine dioxygenase type 1 |
CEP70 | centrosomal protein 70kDa |
CHRM3 | cholinergic receptor, muscarinic 3 |
COPZ2 | coatomer protein complex, subunit zeta 2 |
CREB3L1 | cAMP responsive element binding protein 3-like 1 |
CTNNA2 | catenin (cadherin-associated protein), alpha 2 |
DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
DNMBP | dynamin binding protein |
DSP | desmoplakin |
ECI2 | enoyl-CoA delta isomerase 2 |
EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
EFNA5 | ephrin-A5 |
EPAS1 | endothelial PAS domain protein 1 |
ETV1 | ets variant 1 |
EXPH5 | exophilin 5 |
FAM13A | family with sequence similarity 13, member A |
FAS | Fas cell surface death receptor |
FKBP1B | FK506 binding protein 1B, 12.6 kDa |
FOXC1 | forkhead box C1 |
FOXO1 | forkhead box O1 |
GABARAPL1 | GABA(A) receptor-associated protein like 1 |
GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
GCH1 | GTP cyclohydrolase 1 |
HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
HOXA1 | homeobox A1 |
HPSE | heparanase |
HSPA2 | heat shock 70kDa protein 2 |
IFI6 | interferon, alpha-inducible protein 6 |
IFT27 | intraflagellar transport 27 |
IL3RA | interleukin 3 receptor, alpha (low affinity) |
INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
ITGA7 | integrin, alpha 7 |
ITIH4 | inter-alpha-trypsin inhibitor heavy chain family, member 4 |
KIAA0226L | KIAA0226-like |
KIF5C | kinesin family member 5C |
KLC2 | kinesin light chain 2 |
KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
LAMP1 | lysosomal-associated membrane protein 1 |
LEF1 | lymphoid enhancer-binding factor 1 |
LHX2 | LIM homeobox 2 |
LOC730101 | uncharacterized LOC730101 |
LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
MAL | mal, T-cell differentiation protein |
MAMLD1 | mastermind-like domain containing 1 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MPZL1 | myelin protein zero-like 1 |
MYH14 | myosin, heavy chain 14, non-muscle |
MYO1E | myosin IE |
NCAM1 | neural cell adhesion molecule 1 |
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
NLRP1 | NLR family, pyrin domain containing 1 |
NXN | nucleoredoxin |
PAX5 | paired box 5 |
PFN2 | profilin 2 |
PGBD5 | piggyBac transposable element derived 5 |
PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
PLS1 | plastin 1 |
POU4F1 | POU class 4 homeobox 1 |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
RAB6B | RAB6B, member RAS oncogene family |
RAD51B | RAD51 paralog B |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RIMS3 | regulating synaptic membrane exocytosis 3 |
RNASE4 | ribonuclease, RNase A family, 4 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SGCE | sarcoglycan, epsilon |
SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
SIGLEC7 | sialic acid binding Ig-like lectin 7 |
STAP1 | signal transducing adaptor family member 1 |
STAT4 | signal transducer and activator of transcription 4 |
STON1 | stonin 1 |
SYNM | synemin, intermediate filament protein |
TAOK2 | TAO kinase 2 |
TBC1D16 | TBC1 domain family, member 16 |
THAP10 | THAP domain containing 10 |
TNIK | TRAF2 and NCK interacting kinase |
TPMT | thiopurine S-methyltransferase |
TRIM62 | tripartite motif containing 62 |
TUBB2A | tubulin, beta 2A class IIa |
TUFT1 | tuftelin 1 |
ZC2HC1A | zinc finger, C2HC-type containing 1A |
Symbol | Name |
---|---|
ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
ASGR2 | asialoglycoprotein receptor 2 |
BAHCC1 | BAH domain and coiled-coil containing 1 |
BMP15 | bone morphogenetic protein 15 |
C17ORF53 | chromosome 17 open reading frame 53 |
C5 | complement component 5 |
CBX7 | chromobox homolog 7 |
CCDC94 | coiled-coil domain containing 94 |
CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CORT | cortistatin |
CRYGC | crystallin, gamma C |
CTDNEP1 | CTD nuclear envelope phosphatase 1 |
CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
DEAF1 | DEAF1 transcription factor |
DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
DSPP | dentin sialophosphoprotein |
DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
EPHB6 | EPH receptor B6 |
FAM120C | family with sequence similarity 120C |
FKBP9 | FK506 binding protein 9, 63 kDa |
FLT4 | fms-related tyrosine kinase 4 |
GMIP | GEM interacting protein |
GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
GPC3 | glypican 3 |
GPR27 | G protein-coupled receptor 27 |
GRIP2 | glutamate receptor interacting protein 2 |
GSTT1 | glutathione S-transferase theta 1 |
GSTZ1 | glutathione S-transferase zeta 1 |
GTF2I | general transcription factor IIi |
HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
HIST1H2AE | histone cluster 1, H2ae |
HIST1H2AI | histone cluster 1, H2ai |
HIST1H3B | histone cluster 1, H3b |
IL2 | interleukin 2 |
INF2 | inverted formin, FH2 and WH2 domain containing |
KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
KIAA1024 | KIAA1024 |
KIF17 | kinesin family member 17 |
LNPEP | leucyl/cystinyl aminopeptidase |
LOC257152 | uncharacterized LOC257152 |
MAB21L1 | mab-21-like 1 (C. elegans) |
MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
MEP1B | meprin A, beta |
METTL21B | methyltransferase like 21B |
MLPH | melanophilin |
MOCS3 | molybdenum cofactor synthesis 3 |
MTSS1L | metastasis suppressor 1-like |
NAG18 | NAG18 mRNA |
NEUROD4 | neuronal differentiation 4 |
NNAT | neuronatin |
NOD2 | nucleotide-binding oligomerization domain containing 2 |
NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
PCDH12 | protocadherin 12 |
PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
PIPOX | pipecolic acid oxidase |
PKD2L2 | polycystic kidney disease 2-like 2 |
PLA2G1B | phospholipase A2, group IB (pancreas) |
PLCB4 | phospholipase C, beta 4 |
PMF1 | polyamine-modulated factor 1 |
PRDM1 | PR domain containing 1, with ZNF domain |
PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
PYGB | phosphorylase, glycogen; brain |
REC8 | REC8 meiotic recombination protein |
RECQL4 | RecQ protein-like 4 |
RHBDD3 | rhomboid domain containing 3 |
RNF126P1 | ring finger protein 126 pseudogene 1 |
RUSC2 | RUN and SH3 domain containing 2 |
S1PR4 | sphingosine-1-phosphate receptor 4 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
SPATA1 | spermatogenesis associated 1 |
SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
TAS2R10 | taste receptor, type 2, member 10 |
TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
TEAD3 | TEA domain family member 3 |
TET3 | tet methylcytosine dioxygenase 3 |
TMC5 | transmembrane channel-like 5 |
TMEM209 | transmembrane protein 209 |
TPM3 | tropomyosin 3 |
TPRA1 | transmembrane protein, adipocyte asscociated 1 |
TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
TTC27 | tetratricopeptide repeat domain 27 |
UNG | uracil-DNA glycosylase |
USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
WDR6 | WD repeat domain 6 |
XAF1 | XIAP associated factor 1 |
ZNF34 | zinc finger protein 34 |
ZNF749 | zinc finger protein 749 |