trichostatin A-2949 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the trichostatin A-2949 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADGRL2 adhesion G protein-coupled receptor L2
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ANG angiogenin, ribonuclease, RNase A family, 5
ARMC9 armadillo repeat containing 9
ATP13A2 ATPase type 13A2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BIK BCL2-interacting killer (apoptosis-inducing)
BLVRA biliverdin reductase A
BMP6 bone morphogenetic protein 6
C5ORF45 chromosome 5 open reading frame 45
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CBX7 chromobox homolog 7
CD59 CD59 molecule, complement regulatory protein
CD70 CD70 molecule
CDC25C cell division cycle 25C
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPM carboxypeptidase M
CSNK1E casein kinase 1, epsilon
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DSP desmoplakin
EFNB2 ephrin-B2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHB2 EPH receptor B2
EPN2 epsin 2
EXPH5 exophilin 5
FAM65A family with sequence similarity 65, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF2 fibroblast growth factor 2 (basic)
FUCA1 fucosidase, alpha-L- 1, tissue
FZD3 frizzled class receptor 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCH1 GTP cyclohydrolase 1
GIPC1 GIPC PDZ domain containing family, member 1
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
HABP4 hyaluronan binding protein 4
HOXA5 homeobox A5
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ITGA7 integrin, alpha 7
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KDM7A lysine (K)-specific demethylase 7A
KIAA0040 KIAA0040
KIAA0226L KIAA0226-like
KIDINS220 kinase D-interacting substrate, 220kDa
KIF5C kinesin family member 5C
LHX2 LIM homeobox 2
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MARCKS myristoylated alanine-rich protein kinase C substrate
METRN meteorin, glial cell differentiation regulator
MKL2 MKL/myocardin-like 2
MPZL1 myelin protein zero-like 1
MTSS1 metastasis suppressor 1
MXD4 MAX dimerization protein 4
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCAM1 neural cell adhesion molecule 1
NPIPB15 nuclear pore complex interacting protein family, member B15
OLFML2A olfactomedin-like 2A
PADI2 peptidyl arginine deiminase, type II
PALLD palladin, cytoskeletal associated protein
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCGF2 polycomb group ring finger 2
PCNXL2 pecanex-like 2 (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PFKM phosphofructokinase, muscle
PFN2 profilin 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
POU4F1 POU class 4 homeobox 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTDSS2 phosphatidylserine synthase 2
RAB26 RAB26, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASE4 ribonuclease, RNase A family, 4
RPL13P5 ribosomal protein L13 pseudogene 5
SAMD4A sterile alpha motif domain containing 4A
SCARB2 scavenger receptor class B, member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SORBS3 sorbin and SH3 domain containing 3
SPINT1 serine peptidase inhibitor, Kunitz type 1
STON1 stonin 1
STXBP1 syntaxin binding protein 1
TAPT1 transmembrane anterior posterior transformation 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNIK TRAF2 and NCK interacting kinase
TPD52L1 tumor protein D52-like 1
TPMT thiopurine S-methyltransferase
TSPAN13 tetraspanin 13
UCN urocortin
ZER1 zyg-11 related, cell cycle regulator
ZNF232 zinc finger protein 232

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABHD4 abhydrolase domain containing 4
ACVR2B activin A receptor, type IIB
ADI1 acireductone dioxygenase 1
ALG3 ALG3, alpha-1,3- mannosyltransferase
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AVEN apoptosis, caspase activation inhibitor
BBS10 Bardet-Biedl syndrome 10
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C10ORF2 chromosome 10 open reading frame 2
C11ORF30 chromosome 11 open reading frame 30
C19ORF40 chromosome 19 open reading frame 40
CARD9 caspase recruitment domain family, member 9
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CD14 CD14 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIDEB cell death-inducing DFFA-like effector b
CLTCL1 clathrin, heavy chain-like 1
CXORF21 chromosome X open reading frame 21
DCPS decapping enzyme, scavenger
DENND2D DENN/MADD domain containing 2D
DOLK dolichol kinase
DUSP2 dual specificity phosphatase 2
E4F1 E4F transcription factor 1
ECHDC2 enoyl CoA hydratase domain containing 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELP6 elongator acetyltransferase complex subunit 6
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM136A family with sequence similarity 136, member A
FAM216A family with sequence similarity 216, member A
FBRS fibrosin
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR22 G protein-coupled receptor 22
GPR27 G protein-coupled receptor 27
GRAMD4 GRAM domain containing 4
GRWD1 glutamate-rich WD repeat containing 1
GYPC glycophorin C (Gerbich blood group)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2BO histone cluster 1, H2bo
HRAS Harvey rat sarcoma viral oncogene homolog
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IRX5 iroquois homeobox 5
ISG15 ISG15 ubiquitin-like modifier
KDM5C lysine (K)-specific demethylase 5C
KIAA0754 KIAA0754
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LMNB1 lamin B1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCM9 minichromosome maintenance complex component 9
MCRS1 microspherule protein 1
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
METTL8 methyltransferase like 8
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MX1 MX dynamin-like GTPase 1
NIP7 NIP7, nucleolar pre-rRNA processing protein
NME6 NME/NM23 nucleoside diphosphate kinase 6
NR1D2 nuclear receptor subfamily 1, group D, member 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PLA2G15 phospholipase A2, group XV
PNOC prepronociceptin
PPAN peter pan homolog (Drosophila)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RUSC2 RUN and SH3 domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SNHG20 small nucleolar RNA host gene 20
SP1 Sp1 transcription factor
SPI1 Spi-1 proto-oncogene
STAG1 stromal antigen 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TET3 tet methylcytosine dioxygenase 3
TMEM53 transmembrane protein 53
TRPS1 trichorhinophalangeal syndrome I
TSPAN32 tetraspanin 32
TTC27 tetratricopeptide repeat domain 27
UBIAD1 UbiA prenyltransferase domain containing 1
URM1 ubiquitin related modifier 1
VSIG4 V-set and immunoglobulin domain containing 4
XAF1 XIAP associated factor 1
ZNF236 zinc finger protein 236
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZNF804A zinc finger protein 804A
ZNF862 zinc finger protein 862