trichostatin A-2993 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the trichostatin A-2993 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ABHD6 abhydrolase domain containing 6
ADA adenosine deaminase
ADAM28 ADAM metallopeptidase domain 28
ADGRL2 adhesion G protein-coupled receptor L2
ADGRL3 adhesion G protein-coupled receptor L3
AMIGO2 adhesion molecule with Ig-like domain 2
ANG angiogenin, ribonuclease, RNase A family, 5
APLP2 amyloid beta (A4) precursor-like protein 2
AR androgen receptor
ARG2 arginase 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP9B ATPase, class II, type 9B
BCL6 B-cell CLL/lymphoma 6
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CD59 CD59 molecule, complement regulatory protein
CFP complement factor properdin
COL5A2 collagen, type V, alpha 2
CPM carboxypeptidase M
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CSRP2 cysteine and glycine-rich protein 2
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNMBP dynamin binding protein
DSP desmoplakin
DUSP4 dual specificity phosphatase 4
EFNA4 ephrin-A4
EFNB2 ephrin-B2
EIF5A2 eukaryotic translation initiation factor 5A2
ETV1 ets variant 1
F11R F11 receptor
FAM162A family with sequence similarity 162, member A
FDPS farnesyl diphosphate synthase
FHL1 four and a half LIM domains 1
FOXO1 forkhead box O1
GCH1 GTP cyclohydrolase 1
GLRX glutaredoxin (thioltransferase)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRAMD3 GRAM domain containing 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIPK3 homeodomain interacting protein kinase 3
HOXA1 homeobox A1
HPSE heparanase
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI30 interferon, gamma-inducible protein 30
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
INF2 inverted formin, FH2 and WH2 domain containing
KHK ketohexokinase (fructokinase)
KIAA0040 KIAA0040
KIF5C kinesin family member 5C
LAMA4 laminin, alpha 4
LEF1 lymphoid enhancer-binding factor 1
LOC730101 uncharacterized LOC730101
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2K3 mitogen-activated protein kinase kinase 3
MARCKS myristoylated alanine-rich protein kinase C substrate
MCTP2 multiple C2 domains, transmembrane 2
MPZL1 myelin protein zero-like 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
NCAM1 neural cell adhesion molecule 1
NDRG2 NDRG family member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
ONECUT2 one cut homeobox 2
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCDH17 protocadherin 17
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRL platelet-derived growth factor receptor-like
PDX1 pancreatic and duodenal homeobox 1
PIAS2 protein inhibitor of activated STAT, 2
PLCL1 phospholipase C-like 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POU4F1 POU class 4 homeobox 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC12A8 solute carrier family 12, member 8
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SSBP2 single-stranded DNA binding protein 2
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAP1 signal transducing adaptor family member 1
STARD5 StAR-related lipid transfer (START) domain containing 5
STON1 stonin 1
SVIL supervillin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPD52L1 tumor protein D52-like 1
TSPAN13 tetraspanin 13
TUBA4B tubulin, alpha 4b
TUBB2A tubulin, beta 2A class IIa
WISP3 WNT1 inducible signaling pathway protein 3
ZBTB17 zinc finger and BTB domain containing 17
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AVEN apoptosis, caspase activation inhibitor
BCAR3 breast cancer anti-estrogen resistance 3
BTF3P11 basic transcription factor 3 pseudogene 11
C16ORF59 chromosome 16 open reading frame 59
C8A complement component 8, alpha polypeptide
CARD9 caspase recruitment domain family, member 9
CASS4 Cas scaffolding protein family member 4
CCDC92 coiled-coil domain containing 92
CD79B CD79b molecule, immunoglobulin-associated beta
CDON cell adhesion associated, oncogene regulated
CELP carboxyl ester lipase pseudogene
CENPJ centromere protein J
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNN1 calponin 1, basic, smooth muscle
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
COQ6 coenzyme Q6 monooxygenase
CROT carnitine O-octanoyltransferase
CXCL2 chemokine (C-X-C motif) ligand 2
DHODH dihydroorotate dehydrogenase (quinone)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DSPP dentin sialophosphoprotein
DUSP2 dual specificity phosphatase 2
EBF2 early B-cell factor 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM106A family with sequence similarity 106, member A
FAM86C1 family with sequence similarity 86, member C1
FBXL7 F-box and leucine-rich repeat protein 7
FRMPD1 FERM and PDZ domain containing 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPC3 glypican 3
GPR35 G protein-coupled receptor 35
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HOXA2 homeobox A2
HOXC10 homeobox C10
HPR haptoglobin-related protein
HSPA1L heat shock 70kDa protein 1-like
IBSP integrin-binding sialoprotein
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGH immunoglobulin heavy locus
IL1R1 interleukin 1 receptor, type I
KCTD15 potassium channel tetramerization domain containing 15
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIF23 kinesin family member 23
KPTN kaptin (actin binding protein)
KRT12 keratin 12, type I
LTA lymphotoxin alpha
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MRPL44 mitochondrial ribosomal protein L44
MRPS18C mitochondrial ribosomal protein S18C
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MTSS1L metastasis suppressor 1-like
MUC2 mucin 2, oligomeric mucus/gel-forming
MYL5 myosin, light chain 5, regulatory
NR1D2 nuclear receptor subfamily 1, group D, member 2
OSBP2 oxysterol binding protein 2
PCDH12 protocadherin 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIR pirin (iron-binding nuclear protein)
PLA2G3 phospholipase A2, group III
PLAT plasminogen activator, tissue
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
RFPL1S RFPL1 antisense RNA 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCRT1 scratch family zinc finger 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SFRP5 secreted frizzled-related protein 5
SH2D4A SH2 domain containing 4A
SLC12A9 solute carrier family 12, member 9
SLC35F6 solute carrier family 35, member F6
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPATA1 spermatogenesis associated 1
SPATA2L spermatogenesis associated 2-like
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SYNDIG1 synapse differentiation inducing 1
TAS2R10 taste receptor, type 2, member 10
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFDP3 transcription factor Dp family, member 3
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM212 transmembrane protein 212
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSSC4 tumor suppressing subtransferable candidate 4
ZNF408 zinc finger protein 408
ZXDB zinc finger, X-linked, duplicated B