trichostatin A-364 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the trichostatin A-364 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ALOX5 arachidonate 5-lipoxygenase
ANO10 anoctamin 10
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGAP25 Rho GTPase activating protein 25
ARL4C ADP-ribosylation factor-like 4C
C16ORF58 chromosome 16 open reading frame 58
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CADM3 cell adhesion molecule 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCHCR1 coiled-coil alpha-helical rod protein 1
CD36 CD36 molecule (thrombospondin receptor)
CHRM4 cholinergic receptor, muscarinic 4
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CREB3 cAMP responsive element binding protein 3
CRIPT cysteine-rich PDZ-binding protein
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DDAH2 dimethylarginine dimethylaminohydrolase 2
DIO2 deiodinase, iodothyronine, type II
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DLEC1 deleted in lung and esophageal cancer 1
DNAH3 dynein, axonemal, heavy chain 3
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
ECI2 enoyl-CoA delta isomerase 2
ELF4 E74-like factor 4 (ets domain transcription factor)
EPX eosinophil peroxidase
ERMP1 endoplasmic reticulum metallopeptidase 1
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR1 fibroblast growth factor receptor 1
FKBP5 FK506 binding protein 5
FKBP8 FK506 binding protein 8, 38kDa
FLRT1 fibronectin leucine rich transmembrane protein 1
FN1 fibronectin 1
FOSL2 FOS-like antigen 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSCN1 fascin actin-bundling protein 1
FZD6 frizzled class receptor 6
GBAP1 glucosidase, beta, acid pseudogene 1
GDF11 growth differentiation factor 11
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
HBEGF heparin-binding EGF-like growth factor
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA4 heat shock 70kDa protein 4
IL19 interleukin 19
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL28 kelch-like family member 28
KSR1 kinase suppressor of ras 1
LPPR2 lipid phosphate phosphatase-related protein type 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MST1 macrophage stimulating 1
MVK mevalonate kinase
MYOZ3 myozenin 3
NDRG2 NDRG family member 2
NEK9 NIMA-related kinase 9
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NIPAL3 NIPA-like domain containing 3
NTAN1 N-terminal asparagine amidase
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE4B phosphodiesterase 4B, cAMP-specific
POGZ pogo transposable element with ZNF domain
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRB1 proline-rich protein BstNI subfamily 1
RAB6B RAB6B, member RAS oncogene family
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RHOC ras homolog family member C
RPS11 ribosomal protein S11
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SAP30 Sin3A-associated protein, 30kDa
SCYL3 SCY1-like 3 (S. cerevisiae)
SENP6 SUMO1/sentrin specific peptidase 6
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SNAI1 snail family zinc finger 1
STX1A syntaxin 1A (brain)
STX2 syntaxin 2
TBL1X transducin (beta)-like 1X-linked
TMEM132A transmembrane protein 132A
TMEM176A transmembrane protein 176A
TMEM45A transmembrane protein 45A
TMEM63A transmembrane protein 63A
TP53I3 tumor protein p53 inducible protein 3
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIB2 tribbles pseudokinase 2
TSPYL2 TSPY-like 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
YLPM1 YLP motif containing 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF219 zinc finger protein 219
ZNF287 zinc finger protein 287
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
AMT aminomethyltransferase
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
AVEN apoptosis, caspase activation inhibitor
AXIN1 axin 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BICC1 BicC family RNA binding protein 1
BRIX1 BRX1, biogenesis of ribosomes
BST1 bone marrow stromal cell antigen 1
C5ORF28 chromosome 5 open reading frame 28
C9ORF3 chromosome 9 open reading frame 3
CCDC177 coiled-coil domain containing 177
CCL19 chemokine (C-C motif) ligand 19
CD302 CD302 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COG7 component of oligomeric golgi complex 7
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDR2 discoidin domain receptor tyrosine kinase 2
DENND4C DENN/MADD domain containing 4C
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNASE1L3 deoxyribonuclease I-like 3
DOK3 docking protein 3
EMILIN2 elastin microfibril interfacer 2
ERF Ets2 repressor factor
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM189B family with sequence similarity 189, member B
FTCD formimidoyltransferase cyclodeaminase
GBE1 glucan (1,4-alpha-), branching enzyme 1
GCKR glucokinase (hexokinase 4) regulator
GDF5 growth differentiation factor 5
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GUSBP3 glucuronidase, beta pseudogene 3
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2AC histone cluster 1, H2ac
HMOX1 heme oxygenase 1
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFITM3 interferon induced transmembrane protein 3
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLHL3 kelch-like family member 3
KREMEN2 kringle containing transmembrane protein 2
LMNB1 lamin B1
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LRRC16A leucine rich repeat containing 16A
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPK3 mitogen-activated protein kinase 3
MISP mitotic spindle positioning
MLN motilin
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL19 mitochondrial ribosomal protein L19
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MYO19 myosin XIX
NELL2 NEL-like 2 (chicken)
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOL6 nucleolar protein 6 (RNA-associated)
NPPA natriuretic peptide A
NUBP1 nucleotide binding protein 1
OLFML3 olfactomedin-like 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR7A17 olfactory receptor, family 7, subfamily A, member 17
PAX1 paired box 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PFAS phosphoribosylformylglycinamidine synthase
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PGS1 phosphatidylglycerophosphate synthase 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLEK2 pleckstrin 2
PODNL1 podocan-like 1
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRMT3 protein arginine methyltransferase 3
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPRT protein tyrosine phosphatase, receptor type, T
PUS7 pseudouridylate synthase 7 (putative)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
QTRT1 queuine tRNA-ribosyltransferase 1
RPH3A rabphilin 3A
RPL23AP32 ribosomal protein L23a pseudogene 32
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SHPK sedoheptulokinase
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLIT2 slit homolog 2 (Drosophila)
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STAB2 stabilin 2
STAU2 staufen double-stranded RNA binding protein 2
SYMPK symplekin
SYNDIG1 synapse differentiation inducing 1
THRB thyroid hormone receptor, beta
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TTC27 tetratricopeptide repeat domain 27
TTC4 tetratricopeptide repeat domain 4
TUBA4B tubulin, alpha 4b
UNC93B1 unc-93 homolog B1 (C. elegans)
UNKL unkempt family zinc finger-like
ZNF304 zinc finger protein 304
ZNF580 zinc finger protein 580