Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the trichostatin A-5231 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
ADD3 | adducin 3 (gamma) |
AHNAK2 | AHNAK nucleoprotein 2 |
ALDOC | aldolase C, fructose-bisphosphate |
ARMCX2 | armadillo repeat containing, X-linked 2 |
BAIAP3 | BAI1-associated protein 3 |
CASC1 | cancer susceptibility candidate 1 |
CCNA1 | cyclin A1 |
CDH18 | cadherin 18, type 2 |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CEP112 | centrosomal protein 112kDa |
CLGN | calmegin |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CTGF | connective tissue growth factor |
CXADR | coxsackie virus and adenovirus receptor |
CYLD | cylindromatosis (turban tumor syndrome) |
CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 |
CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DIXDC1 | DIX domain containing 1 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DPYSL4 | dihydropyrimidinase-like 4 |
EFNB3 | ephrin-B3 |
EGR1 | early growth response 1 |
ELOVL4 | ELOVL fatty acid elongase 4 |
FAM105A | family with sequence similarity 105, member A |
FAM46C | family with sequence similarity 46, member C |
FKBP1B | FK506 binding protein 1B, 12.6 kDa |
FOS | FBJ murine osteosarcoma viral oncogene homolog |
FSCN1 | fascin actin-bundling protein 1 |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GEM | GTP binding protein overexpressed in skeletal muscle |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
GLDC | glycine dehydrogenase (decarboxylating) |
GLRX | glutaredoxin (thioltransferase) |
GRAMD1C | GRAM domain containing 1C |
GRK5 | G protein-coupled receptor kinase 5 |
GTF2B | general transcription factor IIB |
HBEGF | heparin-binding EGF-like growth factor |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
HSPA2 | heat shock 70kDa protein 2 |
IRF7 | interferon regulatory factor 7 |
KIF5C | kinesin family member 5C |
LIMA1 | LIM domain and actin binding 1 |
MAP1B | microtubule-associated protein 1B |
MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
MCOLN1 | mucolipin 1 |
MMD | monocyte to macrophage differentiation-associated |
NAP1L3 | nucleosome assembly protein 1-like 3 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NES | nestin |
NPC1 | Niemann-Pick disease, type C1 |
NXN | nucleoredoxin |
OASL | 2'-5'-oligoadenylate synthetase-like |
PADI3 | peptidyl arginine deiminase, type III |
PARP16 | poly (ADP-ribose) polymerase family, member 16 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PKNOX2 | PBX/knotted 1 homeobox 2 |
PLK3 | polo-like kinase 3 |
PMEL | premelanosome protein |
PRPH | peripherin |
PTRF | polymerase I and transcript release factor |
RAI2 | retinoic acid induced 2 |
RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RGS2 | regulator of G-protein signaling 2 |
RND1 | Rho family GTPase 1 |
RPL3L | ribosomal protein L3-like |
RTN2 | reticulon 2 |
RUNDC3B | RUN domain containing 3B |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SH3GL3 | SH3-domain GRB2-like 3 |
SIRT4 | sirtuin 4 |
SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
SORBS1 | sorbin and SH3 domain containing 1 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STXBP1 | syntaxin binding protein 1 |
SYT11 | synaptotagmin XI |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TMSB15A | thymosin beta 15a |
TUFT1 | tuftelin 1 |
ULBP2 | UL16 binding protein 2 |
WDR19 | WD repeat domain 19 |
WDR47 | WD repeat domain 47 |
WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
ZBTB18 | zinc finger and BTB domain containing 18 |
ZCCHC24 | zinc finger, CCHC domain containing 24 |
ZDHHC11 | zinc finger, DHHC-type containing 11 |
ZNF10 | zinc finger protein 10 |
ZNF204P | zinc finger protein 204, pseudogene |
Symbol | Name |
---|---|
ACIN1 | apoptotic chromatin condensation inducer 1 |
ACKR3 | atypical chemokine receptor 3 |
ADNP | activity-dependent neuroprotector homeobox |
AKAP8 | A kinase (PRKA) anchor protein 8 |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
BCAR3 | breast cancer anti-estrogen resistance 3 |
BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
C9ORF91 | chromosome 9 open reading frame 91 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCDC94 | coiled-coil domain containing 94 |
CCND1 | cyclin D1 |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CHMP6 | charged multivesicular body protein 6 |
CISH | cytokine inducible SH2-containing protein |
COIL | coilin |
CTCF | CCCTC-binding factor (zinc finger protein) |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
CUL1 | cullin 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
E2F8 | E2F transcription factor 8 |
EFNA1 | ephrin-A1 |
EGR3 | early growth response 3 |
ELF4 | E74-like factor 4 (ets domain transcription factor) |
EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
ERBB2IP | erbb2 interacting protein |
FAIM | Fas apoptotic inhibitory molecule |
FAM57A | family with sequence similarity 57, member A |
FJX1 | four jointed box 1 (Drosophila) |
FOXA1 | forkhead box A1 |
FOXC1 | forkhead box C1 |
GABPB1 | GA binding protein transcription factor, beta subunit 1 |
GATA3 | GATA binding protein 3 |
HIRIP3 | HIRA interacting protein 3 |
HMGXB4 | HMG box domain containing 4 |
INHBB | inhibin, beta B |
IRS1 | insulin receptor substrate 1 |
IRX4 | iroquois homeobox 4 |
IRX5 | iroquois homeobox 5 |
KAT2A | K(lysine) acetyltransferase 2A |
KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
KEAP1 | kelch-like ECH-associated protein 1 |
KIAA0125 | KIAA0125 |
LAMA5 | laminin, alpha 5 |
LMNB1 | lamin B1 |
LY6G5C | lymphocyte antigen 6 complex, locus G5C |
MCM9 | minichromosome maintenance complex component 9 |
MEPCE | methylphosphate capping enzyme |
METTL8 | methyltransferase like 8 |
MSL1 | male-specific lethal 1 homolog (Drosophila) |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NARFL | nuclear prelamin A recognition factor-like |
NRIP1 | nuclear receptor interacting protein 1 |
P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
POGK | pogo transposable element with KRAB domain |
PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
PRR15L | proline rich 15-like |
PUS1 | pseudouridylate synthase 1 |
RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
SETD1B | SET domain containing 1B |
SFMBT1 | Scm-like with four mbt domains 1 |
SH2D4A | SH2 domain containing 4A |
SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
SMAD7 | SMAD family member 7 |
SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
SMYD5 | SMYD family member 5 |
SNHG20 | small nucleolar RNA host gene 20 |
SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
SRSF4 | serine/arginine-rich splicing factor 4 |
STC2 | stanniocalcin 2 |
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
TCERG1 | transcription elongation regulator 1 |
TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
TGIF1 | TGFB-induced factor homeobox 1 |
TMEM223 | transmembrane protein 223 |
TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
TNS3 | tensin 3 |
TRIB1 | tribbles pseudokinase 1 |
TRIB3 | tribbles pseudokinase 3 |
TRIM16 | tripartite motif containing 16 |
TRIM8 | tripartite motif containing 8 |
TSKU | tsukushi, small leucine rich proteoglycan |
UBL4A | ubiquitin-like 4A |
UBTF | upstream binding transcription factor, RNA polymerase I |
VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
WDR74 | WD repeat domain 74 |
XBP1 | X-box binding protein 1 |
YAP1 | Yes-associated protein 1 |
ZBED1 | zinc finger, BED-type containing 1 |
ZHX2 | zinc fingers and homeoboxes 2 |
ZIC1 | Zic family member 1 |
ZMIZ1 | zinc finger, MIZ-type containing 1 |
ZNF692 | zinc finger protein 692 |
ZNF787 | zinc finger protein 787 |