Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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200 genes differentially expressed following the trichostatin A-5908 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABAT | 4-aminobutyrate aminotransferase |
ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
ACOT7 | acyl-CoA thioesterase 7 |
AGTR1 | angiotensin II receptor, type 1 |
AHR | aryl hydrocarbon receptor |
AMDHD2 | amidohydrolase domain containing 2 |
ANGPTL4 | angiopoietin-like 4 |
AQP3 | aquaporin 3 (Gill blood group) |
ARG2 | arginase 2 |
ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
ASMTL | acetylserotonin O-methyltransferase-like |
AVPI1 | arginine vasopressin-induced 1 |
BAIAP2 | BAI1-associated protein 2 |
BAMBI | BMP and activin membrane-bound inhibitor |
BCL6 | B-cell CLL/lymphoma 6 |
C1QL1 | complement component 1, q subcomponent-like 1 |
C5ORF45 | chromosome 5 open reading frame 45 |
CA5B | carbonic anhydrase VB, mitochondrial |
CD70 | CD70 molecule |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CORO1A | coronin, actin binding protein, 1A |
CPM | carboxypeptidase M |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CTGF | connective tissue growth factor |
CTH | cystathionine gamma-lyase |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 |
DENND3 | DENN/MADD domain containing 3 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DUSP1 | dual specificity phosphatase 1 |
DUSP10 | dual specificity phosphatase 10 |
EFNA3 | ephrin-A3 |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
ELOVL4 | ELOVL fatty acid elongase 4 |
EPPK1 | epiplakin 1 |
FABP4 | fatty acid binding protein 4, adipocyte |
FAM134B | family with sequence similarity 134, member B |
FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
GCDH | glutaryl-CoA dehydrogenase |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
GLS | glutaminase |
GMPR | guanosine monophosphate reductase |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IL11 | interleukin 11 |
INSIG1 | insulin induced gene 1 |
IRF6 | interferon regulatory factor 6 |
JUNB | jun B proto-oncogene |
KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
KIF5C | kinesin family member 5C |
LIPE | lipase, hormone-sensitive |
LMCD1 | LIM and cysteine-rich domains 1 |
LPPR4 | lipid phosphate phosphatase-related protein type 4 |
LTB4R | leukotriene B4 receptor |
MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
MAPT | microtubule-associated protein tau |
MERTK | MER proto-oncogene, tyrosine kinase |
MMP1 | matrix metallopeptidase 1 |
MOCS3 | molybdenum cofactor synthesis 3 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NEU1 | sialidase 1 (lysosomal sialidase) |
NPC1 | Niemann-Pick disease, type C1 |
OASL | 2'-5'-oligoadenylate synthetase-like |
PCDH17 | protocadherin 17 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PELI1 | pellino E3 ubiquitin protein ligase 1 |
PKP2 | plakophilin 2 |
PLXNA3 | plexin A3 |
RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
RGCC | regulator of cell cycle |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RGS17 | regulator of G-protein signaling 17 |
RGS4 | regulator of G-protein signaling 4 |
RND1 | Rho family GTPase 1 |
RNF24 | ring finger protein 24 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SELPLG | selectin P ligand |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SH3GL2 | SH3-domain GRB2-like 2 |
SH3GL3 | SH3-domain GRB2-like 3 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SNAP23 | synaptosomal-associated protein, 23kDa |
SORBS1 | sorbin and SH3 domain containing 1 |
SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
STARD5 | StAR-related lipid transfer (START) domain containing 5 |
STC1 | stanniocalcin 1 |
SYT1 | synaptotagmin I |
SYT11 | synaptotagmin XI |
TAOK3 | TAO kinase 3 |
THEMIS2 | thymocyte selection associated family member 2 |
TJP3 | tight junction protein 3 |
TRAIP | TRAF interacting protein |
TUBB2B | tubulin, beta 2B class IIb |
TUFT1 | tuftelin 1 |
URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
Symbol | Name |
---|---|
ADGRG6 | adhesion G protein-coupled receptor G6 |
ADNP | activity-dependent neuroprotector homeobox |
ARSJ | arylsulfatase family, member J |
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
BCAR3 | breast cancer anti-estrogen resistance 3 |
C19ORF40 | chromosome 19 open reading frame 40 |
C19ORF54 | chromosome 19 open reading frame 54 |
C7ORF49 | chromosome 7 open reading frame 49 |
C9ORF40 | chromosome 9 open reading frame 40 |
CASD1 | CAS1 domain containing 1 |
CBR3 | carbonyl reductase 3 |
CCNJ | cyclin J |
CDC7 | cell division cycle 7 |
CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
CLCF1 | cardiotrophin-like cytokine factor 1 |
CTCF | CCCTC-binding factor (zinc finger protein) |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
CUL1 | cullin 1 |
CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
DEPDC1 | DEP domain containing 1 |
FJX1 | four jointed box 1 (Drosophila) |
FOSL1 | FOS-like antigen 1 |
FOXA1 | forkhead box A1 |
FOXC1 | forkhead box C1 |
FRS3 | fibroblast growth factor receptor substrate 3 |
FST | follistatin |
GABPB1 | GA binding protein transcription factor, beta subunit 1 |
GPR87 | G protein-coupled receptor 87 |
GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
H2AFY2 | H2A histone family, member Y2 |
HAS2 | hyaluronan synthase 2 |
HDAC7 | histone deacetylase 7 |
HIST1H4E | histone cluster 1, H4e |
HMGA2 | high mobility group AT-hook 2 |
HOXA2 | homeobox A2 |
HOXA4 | homeobox A4 |
INHBB | inhibin, beta B |
IRS1 | insulin receptor substrate 1 |
KAT6B | K(lysine) acetyltransferase 6B |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
KCTD17 | potassium channel tetramerization domain containing 17 |
KDM8 | lysine (K)-specific demethylase 8 |
KEAP1 | kelch-like ECH-associated protein 1 |
KIAA1107 | KIAA1107 |
KIF14 | kinesin family member 14 |
KIRREL | kin of IRRE like (Drosophila) |
LIF | leukemia inhibitory factor |
LMNB1 | lamin B1 |
LPAR1 | lysophosphatidic acid receptor 1 |
LUC7L2 | LUC7-like 2 (S. cerevisiae) |
LY6G5C | lymphocyte antigen 6 complex, locus G5C |
MEPCE | methylphosphate capping enzyme |
MRPL44 | mitochondrial ribosomal protein L44 |
MTRF1 | mitochondrial translational release factor 1 |
NDP | Norrie disease (pseudoglioma) |
NHEJ1 | nonhomologous end-joining factor 1 |
NMI | N-myc (and STAT) interactor |
NRIP1 | nuclear receptor interacting protein 1 |
NSD1 | nuclear receptor binding SET domain protein 1 |
P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
PALMD | palmdelphin |
PAN2 | PAN2 poly(A) specific ribonuclease subunit |
PPAP2B | phosphatidic acid phosphatase type 2B |
PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 |
PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
RBM4B | RNA binding motif protein 4B |
RIN2 | Ras and Rab interactor 2 |
RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SETD1B | SET domain containing 1B |
SFMBT1 | Scm-like with four mbt domains 1 |
SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
SIM2 | single-minded family bHLH transcription factor 2 |
SLC12A8 | solute carrier family 12, member 8 |
SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
SMAGP | small cell adhesion glycoprotein |
SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
SOGA1 | suppressor of glucose, autophagy associated 1 |
SRSF4 | serine/arginine-rich splicing factor 4 |
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
TMC5 | transmembrane channel-like 5 |
TMEM121 | transmembrane protein 121 |
TRIB3 | tribbles pseudokinase 3 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
UBTF | upstream binding transcription factor, RNA polymerase I |
VEGFC | vascular endothelial growth factor C |
VN1R1 | vomeronasal 1 receptor 1 |
ZBED1 | zinc finger, BED-type containing 1 |
ZBTB1 | zinc finger and BTB domain containing 1 |
ZC3H4 | zinc finger CCCH-type containing 4 |
ZNF165 | zinc finger protein 165 |
ZNF215 | zinc finger protein 215 |
ZNF227 | zinc finger protein 227 |
ZNF33B | zinc finger protein 33B |
ZNF446 | zinc finger protein 446 |
ZNF76 | zinc finger protein 76 |
ZSCAN31 | zinc finger and SCAN domain containing 31 |