Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the trichostatin A-5940 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
AHR | aryl hydrocarbon receptor |
ANGPTL4 | angiopoietin-like 4 |
AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
AQP3 | aquaporin 3 (Gill blood group) |
ARC | activity-regulated cytoskeleton-associated protein |
AREG | amphiregulin |
ARG2 | arginase 2 |
ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
ASMTL | acetylserotonin O-methyltransferase-like |
AVPI1 | arginine vasopressin-induced 1 |
BAIAP2 | BAI1-associated protein 2 |
BAMBI | BMP and activin membrane-bound inhibitor |
BEX1 | brain expressed, X-linked 1 |
BMP4 | bone morphogenetic protein 4 |
BMP6 | bone morphogenetic protein 6 |
C18ORF8 | chromosome 18 open reading frame 8 |
CA5B | carbonic anhydrase VB, mitochondrial |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CORO1A | coronin, actin binding protein, 1A |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
CTGF | connective tissue growth factor |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DENND3 | DENN/MADD domain containing 3 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
DPYSL4 | dihydropyrimidinase-like 4 |
DUSP1 | dual specificity phosphatase 1 |
DUSP10 | dual specificity phosphatase 10 |
EFNA4 | ephrin-A4 |
EGR2 | early growth response 2 |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
ELOVL4 | ELOVL fatty acid elongase 4 |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
FABP4 | fatty acid binding protein 4, adipocyte |
FAM69A | family with sequence similarity 69, member A |
GLCE | glucuronic acid epimerase |
GLS | glutaminase |
GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IL11 | interleukin 11 |
INSIG1 | insulin induced gene 1 |
IRF6 | interferon regulatory factor 6 |
IRS2 | insulin receptor substrate 2 |
KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
KIF5C | kinesin family member 5C |
KRT86 | keratin 86, type II |
LMCD1 | LIM and cysteine-rich domains 1 |
LOC157562 | uncharacterized LOC157562 |
LPPR4 | lipid phosphate phosphatase-related protein type 4 |
MAP2K3 | mitogen-activated protein kinase kinase 3 |
MAPT | microtubule-associated protein tau |
MERTK | MER proto-oncogene, tyrosine kinase |
MLF1 | myeloid leukemia factor 1 |
MMP1 | matrix metallopeptidase 1 |
NME5 | NME/NM23 family member 5 |
NMT2 | N-myristoyltransferase 2 |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
PCDH9 | protocadherin 9 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
PKP2 | plakophilin 2 |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PRPH | peripherin |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
RAI2 | retinoic acid induced 2 |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RGS4 | regulator of G-protein signaling 4 |
RHOB | ras homolog family member B |
RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SH3GL3 | SH3-domain GRB2-like 3 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STC1 | stanniocalcin 1 |
STK17B | serine/threonine kinase 17b |
STON1 | stonin 1 |
SYT1 | synaptotagmin I |
SYT11 | synaptotagmin XI |
TAOK3 | TAO kinase 3 |
TBC1D16 | TBC1 domain family, member 16 |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TRAFD1 | TRAF-type zinc finger domain containing 1 |
TRIM62 | tripartite motif containing 62 |
TUBB2B | tubulin, beta 2B class IIb |
TUFT1 | tuftelin 1 |
URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
VWA1 | von Willebrand factor A domain containing 1 |
ZMIZ2 | zinc finger, MIZ-type containing 2 |
Symbol | Name |
---|---|
ADNP | activity-dependent neuroprotector homeobox |
AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
ARHGAP11A | Rho GTPase activating protein 11A |
ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
AXIN1 | axin 1 |
BCAR3 | breast cancer anti-estrogen resistance 3 |
BCL7A | B-cell CLL/lymphoma 7A |
BNC2 | basonuclin 2 |
CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
CASD1 | CAS1 domain containing 1 |
CBR3 | carbonyl reductase 3 |
CCDC94 | coiled-coil domain containing 94 |
CLCF1 | cardiotrophin-like cytokine factor 1 |
COG7 | component of oligomeric golgi complex 7 |
COIL | coilin |
CTCF | CCCTC-binding factor (zinc finger protein) |
CUL1 | cullin 1 |
CYTH2 | cytohesin 2 |
DEPDC1 | DEP domain containing 1 |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
DUSP4 | dual specificity phosphatase 4 |
ELP3 | elongator acetyltransferase complex subunit 3 |
ESM1 | endothelial cell-specific molecule 1 |
FJX1 | four jointed box 1 (Drosophila) |
FOSL1 | FOS-like antigen 1 |
FOXA1 | forkhead box A1 |
FST | follistatin |
GABPB1 | GA binding protein transcription factor, beta subunit 1 |
GBX2 | gastrulation brain homeobox 2 |
GMEB1 | glucocorticoid modulatory element binding protein 1 |
GPR87 | G protein-coupled receptor 87 |
GRPR | gastrin-releasing peptide receptor |
GTF2IRD1 | GTF2I repeat domain containing 1 |
GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
HAS2 | hyaluronan synthase 2 |
HMGA2 | high mobility group AT-hook 2 |
IL4R | interleukin 4 receptor |
IL7R | interleukin 7 receptor |
INHBB | inhibin, beta B |
KAT6B | K(lysine) acetyltransferase 6B |
KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
KCTD15 | potassium channel tetramerization domain containing 15 |
KEAP1 | kelch-like ECH-associated protein 1 |
KIRREL | kin of IRRE like (Drosophila) |
LIF | leukemia inhibitory factor |
LPAR1 | lysophosphatidic acid receptor 1 |
LRRC41 | leucine rich repeat containing 41 |
LRRC61 | leucine rich repeat containing 61 |
MCM9 | minichromosome maintenance complex component 9 |
MEPCE | methylphosphate capping enzyme |
MPDU1 | mannose-P-dolichol utilization defect 1 |
MX1 | MX dynamin-like GTPase 1 |
NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
NRIP1 | nuclear receptor interacting protein 1 |
NTSR1 | neurotensin receptor 1 (high affinity) |
PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
PAX6 | paired box 6 |
PEF1 | penta-EF-hand domain containing 1 |
PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
PLK1 | polo-like kinase 1 |
POGK | pogo transposable element with KRAB domain |
PPAP2B | phosphatidic acid phosphatase type 2B |
PPCDC | phosphopantothenoylcysteine decarboxylase |
PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
RBM4B | RNA binding motif protein 4B |
RIN2 | Ras and Rab interactor 2 |
SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SETD1B | SET domain containing 1B |
SFMBT1 | Scm-like with four mbt domains 1 |
SIM2 | single-minded family bHLH transcription factor 2 |
SLC35F2 | solute carrier family 35, member F2 |
SMG9 | SMG9 nonsense mediated mRNA decay factor |
SMYD5 | SMYD family member 5 |
SNX5 | sorting nexin 5 |
SOX12 | SRY (sex determining region Y)-box 12 |
SRSF4 | serine/arginine-rich splicing factor 4 |
TCEAL1 | transcription elongation factor A (SII)-like 1 |
TEP1 | telomerase-associated protein 1 |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
TMC7 | transmembrane channel-like 7 |
TMEM53 | transmembrane protein 53 |
TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
TOE1 | target of EGR1, member 1 (nuclear) |
TRIB3 | tribbles pseudokinase 3 |
TSKU | tsukushi, small leucine rich proteoglycan |
USP21 | ubiquitin specific peptidase 21 |
VEGFC | vascular endothelial growth factor C |
WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
ZBED1 | zinc finger, BED-type containing 1 |
ZC3H4 | zinc finger CCCH-type containing 4 |
ZMYM3 | zinc finger, MYM-type 3 |
ZNF239 | zinc finger protein 239 |
ZNF32 | zinc finger protein 32 |
ZNF532 | zinc finger protein 532 |
ZNF787 | zinc finger protein 787 |
ZSCAN31 | zinc finger and SCAN domain containing 31 |