Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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200 genes differentially expressed following the trichostatin A-5981 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AADAC | arylacetamide deacetylase |
ABAT | 4-aminobutyrate aminotransferase |
ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
AGTR1 | angiotensin II receptor, type 1 |
AIM1L | absent in melanoma 1-like |
AMBRA1 | autophagy/beclin-1 regulator 1 |
ANGPTL4 | angiopoietin-like 4 |
AQP3 | aquaporin 3 (Gill blood group) |
ARC | activity-regulated cytoskeleton-associated protein |
AVPI1 | arginine vasopressin-induced 1 |
BAIAP2 | BAI1-associated protein 2 |
BAMBI | BMP and activin membrane-bound inhibitor |
CA5B | carbonic anhydrase VB, mitochondrial |
CACYBP | calcyclin binding protein |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CFAP69 | cilia and flagella associated protein 69 |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
CLDN1 | claudin 1 |
CLTCL1 | clathrin, heavy chain-like 1 |
COL11A2 | collagen, type XI, alpha 2 |
CORO1A | coronin, actin binding protein, 1A |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CTGF | connective tissue growth factor |
CTH | cystathionine gamma-lyase |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
DENND3 | DENN/MADD domain containing 3 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DUSP1 | dual specificity phosphatase 1 |
DUSP10 | dual specificity phosphatase 10 |
EDNRA | endothelin receptor type A |
EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
EFNA3 | ephrin-A3 |
EGR2 | early growth response 2 |
ELOVL4 | ELOVL fatty acid elongase 4 |
FABP4 | fatty acid binding protein 4, adipocyte |
FAM102A | family with sequence similarity 102, member A |
FAM110B | family with sequence similarity 110, member B |
FAM134B | family with sequence similarity 134, member B |
FAM188A | family with sequence similarity 188, member A |
FOS | FBJ murine osteosarcoma viral oncogene homolog |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
GLCE | glucuronic acid epimerase |
GMPR | guanosine monophosphate reductase |
GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
IL7 | interleukin 7 |
ING2 | inhibitor of growth family, member 2 |
INSIG1 | insulin induced gene 1 |
KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
KIAA0895 | KIAA0895 |
KIF5C | kinesin family member 5C |
KLF2 | Kruppel-like factor 2 |
LINC00341 | long intergenic non-protein coding RNA 341 |
LMCD1 | LIM and cysteine-rich domains 1 |
LPPR4 | lipid phosphate phosphatase-related protein type 4 |
MAK | male germ cell-associated kinase |
MERTK | MER proto-oncogene, tyrosine kinase |
MMP1 | matrix metallopeptidase 1 |
MMP10 | matrix metallopeptidase 10 |
MMP13 | matrix metallopeptidase 13 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
NPC1 | Niemann-Pick disease, type C1 |
OASL | 2'-5'-oligoadenylate synthetase-like |
PDE4DIP | phosphodiesterase 4D interacting protein |
PLAG1 | pleiomorphic adenoma gene 1 |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PRPH | peripherin |
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
RAI2 | retinoic acid induced 2 |
RANBP1 | RAN binding protein 1 |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RPL37A | ribosomal protein L37a |
RUNDC3B | RUN domain containing 3B |
SAP30 | Sin3A-associated protein, 30kDa |
SCD5 | stearoyl-CoA desaturase 5 |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SH3GL3 | SH3-domain GRB2-like 3 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STC1 | stanniocalcin 1 |
STOM | stomatin |
STON1 | stonin 1 |
SYT11 | synaptotagmin XI |
TBC1D2 | TBC1 domain family, member 2 |
TBXA2R | thromboxane A2 receptor |
TFEC | transcription factor EC |
TJP3 | tight junction protein 3 |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TUBB2B | tubulin, beta 2B class IIb |
TUFT1 | tuftelin 1 |
UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
WDR19 | WD repeat domain 19 |
WSB1 | WD repeat and SOCS box containing 1 |
ZFP36 | ZFP36 ring finger protein |
Symbol | Name |
---|---|
AAR2 | AAR2 splicing factor homolog (S. cerevisiae) |
ADGRG2 | adhesion G protein-coupled receptor G2 |
ADGRG6 | adhesion G protein-coupled receptor G6 |
ADNP | activity-dependent neuroprotector homeobox |
ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
ARSJ | arylsulfatase family, member J |
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
BAG2 | BCL2-associated athanogene 2 |
BCAR3 | breast cancer anti-estrogen resistance 3 |
C11ORF63 | chromosome 11 open reading frame 63 |
C1RL | complement component 1, r subcomponent-like |
C7ORF49 | chromosome 7 open reading frame 49 |
C8ORF44 | chromosome 8 open reading frame 44 |
CBR3 | carbonyl reductase 3 |
CCDC94 | coiled-coil domain containing 94 |
CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
COA7 | cytochrome c oxidase assembly factor 7 (putative) |
CUL1 | cullin 1 |
DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
DEPDC1 | DEP domain containing 1 |
DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
DUSP4 | dual specificity phosphatase 4 |
ELF1 | E74-like factor 1 (ets domain transcription factor) |
FADD | Fas (TNFRSF6)-associated via death domain |
FAM169A | family with sequence similarity 169, member A |
FAM57A | family with sequence similarity 57, member A |
FAM60A | family with sequence similarity 60, member A |
FJX1 | four jointed box 1 (Drosophila) |
FOSL1 | FOS-like antigen 1 |
FOXA1 | forkhead box A1 |
FST | follistatin |
GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
GABPB1 | GA binding protein transcription factor, beta subunit 1 |
GBX2 | gastrulation brain homeobox 2 |
GIN1 | gypsy retrotransposon integrase 1 |
HAS2 | hyaluronan synthase 2 |
HIRIP3 | HIRA interacting protein 3 |
HMGA2 | high mobility group AT-hook 2 |
HMGB3 | high mobility group box 3 |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
IL7R | interleukin 7 receptor |
INHBB | inhibin, beta B |
ITPKB | inositol-trisphosphate 3-kinase B |
KAT6B | K(lysine) acetyltransferase 6B |
KEAP1 | kelch-like ECH-associated protein 1 |
LIF | leukemia inhibitory factor |
LMNB1 | lamin B1 |
MEPCE | methylphosphate capping enzyme |
MTA2 | metastasis associated 1 family, member 2 |
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
NHEJ1 | nonhomologous end-joining factor 1 |
NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
NRIP1 | nuclear receptor interacting protein 1 |
NUP62 | nucleoporin 62kDa |
PARP12 | poly (ADP-ribose) polymerase family, member 12 |
PCOLCE | procollagen C-endopeptidase enhancer |
PLAU | plasminogen activator, urokinase |
PLK1 | polo-like kinase 1 |
POGK | pogo transposable element with KRAB domain |
POMT2 | protein-O-mannosyltransferase 2 |
PPAP2B | phosphatidic acid phosphatase type 2B |
PPCDC | phosphopantothenoylcysteine decarboxylase |
PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 |
PTGFR | prostaglandin F receptor (FP) |
RBM4B | RNA binding motif protein 4B |
RIN2 | Ras and Rab interactor 2 |
SCAF8 | SR-related CTD-associated factor 8 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SETD1B | SET domain containing 1B |
SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
SMAGP | small cell adhesion glycoprotein |
SMG9 | SMG9 nonsense mediated mRNA decay factor |
SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
SOX12 | SRY (sex determining region Y)-box 12 |
SRSF4 | serine/arginine-rich splicing factor 4 |
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
SYNPO | synaptopodin |
TEP1 | telomerase-associated protein 1 |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
TGIF1 | TGFB-induced factor homeobox 1 |
TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
TMC5 | transmembrane channel-like 5 |
TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
TRABD | TraB domain containing |
TRIB3 | tribbles pseudokinase 3 |
URGCP | upregulator of cell proliferation |
USP21 | ubiquitin specific peptidase 21 |
VEGFC | vascular endothelial growth factor C |
VWA9 | von Willebrand factor A domain containing 9 |
YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
ZC3H4 | zinc finger CCCH-type containing 4 |
ZNF532 | zinc finger protein 532 |
ZNF692 | zinc finger protein 692 |
ZNF711 | zinc finger protein 711 |
ZNF76 | zinc finger protein 76 |