Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the trichostatin A-6579 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD6 | abhydrolase domain containing 6 |
ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
ADM | adrenomedullin |
AHNAK2 | AHNAK nucleoprotein 2 |
BAIAP3 | BAI1-associated protein 3 |
CCDC176 | coiled-coil domain containing 176 |
CCDC28A | coiled-coil domain containing 28A |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
CORO1A | coronin, actin binding protein, 1A |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CSRP2 | cysteine and glycine-rich protein 2 |
CXADR | coxsackie virus and adenovirus receptor |
CYLD | cylindromatosis (turban tumor syndrome) |
CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 |
CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
DFNB31 | deafness, autosomal recessive 31 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
DPYSL4 | dihydropyrimidinase-like 4 |
EFNA3 | ephrin-A3 |
ELOVL4 | ELOVL fatty acid elongase 4 |
EPOR | erythropoietin receptor |
FKBP1B | FK506 binding protein 1B, 12.6 kDa |
FSCN1 | fascin actin-bundling protein 1 |
GCHFR | GTP cyclohydrolase I feedback regulator |
GEM | GTP binding protein overexpressed in skeletal muscle |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
GLCE | glucuronic acid epimerase |
GLDC | glycine dehydrogenase (decarboxylating) |
GLRX | glutaredoxin (thioltransferase) |
GRAMD1C | GRAM domain containing 1C |
GRK5 | G protein-coupled receptor kinase 5 |
GTF2B | general transcription factor IIB |
HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
HSPA2 | heat shock 70kDa protein 2 |
IGFBP3 | insulin-like growth factor binding protein 3 |
IRF7 | interferon regulatory factor 7 |
ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
JAG1 | jagged 1 |
JAKMIP2 | janus kinase and microtubule interacting protein 2 |
KIF21B | kinesin family member 21B |
KIF5C | kinesin family member 5C |
LIMA1 | LIM domain and actin binding 1 |
LINC00341 | long intergenic non-protein coding RNA 341 |
MAN1C1 | mannosidase, alpha, class 1C, member 1 |
MAP1B | microtubule-associated protein 1B |
MAP2K3 | mitogen-activated protein kinase kinase 3 |
MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
MARK4 | MAP/microtubule affinity-regulating kinase 4 |
MAST3 | microtubule associated serine/threonine kinase 3 |
MCOLN1 | mucolipin 1 |
MXRA7 | matrix-remodelling associated 7 |
NDRG1 | N-myc downstream regulated 1 |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
NME7 | NME/NM23 family member 7 |
NPC1 | Niemann-Pick disease, type C1 |
NXN | nucleoredoxin |
OASL | 2'-5'-oligoadenylate synthetase-like |
PADI3 | peptidyl arginine deiminase, type III |
PAIP2B | poly(A) binding protein interacting protein 2B |
PCDH9 | protocadherin 9 |
PER1 | period circadian clock 1 |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
PRPH | peripherin |
PTRF | polymerase I and transcript release factor |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RGS2 | regulator of G-protein signaling 2 |
RHOBTB2 | Rho-related BTB domain containing 2 |
RPL3L | ribosomal protein L3-like |
RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
RUNDC3B | RUN domain containing 3B |
SAPCD1 | suppressor APC domain containing 1 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SH3GL3 | SH3-domain GRB2-like 3 |
SIRT4 | sirtuin 4 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STON1 | stonin 1 |
SYT11 | synaptotagmin XI |
TBXA2R | thromboxane A2 receptor |
TMSB15A | thymosin beta 15a |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TUBA4A | tubulin, alpha 4a |
TUFT1 | tuftelin 1 |
TXNIP | thioredoxin interacting protein |
USB1 | U6 snRNA biogenesis 1 |
WDR19 | WD repeat domain 19 |
WDR47 | WD repeat domain 47 |
ZCCHC24 | zinc finger, CCHC domain containing 24 |
ZDHHC11 | zinc finger, DHHC-type containing 11 |
ZNF204P | zinc finger protein 204, pseudogene |
Symbol | Name |
---|---|
ACKR3 | atypical chemokine receptor 3 |
ADGRA3 | adhesion G protein-coupled receptor A3 |
ADNP | activity-dependent neuroprotector homeobox |
AKAP8 | A kinase (PRKA) anchor protein 8 |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
BATF | basic leucine zipper transcription factor, ATF-like |
BCAR3 | breast cancer anti-estrogen resistance 3 |
BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
C11ORF68 | chromosome 11 open reading frame 68 |
C1ORF106 | chromosome 1 open reading frame 106 |
C9ORF91 | chromosome 9 open reading frame 91 |
CALHM2 | calcium homeostasis modulator 2 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCND1 | cyclin D1 |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
COIL | coilin |
CTCF | CCCTC-binding factor (zinc finger protein) |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
CUL1 | cullin 1 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
DCLRE1A | DNA cross-link repair 1A |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EFNA1 | ephrin-A1 |
EGR3 | early growth response 3 |
ELF4 | E74-like factor 4 (ets domain transcription factor) |
ERBB2IP | erbb2 interacting protein |
FAM57A | family with sequence similarity 57, member A |
FJX1 | four jointed box 1 (Drosophila) |
FOXA1 | forkhead box A1 |
GATA3 | GATA binding protein 3 |
GMEB2 | glucocorticoid modulatory element binding protein 2 |
GTF2IRD1 | GTF2I repeat domain containing 1 |
HIRIP3 | HIRA interacting protein 3 |
HNRNPF | heterogeneous nuclear ribonucleoprotein F |
HOXC11 | homeobox C11 |
INHBB | inhibin, beta B |
IRS1 | insulin receptor substrate 1 |
IRX5 | iroquois homeobox 5 |
JUNB | jun B proto-oncogene |
KCTD15 | potassium channel tetramerization domain containing 15 |
KEAP1 | kelch-like ECH-associated protein 1 |
LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor |
LUC7L2 | LUC7-like 2 (S. cerevisiae) |
MEPCE | methylphosphate capping enzyme |
METTL8 | methyltransferase like 8 |
MSL1 | male-specific lethal 1 homolog (Drosophila) |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
MYD88 | myeloid differentiation primary response 88 |
NCS1 | neuronal calcium sensor 1 |
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
NPY1R | neuropeptide Y receptor Y1 |
NRIP1 | nuclear receptor interacting protein 1 |
NSD1 | nuclear receptor binding SET domain protein 1 |
NUAK1 | NUAK family, SNF1-like kinase, 1 |
PLK2 | polo-like kinase 2 |
POGK | pogo transposable element with KRAB domain |
PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
PRR15L | proline rich 15-like |
RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
SCAF8 | SR-related CTD-associated factor 8 |
SCRN1 | secernin 1 |
SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
SETD1B | SET domain containing 1B |
SFMBT1 | Scm-like with four mbt domains 1 |
SLC35F2 | solute carrier family 35, member F2 |
SMAD7 | SMAD family member 7 |
SNHG20 | small nucleolar RNA host gene 20 |
SNHG3 | small nucleolar RNA host gene 3 |
SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
SRSF4 | serine/arginine-rich splicing factor 4 |
STC2 | stanniocalcin 2 |
TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
TCEAL1 | transcription elongation factor A (SII)-like 1 |
TGIF1 | TGFB-induced factor homeobox 1 |
TRIB3 | tribbles pseudokinase 3 |
TRIM16 | tripartite motif containing 16 |
TRIM8 | tripartite motif containing 8 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
TRPS1 | trichorhinophalangeal syndrome I |
TSKU | tsukushi, small leucine rich proteoglycan |
USP21 | ubiquitin specific peptidase 21 |
VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
VRK2 | vaccinia related kinase 2 |
WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
WDR74 | WD repeat domain 74 |
XBP1 | X-box binding protein 1 |
YAP1 | Yes-associated protein 1 |
ZBED1 | zinc finger, BED-type containing 1 |
ZC3H4 | zinc finger CCCH-type containing 4 |
ZHX2 | zinc fingers and homeoboxes 2 |
ZIC1 | Zic family member 1 |
ZMIZ1 | zinc finger, MIZ-type containing 1 |
ZNF282 | zinc finger protein 282 |
ZNF573 | zinc finger protein 573 |
ZNF692 | zinc finger protein 692 |
ZNHIT2 | zinc finger, HIT-type containing 2 |