Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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200 genes differentially expressed following the trichostatin A-6951 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
ACSF2 | acyl-CoA synthetase family member 2 |
AHNAK2 | AHNAK nucleoprotein 2 |
AKAP12 | A kinase (PRKA) anchor protein 12 |
ALDOC | aldolase C, fructose-bisphosphate |
ARMCX2 | armadillo repeat containing, X-linked 2 |
BAIAP2 | BAI1-associated protein 2 |
BAIAP3 | BAI1-associated protein 3 |
CCDC28A | coiled-coil domain containing 28A |
CCNA1 | cyclin A1 |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CORO1A | coronin, actin binding protein, 1A |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CXADR | coxsackie virus and adenovirus receptor |
CYB5R1 | cytochrome b5 reductase 1 |
CYLD | cylindromatosis (turban tumor syndrome) |
CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 |
CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
DEGS1 | delta(4)-desaturase, sphingolipid 1 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
DPYSL4 | dihydropyrimidinase-like 4 |
EPOR | erythropoietin receptor |
FKBP1B | FK506 binding protein 1B, 12.6 kDa |
FSCN1 | fascin actin-bundling protein 1 |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GEM | GTP binding protein overexpressed in skeletal muscle |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
GLRX | glutaredoxin (thioltransferase) |
GLS | glutaminase |
GRK5 | G protein-coupled receptor kinase 5 |
GSDMB | gasdermin B |
GTF2B | general transcription factor IIB |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HIC2 | hypermethylated in cancer 2 |
HMHA1 | histocompatibility (minor) HA-1 |
HSPA2 | heat shock 70kDa protein 2 |
ISG15 | ISG15 ubiquitin-like modifier |
KIF5C | kinesin family member 5C |
LIMA1 | LIM domain and actin binding 1 |
LYST | lysosomal trafficking regulator |
MAP1A | microtubule-associated protein 1A |
MAP1B | microtubule-associated protein 1B |
MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
MARK4 | MAP/microtubule affinity-regulating kinase 4 |
MLF1 | myeloid leukemia factor 1 |
MMD | monocyte to macrophage differentiation-associated |
MXRA7 | matrix-remodelling associated 7 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
NEU1 | sialidase 1 (lysosomal sialidase) |
NME7 | NME/NM23 family member 7 |
NPC1 | Niemann-Pick disease, type C1 |
NXN | nucleoredoxin |
OPTN | optineurin |
PADI3 | peptidyl arginine deiminase, type III |
PARP16 | poly (ADP-ribose) polymerase family, member 16 |
PCDH9 | protocadherin 9 |
PDE4A | phosphodiesterase 4A, cAMP-specific |
PER1 | period circadian clock 1 |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PRPH | peripherin |
RAB40B | RAB40B, member RAS oncogene family |
RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RGS2 | regulator of G-protein signaling 2 |
RIMS3 | regulating synaptic membrane exocytosis 3 |
RIPK4 | receptor-interacting serine-threonine kinase 4 |
RNF19B | ring finger protein 19B |
RPL3L | ribosomal protein L3-like |
RTN2 | reticulon 2 |
RUNDC3B | RUN domain containing 3B |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SH3GL3 | SH3-domain GRB2-like 3 |
SIRT4 | sirtuin 4 |
SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
SLC25A44 | solute carrier family 25, member 44 |
SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
SOX9 | SRY (sex determining region Y)-box 9 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STON1 | stonin 1 |
SYT11 | synaptotagmin XI |
TMSB15A | thymosin beta 15a |
TUBA4A | tubulin, alpha 4a |
TUFT1 | tuftelin 1 |
TXNIP | thioredoxin interacting protein |
ULBP2 | UL16 binding protein 2 |
VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
WDR19 | WD repeat domain 19 |
WDR47 | WD repeat domain 47 |
ZCCHC24 | zinc finger, CCHC domain containing 24 |
ZDHHC11 | zinc finger, DHHC-type containing 11 |
ZNF10 | zinc finger protein 10 |
ZNF204P | zinc finger protein 204, pseudogene |
Symbol | Name |
---|---|
ACKR3 | atypical chemokine receptor 3 |
ADNP | activity-dependent neuroprotector homeobox |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
AMOTL2 | angiomotin like 2 |
AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
BANP | BTG3 associated nuclear protein |
BCAR3 | breast cancer anti-estrogen resistance 3 |
BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
BRIX1 | BRX1, biogenesis of ribosomes |
C1ORF106 | chromosome 1 open reading frame 106 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CBR3 | carbonyl reductase 3 |
CCND1 | cyclin D1 |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
CISH | cytokine inducible SH2-containing protein |
COA7 | cytochrome c oxidase assembly factor 7 (putative) |
COIL | coilin |
CTCF | CCCTC-binding factor (zinc finger protein) |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
CUL1 | cullin 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EFNA1 | ephrin-A1 |
EGR3 | early growth response 3 |
ELF4 | E74-like factor 4 (ets domain transcription factor) |
ERBB2IP | erbb2 interacting protein |
ESRP2 | epithelial splicing regulatory protein 2 |
FJX1 | four jointed box 1 (Drosophila) |
FOXA1 | forkhead box A1 |
FOXC1 | forkhead box C1 |
FOXD1 | forkhead box D1 |
GABPB1 | GA binding protein transcription factor, beta subunit 1 |
GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
GATA3 | GATA binding protein 3 |
GIN1 | gypsy retrotransposon integrase 1 |
HOXC11 | homeobox C11 |
INHBB | inhibin, beta B |
IRS1 | insulin receptor substrate 1 |
IRX5 | iroquois homeobox 5 |
KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
KEAP1 | kelch-like ECH-associated protein 1 |
KIAA0753 | KIAA0753 |
LAMA5 | laminin, alpha 5 |
LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
LUC7L2 | LUC7-like 2 (S. cerevisiae) |
MCM9 | minichromosome maintenance complex component 9 |
MEPCE | methylphosphate capping enzyme |
METTL8 | methyltransferase like 8 |
MSL1 | male-specific lethal 1 homolog (Drosophila) |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NPY1R | neuropeptide Y receptor Y1 |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
NRIP1 | nuclear receptor interacting protein 1 |
NSD1 | nuclear receptor binding SET domain protein 1 |
NUAK1 | NUAK family, SNF1-like kinase, 1 |
PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
PLK1 | polo-like kinase 1 |
POGK | pogo transposable element with KRAB domain |
POLR3B | polymerase (RNA) III (DNA directed) polypeptide B |
PRR15L | proline rich 15-like |
PRR3 | proline rich 3 |
RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
RBM23 | RNA binding motif protein 23 |
RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
SETD1B | SET domain containing 1B |
SFMBT1 | Scm-like with four mbt domains 1 |
SLC35F2 | solute carrier family 35, member F2 |
SMAD7 | SMAD family member 7 |
SPIN1 | spindlin 1 |
SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
SRSF4 | serine/arginine-rich splicing factor 4 |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
STC2 | stanniocalcin 2 |
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
TCERG1 | transcription elongation regulator 1 |
TGIF1 | TGFB-induced factor homeobox 1 |
TMEM223 | transmembrane protein 223 |
TMEM30B | transmembrane protein 30B |
TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
TRIB3 | tribbles pseudokinase 3 |
TRIM16 | tripartite motif containing 16 |
TRIM8 | tripartite motif containing 8 |
TRPS1 | trichorhinophalangeal syndrome I |
TSKU | tsukushi, small leucine rich proteoglycan |
UBTF | upstream binding transcription factor, RNA polymerase I |
URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
URGCP | upregulator of cell proliferation |
XBP1 | X-box binding protein 1 |
YAP1 | Yes-associated protein 1 |
YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
ZBED5 | zinc finger, BED-type containing 5 |
ZC3H4 | zinc finger CCCH-type containing 4 |
ZHX2 | zinc fingers and homeoboxes 2 |
ZIC1 | Zic family member 1 |
ZMIZ1 | zinc finger, MIZ-type containing 1 |
ZNF692 | zinc finger protein 692 |