Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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200 genes differentially expressed following the trichostatin A-7077 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
ABHD17B | abhydrolase domain containing 17B |
ABHD6 | abhydrolase domain containing 6 |
ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
ADM | adrenomedullin |
ADRB2 | adrenoceptor beta 2, surface |
AGFG2 | ArfGAP with FG repeats 2 |
AIM1L | absent in melanoma 1-like |
AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
ANGPTL4 | angiopoietin-like 4 |
AQP3 | aquaporin 3 (Gill blood group) |
ARG2 | arginase 2 |
ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
ASMTL | acetylserotonin O-methyltransferase-like |
AVPI1 | arginine vasopressin-induced 1 |
BAIAP2 | BAI1-associated protein 2 |
BAMBI | BMP and activin membrane-bound inhibitor |
BEX1 | brain expressed, X-linked 1 |
BIRC3 | baculoviral IAP repeat containing 3 |
BMP6 | bone morphogenetic protein 6 |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CEP112 | centrosomal protein 112kDa |
CFAP69 | cilia and flagella associated protein 69 |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CORO1A | coronin, actin binding protein, 1A |
CPA4 | carboxypeptidase A4 |
CPD | carboxypeptidase D |
CPM | carboxypeptidase M |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CTGF | connective tissue growth factor |
CTH | cystathionine gamma-lyase |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DDIT4 | DNA-damage-inducible transcript 4 |
DENND3 | DENN/MADD domain containing 3 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DUSP1 | dual specificity phosphatase 1 |
DUSP10 | dual specificity phosphatase 10 |
DUSP5 | dual specificity phosphatase 5 |
EFNB2 | ephrin-B2 |
EGR2 | early growth response 2 |
EPHA4 | EPH receptor A4 |
EPPK1 | epiplakin 1 |
FABP4 | fatty acid binding protein 4, adipocyte |
FAM134B | family with sequence similarity 134, member B |
FLRT3 | fibronectin leucine rich transmembrane protein 3 |
GCDH | glutaryl-CoA dehydrogenase |
GEM | GTP binding protein overexpressed in skeletal muscle |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
GLS | glutaminase |
GMCL1 | germ cell-less, spermatogenesis associated 1 |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
GTF2B | general transcription factor IIB |
HBEGF | heparin-binding EGF-like growth factor |
HMOX1 | heme oxygenase 1 |
HOXA1 | homeobox A1 |
IL11 | interleukin 11 |
IL1RAP | interleukin 1 receptor accessory protein |
INSIG1 | insulin induced gene 1 |
IRF6 | interferon regulatory factor 6 |
KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
KIAA0930 | KIAA0930 |
LIFR | leukemia inhibitory factor receptor alpha |
LMCD1 | LIM and cysteine-rich domains 1 |
LPIN1 | lipin 1 |
MERTK | MER proto-oncogene, tyrosine kinase |
MMP1 | matrix metallopeptidase 1 |
MSX2 | msh homeobox 2 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
NEU1 | sialidase 1 (lysosomal sialidase) |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
OASL | 2'-5'-oligoadenylate synthetase-like |
PELI1 | pellino E3 ubiquitin protein ligase 1 |
PER1 | period circadian clock 1 |
PEX1 | peroxisomal biogenesis factor 1 |
PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
RAI2 | retinoic acid induced 2 |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RGS4 | regulator of G-protein signaling 4 |
RHOB | ras homolog family member B |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STC1 | stanniocalcin 1 |
SYT1 | synaptotagmin I |
SYTL2 | synaptotagmin-like 2 |
TJP3 | tight junction protein 3 |
TMEM47 | transmembrane protein 47 |
TRAFD1 | TRAF-type zinc finger domain containing 1 |
TRIM62 | tripartite motif containing 62 |
TUBB2B | tubulin, beta 2B class IIb |
TUFT1 | tuftelin 1 |
ZFP36 | ZFP36 ring finger protein |
ZNF783 | zinc finger family member 783 |
Symbol | Name |
---|---|
ADNP | activity-dependent neuroprotector homeobox |
AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
BCAR3 | breast cancer anti-estrogen resistance 3 |
BCL7A | B-cell CLL/lymphoma 7A |
BMI1 | BMI1 proto-oncogene, polycomb ring finger |
C3ORF18 | chromosome 3 open reading frame 18 |
CASD1 | CAS1 domain containing 1 |
CBR3 | carbonyl reductase 3 |
CENPA | centromere protein A |
CLCF1 | cardiotrophin-like cytokine factor 1 |
CTCF | CCCTC-binding factor (zinc finger protein) |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
CUL1 | cullin 1 |
DCTN4 | dynactin 4 (p62) |
DENND1B | DENN/MADD domain containing 1B |
DEPDC1 | DEP domain containing 1 |
DSN1 | DSN1, MIS12 kinetochore complex component |
DUSP4 | dual specificity phosphatase 4 |
E2F8 | E2F transcription factor 8 |
FADD | Fas (TNFRSF6)-associated via death domain |
FAIM | Fas apoptotic inhibitory molecule |
FAM169A | family with sequence similarity 169, member A |
FAM57A | family with sequence similarity 57, member A |
FJX1 | four jointed box 1 (Drosophila) |
FOSL1 | FOS-like antigen 1 |
FOXA1 | forkhead box A1 |
FST | follistatin |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
H2AFY2 | H2A histone family, member Y2 |
HAS2 | hyaluronan synthase 2 |
HMGA2 | high mobility group AT-hook 2 |
HMGXB4 | HMG box domain containing 4 |
HOOK1 | hook microtubule-tethering protein 1 |
HSPB8 | heat shock 22kDa protein 8 |
IL33 | interleukin 33 |
IL4R | interleukin 4 receptor |
INHBB | inhibin, beta B |
IRS1 | insulin receptor substrate 1 |
KAT6B | K(lysine) acetyltransferase 6B |
KEAP1 | kelch-like ECH-associated protein 1 |
LMNB1 | lamin B1 |
LPAR1 | lysophosphatidic acid receptor 1 |
LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
LUC7L2 | LUC7-like 2 (S. cerevisiae) |
MANSC1 | MANSC domain containing 1 |
MCM9 | minichromosome maintenance complex component 9 |
MEPCE | methylphosphate capping enzyme |
METTL4 | methyltransferase like 4 |
MEX3C | mex-3 RNA binding family member C |
NDC80 | NDC80 kinetochore complex component |
NHEJ1 | nonhomologous end-joining factor 1 |
NRIP1 | nuclear receptor interacting protein 1 |
NSD1 | nuclear receptor binding SET domain protein 1 |
NUP62 | nucleoporin 62kDa |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
PALMD | palmdelphin |
PCNT | pericentrin |
PPAN | peter pan homolog (Drosophila) |
PPAP2B | phosphatidic acid phosphatase type 2B |
PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 |
PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
RBM23 | RNA binding motif protein 23 |
RIN2 | Ras and Rab interactor 2 |
RIPPLY3 | ripply transcriptional repressor 3 |
SCAF8 | SR-related CTD-associated factor 8 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SETD1B | SET domain containing 1B |
SETMAR | SET domain and mariner transposase fusion gene |
SH2D4A | SH2 domain containing 4A |
SIDT1 | SID1 transmembrane family, member 1 |
SIM2 | single-minded family bHLH transcription factor 2 |
SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
SMAGP | small cell adhesion glycoprotein |
SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
SNX5 | sorting nexin 5 |
SPRY2 | sprouty homolog 2 (Drosophila) |
SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
SRSF4 | serine/arginine-rich splicing factor 4 |
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
TARBP2 | TAR (HIV-1) RNA binding protein 2 |
TCERG1 | transcription elongation regulator 1 |
TEX264 | testis expressed 264 |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
TOE1 | target of EGR1, member 1 (nuclear) |
TRIB3 | tribbles pseudokinase 3 |
TRIM8 | tripartite motif containing 8 |
TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
TSSC4 | tumor suppressing subtransferable candidate 4 |
TWF2 | twinfilin actin binding protein 2 |
VEGFC | vascular endothelial growth factor C |
XBP1 | X-box binding protein 1 |
ZBED8 | zinc finger, BED-type containing 8 |
ZBTB44 | zinc finger and BTB domain containing 44 |
ZC3H4 | zinc finger CCCH-type containing 4 |
ZNF165 | zinc finger protein 165 |
ZNF248 | zinc finger protein 248 |
ZNF32 | zinc finger protein 32 |
ZNF692 | zinc finger protein 692 |
ZZZ3 | zinc finger, ZZ-type containing 3 |