| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tridihexethyl-2964 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AREG | amphiregulin |
| ARMC9 | armadillo repeat containing 9 |
| ATP11A | ATPase, class VI, type 11A |
| AXIN1 | axin 1 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BTD | biotinidase |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC28B | coiled-coil domain containing 28B |
| CCDC57 | coiled-coil domain containing 57 |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CEP41 | centrosomal protein 41kDa |
| DAPK3 | death-associated protein kinase 3 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDN | dendrin |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DLG5 | discs, large homolog 5 (Drosophila) |
| DVL1 | dishevelled segment polarity protein 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| EPHB6 | EPH receptor B6 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM13A | family with sequence similarity 13, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FCMR | Fc fragment of IgM receptor |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GPR1 | G protein-coupled receptor 1 |
| GPR153 | G protein-coupled receptor 153 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HIST1H3G | histone cluster 1, H3g |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOXA9 | homeobox A9 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IL11 | interleukin 11 |
| IL1RN | interleukin 1 receptor antagonist |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| ITGB4 | integrin, beta 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL20 | kelch-like family member 20 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MEFV | Mediterranean fever |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MSR1 | macrophage scavenger receptor 1 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NF2 | neurofibromin 2 (merlin) |
| NIPAL2 | NIPA-like domain containing 2 |
| NMT2 | N-myristoyltransferase 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PCDH12 | protocadherin 12 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PI4KB | phosphatidylinositol 4-kinase, catalytic, beta |
| PLCG1 | phospholipase C, gamma 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRMT2IP | PRMT2 interacting protein |
| PRR7 | proline rich 7 (synaptic) |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| PTAFR | platelet-activating factor receptor |
| PTGES2 | prostaglandin E synthase 2 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RAB6A | RAB6A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBPMS | RNA binding protein with multiple splicing |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RRBP1 | ribosome binding protein 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| TRGV5 | T cell receptor gamma variable 5 |
| TRMT61A | tRNA methyltransferase 61A |
| WAPAL | wings apart-like homolog (Drosophila) |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| YIPF4 | Yip1 domain family, member 4 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF345 | zinc finger protein 345 |
| ZNF428 | zinc finger protein 428 |
| ZNF512B | zinc finger protein 512B |
| ZNF79 | zinc finger protein 79 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ACYP2 | acylphosphatase 2, muscle type |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AEN | apoptosis enhancing nuclease |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ALS2CL | ALS2 C-terminal like |
| APOL6 | apolipoprotein L, 6 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C3 | complement component 3 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD320 | CD320 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP97 | centrosomal protein 97kDa |
| CES3 | carboxylesterase 3 |
| CHM | choroideremia (Rab escort protein 1) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLGN | calmegin |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DYSF | dysferlin |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ETV4 | ets variant 4 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM50B | family with sequence similarity 50, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FHL3 | four and a half LIM domains 3 |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FNBP1L | formin binding protein 1-like |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLCE | glucuronic acid epimerase |
| GPR27 | G protein-coupled receptor 27 |
| GRAMD1B | GRAM domain containing 1B |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BO | histone cluster 1, H2bo |
| HS1BP3 | HCLS1 binding protein 3 |
| IFNA14 | interferon, alpha 14 |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| KIAA0319L | KIAA0319-like |
| KPTN | kaptin (actin binding protein) |
| LAGE3 | L antigen family, member 3 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LINS | lines homolog (Drosophila) |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MED9 | mediator complex subunit 9 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MKS1 | Meckel syndrome, type 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PANX1 | pannexin 1 |
| PDLIM1 | PDZ and LIM domain 1 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| PLA2G15 | phospholipase A2, group XV |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POMT1 | protein-O-mannosyltransferase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PROCR | protein C receptor, endothelial |
| PRR14L | proline rich 14-like |
| QSER1 | glutamine and serine rich 1 |
| RETN | resistin |
| RFXAP | regulatory factor X-associated protein |
| RNF122 | ring finger protein 122 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAI | suppressor of cancer cell invasion |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SH2B2 | SH2B adaptor protein 2 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| STBD1 | starch binding domain 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| THEM6 | thioesterase superfamily member 6 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM110 | transmembrane protein 110 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| YIPF3 | Yip1 domain family, member 3 |
| YY2 | YY2 transcription factor |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF701 | zinc finger protein 701 |
| ZNF76 | zinc finger protein 76 |
| ZNF768 | zinc finger protein 768 |
