| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tridihexethyl-5486 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARL4D | ADP-ribosylation factor-like 4D |
| ARTN | artemin |
| BTG2 | BTG family, member 2 |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| CARD8 | caspase recruitment domain family, member 8 |
| CD84 | CD84 molecule |
| CLMN | calmin (calponin-like, transmembrane) |
| CLSTN2 | calsyntenin 2 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DICER1 | dicer 1, ribonuclease type III |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EMC1 | ER membrane protein complex subunit 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| EVI5 | ecotropic viral integration site 5 |
| FADS2 | fatty acid desaturase 2 |
| FAM120C | family with sequence similarity 120C |
| FAM184A | family with sequence similarity 184, member A |
| FGL2 | fibrinogen-like 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FNTB | farnesyltransferase, CAAX box, beta |
| GAMT | guanidinoacetate N-methyltransferase |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GSAP | gamma-secretase activating protein |
| H2AFY | H2A histone family, member Y |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST1H4D | histone cluster 1, H4d |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HOXB2 | homeobox B2 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL5RA | interleukin 5 receptor, alpha |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNIP2 | Kv channel interacting protein 2 |
| LMTK1 | lemur tail kinase 1 |
| LOC157562 | uncharacterized LOC157562 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MEP1B | meprin A, beta |
| MID1 | midline 1 |
| MINK1 | misshapen-like kinase 1 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MTMR8 | myotubularin related protein 8 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCKAP1 | NCK-associated protein 1 |
| NEK1 | NIMA-related kinase 1 |
| NME5 | NME/NM23 family member 5 |
| NPY2R | neuropeptide Y receptor Y2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PLCG1 | phospholipase C, gamma 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRLR | prolactin receptor |
| PRSS53 | protease, serine, 53 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RGSL1 | regulator of G-protein signaling like 1 |
| RHOT2 | ras homolog family member T2 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RUNDC3B | RUN domain containing 3B |
| SAMD4A | sterile alpha motif domain containing 4A |
| SATB2 | SATB homeobox 2 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SIRT3 | sirtuin 3 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SMIM14 | small integral membrane protein 14 |
| STK4 | serine/threonine kinase 4 |
| T | T, brachyury homolog (mouse) |
| TDRD12 | tudor domain containing 12 |
| TGFB2 | transforming growth factor, beta 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TPSG1 | tryptase gamma 1 |
| TRIM23 | tripartite motif containing 23 |
| TRIM38 | tripartite motif containing 38 |
| UNC119 | unc-119 homolog (C. elegans) |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF286A | zinc finger protein 286A |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMC7 | armadillo repeat containing 7 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C5 | complement component 5 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASZ1 | castor zinc finger 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCDC9 | coiled-coil domain containing 9 |
| CD83 | CD83 molecule |
| CENPO | centromere protein O |
| CHKB | choline kinase beta |
| CIDEC | cell death-inducing DFFA-like effector c |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLSPN | claspin |
| COL4A5 | collagen, type IV, alpha 5 |
| CUEDC1 | CUE domain containing 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM186A | family with sequence similarity 186, member A |
| FBXO31 | F-box protein 31 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| HOXC10 | homeobox C10 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIFAP3 | kinesin-associated protein 3 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LHX1 | LIM homeobox 1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LYRM9 | LYR motif containing 9 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MED9 | mediator complex subunit 9 |
| MITF | microphthalmia-associated transcription factor |
| MLYCD | malonyl-CoA decarboxylase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MYO1D | myosin ID |
| MYO1F | myosin IF |
| NPY5R | neuropeptide Y receptor Y5 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OXTR | oxytocin receptor |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PKN1 | protein kinase N1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POPDC3 | popeye domain containing 3 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRSS22 | protease, serine, 22 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RASA2 | RAS p21 protein activator 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCAP | SREBF chaperone |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPIDR | scaffolding protein involved in DNA repair |
| STAG3 | stromal antigen 3 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SUSD4 | sushi domain containing 4 |
| TAOK1 | TAO kinase 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCTN1 | tectonic family member 1 |
| TDRD7 | tudor domain containing 7 |
| THOP1 | thimet oligopeptidase 1 |
| TIGD6 | tigger transposable element derived 6 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM180 | transmembrane protein 180 |
| TOLLIP | toll interacting protein |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| UBQLN4 | ubiquilin 4 |
| UBXN6 | UBX domain protein 6 |
| USB1 | U6 snRNA biogenesis 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR91 | WD repeat domain 91 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF394 | zinc finger protein 394 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
