trifluoperazine-1004 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the trifluoperazine-1004 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX15 arachidonate 15-lipoxygenase
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASB1 ankyrin repeat and SOCS box containing 1
ATF3 activating transcription factor 3
BDKRB2 bradykinin receptor B2
BIRC3 baculoviral IAP repeat containing 3
C16ORF45 chromosome 16 open reading frame 45
CALCOCO1 calcium binding and coiled-coil domain 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC132 coiled-coil domain containing 132
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
CGA glycoprotein hormones, alpha polypeptide
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCN5 chloride channel, voltage-sensitive 5
CLSTN2 calsyntenin 2
CNTN5 contactin 5
CXCR4 chemokine (C-X-C motif) receptor 4
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGR1 early growth response 1
EMP1 epithelial membrane protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45G growth arrest and DNA-damage-inducible, gamma
GEM GTP binding protein overexpressed in skeletal muscle
GOLGA2 golgin A2
HIST1H2BC histone cluster 1, H2bc
HIST1H2BO histone cluster 1, H2bo
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ICAM1 intercellular adhesion molecule 1
IL18 interleukin 18
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB5 integrin, beta 5
JAG1 jagged 1
JUN jun proto-oncogene
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLF2 Kruppel-like factor 2
KLHL24 kelch-like family member 24
KREMEN2 kringle containing transmembrane protein 2
LIF leukemia inhibitory factor
LPIN1 lipin 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC2 leucine rich repeat containing 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MYL10 myosin, light chain 10, regulatory
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NF1 neurofibromin 1
PALM paralemmin
PARVB parvin, beta
PASK PAS domain containing serine/threonine kinase
PDE4A phosphodiesterase 4A, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLAGL1 pleiomorphic adenoma gene-like 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RCAN1 regulator of calcineurin 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RNASE4 ribonuclease, RNase A family, 4
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SAPCD1 suppressor APC domain containing 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIDT2 SID1 transmembrane family, member 2
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SRCAP Snf2-related CREBBP activator protein
TCL1B T-cell leukemia/lymphoma 1B
TJAP1 tight junction associated protein 1 (peripheral)
TNK1 tyrosine kinase, non-receptor, 1
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2
TRIM29 tripartite motif containing 29
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
VIPR2 vasoactive intestinal peptide receptor 2
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZNF350 zinc finger protein 350
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACAD8 acyl-CoA dehydrogenase family, member 8
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BACE1 beta-site APP-cleaving enzyme 1
BAGE B melanoma antigen
BPGM 2,3-bisphosphoglycerate mutase
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF68 chromosome 11 open reading frame 68
C19ORF40 chromosome 19 open reading frame 40
C1ORF115 chromosome 1 open reading frame 115
C6ORF47 chromosome 6 open reading frame 47
CASD1 CAS1 domain containing 1
CBR4 carbonyl reductase 4
CCNL2 cyclin L2
CCNO cyclin O
CEP170B centrosomal protein 170B
CHST10 carbohydrate sulfotransferase 10
CLSPN claspin
CORO1A coronin, actin binding protein, 1A
CRY2 cryptochrome circadian clock 2
CSTA cystatin A (stefin A)
DBR1 debranching RNA lariats 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC6L excision repair cross-complementation group 6-like
ESRP2 epithelial splicing regulatory protein 2
FAM188A family with sequence similarity 188, member A
FANCC Fanconi anemia, complementation group C
FGGY FGGY carbohydrate kinase domain containing
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GALE UDP-galactose-4-epimerase
GFOD1 glucose-fructose oxidoreductase domain containing 1
GHR growth hormone receptor
GPATCH3 G patch domain containing 3
GPN2 GPN-loop GTPase 2
GRAMD4 GRAM domain containing 4
HIST1H2AJ histone cluster 1, H2aj
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD7 potassium channel tetramerization domain containing 7
KLHL12 kelch-like family member 12
LINC00339 long intergenic non-protein coding RNA 339
LOC100287590 uncharacterized LOC100287590
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEH1 melanoma antigen family H1
MANSC1 MANSC domain containing 1
MAPK12 mitogen-activated protein kinase 12
MBOAT2 membrane bound O-acyltransferase domain containing 2
MDM4 MDM4, p53 regulator
METTL2B methyltransferase like 2B
METTL8 methyltransferase like 8
MFF mitochondrial fission factor
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MRPL44 mitochondrial ribosomal protein L44
MTM1 myotubularin 1
MTRF1 mitochondrial translational release factor 1
MUM1 melanoma associated antigen (mutated) 1
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NARFL nuclear prelamin A recognition factor-like
NHLRC2 NHL repeat containing 2
NRGN neurogranin (protein kinase C substrate, RC3)
NUBP2 nucleotide binding protein 2
NUBPL nucleotide binding protein-like
PDZRN3 PDZ domain containing ring finger 3
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PMCH pro-melanin-concentrating hormone
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR15L proline rich 15-like
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PYCRL pyrroline-5-carboxylate reductase-like
PYGB phosphorylase, glycogen; brain
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBL1 retinoblastoma-like 1
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RPAP1 RNA polymerase II associated protein 1
SECISBP2 SECIS binding protein 2
SFT2D2 SFT2 domain containing 2
SH2B3 SH2B adaptor protein 3
SHARPIN SHANK-associated RH domain interactor
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SNHG3 small nucleolar RNA host gene 3
SYCP2 synaptonemal complex protein 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TEX264 testis expressed 264
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM110 transmembrane protein 110
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TUBGCP5 tubulin, gamma complex associated protein 5
ZBTB3 zinc finger and BTB domain containing 3
ZFP69B ZFP69 zinc finger protein B
ZMYM1 zinc finger, MYM-type 1
ZNF107 zinc finger protein 107
ZNF14 zinc finger protein 14
ZNF586 zinc finger protein 586
ZNF721 zinc finger protein 721
ZNF770 zinc finger protein 770
ZSCAN5A zinc finger and SCAN domain containing 5A