trifluoperazine-1165 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trifluoperazine-1165 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
AKAP7 A kinase (PRKA) anchor protein 7
AQP1 aquaporin 1 (Colton blood group)
ARF6 ADP-ribosylation factor 6
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARNT aryl hydrocarbon receptor nuclear translocator
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG10 autophagy related 10
ATG3 autophagy related 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BBS9 Bardet-Biedl syndrome 9
C17ORF53 chromosome 17 open reading frame 53
C18ORF25 chromosome 18 open reading frame 25
CCL4 chemokine (C-C motif) ligand 4
CCSER2 coiled-coil serine-rich protein 2
CD244 CD244 molecule, natural killer cell receptor 2B4
CDO1 cysteine dioxygenase type 1
CLCN5 chloride channel, voltage-sensitive 5
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CTH cystathionine gamma-lyase
CXCL10 chemokine (C-X-C motif) ligand 10
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAL4 dynein, axonemal, light chain 4
DTNA dystrobrevin, alpha
DZIP3 DAZ interacting zinc finger protein 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FASTK Fas-activated serine/threonine kinase
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCHO1 FCH domain only 1
FCMR Fc fragment of IgM receptor
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
HIST1H2AC histone cluster 1, H2ac
HIST2H2BE histone cluster 2, H2be
IDS iduronate 2-sulfatase
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL24 interleukin 24
JAK3 Janus kinase 3
JUND jun D proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0753 KIAA0753
KLF6 Kruppel-like factor 6
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00115 long intergenic non-protein coding RNA 115
LPIN2 lipin 2
LPPR2 lipid phosphate phosphatase-related protein type 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MARC1 mitochondrial amidoxime reducing component 1
MAX MYC associated factor X
MCM9 minichromosome maintenance complex component 9
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MST1 macrophage stimulating 1
NCOA1 nuclear receptor coactivator 1
NEK3 NIMA-related kinase 3
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NPDC1 neural proliferation, differentiation and control, 1
NTSR1 neurotensin receptor 1 (high affinity)
PGM3 phosphoglucomutase 3
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLK4 polo-like kinase 4
PRDM1 PR domain containing 1, with ZNF domain
PSEN1 presenilin 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PWAR5 Prader Willi/Angelman region RNA 5
PYGB phosphorylase, glycogen; brain
QPCT glutaminyl-peptide cyclotransferase
RAB28 RAB28, member RAS oncogene family
RBPMS RNA binding protein with multiple splicing
RCAN1 regulator of calcineurin 1
RGS10 regulator of G-protein signaling 10
RIPK2 receptor-interacting serine-threonine kinase 2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RWDD2A RWD domain containing 2A
SCARB2 scavenger receptor class B, member 2
SENP6 SUMO1/sentrin specific peptidase 6
SGMS1 sphingomyelin synthase 1
SPP1 secreted phosphoprotein 1
STK19 serine/threonine kinase 19
STK3 serine/threonine kinase 3
STX7 syntaxin 7
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TEC tec protein tyrosine kinase
TEP1 telomerase-associated protein 1
TPD52 tumor protein D52
TRAF1 TNF receptor-associated factor 1
TRIM25 tripartite motif containing 25
TTLL5 tubulin tyrosine ligase-like family member 5
UGCG UDP-glucose ceramide glucosyltransferase
WDR33 WD repeat domain 33
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF155 zinc finger protein 155
ZNF235 zinc finger protein 235
ZNF75D zinc finger protein 75D
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADGRA3 adhesion G protein-coupled receptor A3
ADM adrenomedullin
AKT1 v-akt murine thymoma viral oncogene homolog 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B3GNT1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCCIP BRCA2 and CDKN1A interacting protein
BRMS1 breast cancer metastasis suppressor 1
C17ORF70 chromosome 17 open reading frame 70
C1ORF35 chromosome 1 open reading frame 35
C6ORF47 chromosome 6 open reading frame 47
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CHMP1A charged multivesicular body protein 1A
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DUSP2 dual specificity phosphatase 2
ECHDC2 enoyl CoA hydratase domain containing 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFHD2 EF-hand domain family, member D2
ENDOG endonuclease G
FAM127A family with sequence similarity 127, member A
FAM50B family with sequence similarity 50, member B
FHOD1 formin homology 2 domain containing 1
FMNL1 formin-like 1
FOXN2 forkhead box N2
GAB2 GRB2-associated binding protein 2
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GNL1 guanine nucleotide binding protein-like 1
GPR22 G protein-coupled receptor 22
HPS6 Hermansky-Pudlak syndrome 6
HRAS Harvey rat sarcoma viral oncogene homolog
IDI2-AS1 IDI2 antisense RNA 1
IL4R interleukin 4 receptor
ITPKB inositol-trisphosphate 3-kinase B
JUNB jun B proto-oncogene
KIAA0556 KIAA0556
KIF13B kinesin family member 13B
LAS1L LAS1-like (S. cerevisiae)
LMNB1 lamin B1
LRP3 low density lipoprotein receptor-related protein 3
LRRK1 leucine-rich repeat kinase 1
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
METTL8 methyltransferase like 8
MRPL44 mitochondrial ribosomal protein L44
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUM1 melanoma associated antigen (mutated) 1
NABP2 nucleic acid binding protein 2
NINJ1 ninjurin 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NT5M 5',3'-nucleotidase, mitochondrial
PAK1IP1 PAK1 interacting protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PNPLA6 patatin-like phospholipase domain containing 6
PRKCZ protein kinase C, zeta
PTDSS2 phosphatidylserine synthase 2
PTOV1 prostate tumor overexpressed 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QTRT1 queuine tRNA-ribosyltransferase 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SALL2 spalt-like transcription factor 2
SIRT6 sirtuin 6
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMAD7 SMAD family member 7
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STIM1 stromal interaction molecule 1
STK25 serine/threonine kinase 25
TERT telomerase reverse transcriptase
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMOD3 tropomodulin 3 (ubiquitous)
TPCN1 two pore segment channel 1
TSSC1 tumor suppressing subtransferable candidate 1
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
UBE2O ubiquitin-conjugating enzyme E2O
UBIAD1 UbiA prenyltransferase domain containing 1
UNG uracil-DNA glycosylase
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XPC xeroderma pigmentosum, complementation group C
XYLT2 xylosyltransferase II
ZBED1 zinc finger, BED-type containing 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF32 zinc finger protein 32
ZNF510 zinc finger protein 510
ZNF528 zinc finger protein 528
ZNF611 zinc finger protein 611