| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the trifluoperazine-5221 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADRA1D | adrenoceptor alpha 1D |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BBC3 | BCL2 binding component 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CARD10 | caspase recruitment domain family, member 10 |
| CCNG2 | cyclin G2 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CGA | glycoprotein hormones, alpha polypeptide |
| CUL7 | cullin 7 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DUSP4 | dual specificity phosphatase 4 |
| ECE1 | endothelin converting enzyme 1 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| FAM174B | family with sequence similarity 174, member B |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FST | follistatin |
| GAP43 | growth associated protein 43 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLRX | glutaredoxin (thioltransferase) |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIST1H1D | histone cluster 1, H1d |
| HMOX1 | heme oxygenase 1 |
| HOXB6 | homeobox B6 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL27RA | interleukin 27 receptor, alpha |
| IL6 | interleukin 6 |
| INHBE | inhibin, beta E |
| IRF9 | interferon regulatory factor 9 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| KIF3C | kinesin family member 3C |
| KLHL24 | kelch-like family member 24 |
| KLHL25 | kelch-like family member 25 |
| LIF | leukemia inhibitory factor |
| LMO4 | LIM domain only 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MEP1B | meprin A, beta |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MXD4 | MAX dimerization protein 4 |
| NDRG1 | N-myc downstream regulated 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOVA2 | neuro-oncological ventral antigen 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PGR | progesterone receptor |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLAU | plasminogen activator, urokinase |
| PLIN2 | perilipin 2 |
| PON1 | paraoxonase 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTHLH | parathyroid hormone-like hormone |
| PVALB | parvalbumin |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| S100A13 | S100 calcium binding protein A13 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SAMD9 | sterile alpha motif domain containing 9 |
| SDC3 | syndecan 3 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPAG8 | sperm associated antigen 8 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TLR2 | toll-like receptor 2 |
| TNPO2 | transportin 2 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM2 | tripartite motif containing 2 |
| YY2 | YY2 transcription factor |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADORA2B | adenosine A2b receptor |
| AGK | acylglycerol kinase |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BMP4 | bone morphogenetic protein 4 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC121 | coiled-coil domain containing 121 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFAP44 | cilia and flagella associated protein 44 |
| CLDN15 | claudin 15 |
| CLDN9 | claudin 9 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERCC8 | excision repair cross-complementation group 8 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EXOC5 | exocyst complex component 5 |
| FAM155B | family with sequence similarity 155, member B |
| FAM204A | family with sequence similarity 204, member A |
| FBXO22 | F-box protein 22 |
| FKBP5 | FK506 binding protein 5 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GALK1 | galactokinase 1 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GAMT | guanidinoacetate N-methyltransferase |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLMN | glomulin, FKBP associated protein |
| GLUD2 | glutamate dehydrogenase 2 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR27 | G protein-coupled receptor 27 |
| HIST1H4F | histone cluster 1, H4f |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IGFLR1 | IGF-like family receptor 1 |
| IL17RA | interleukin 17 receptor A |
| IL22 | interleukin 22 |
| IL4R | interleukin 4 receptor |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LIN7A | lin-7 homolog A (C. elegans) |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NOL12 | nucleolar protein 12 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PP14571 | uncharacterized LOC100130449 |
| PRR15L | proline rich 15-like |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB23 | RAB23, member RAS oncogene family |
| RAB5C | RAB5C, member RAS oncogene family |
| RGS19 | regulator of G-protein signaling 19 |
| RNF25 | ring finger protein 25 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| S100A7 | S100 calcium binding protein A7 |
| SCHIP1 | schwannomin interacting protein 1 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STRA6 | stimulated by retinoic acid 6 |
| STRN | striatin, calmodulin binding protein |
| TMEM168 | transmembrane protein 168 |
| TRAIP | TRAF interacting protein |
| TRIM45 | tripartite motif containing 45 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TWISTNB | TWIST neighbor |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| WDR4 | WD repeat domain 4 |
| WDR7 | WD repeat domain 7 |
| ZNF239 | zinc finger protein 239 |
| ZNF692 | zinc finger protein 692 |
