| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the trifluoperazine-910 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOE | apolipoprotein E |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BST1 | bone marrow stromal cell antigen 1 |
| CCNG2 | cyclin G2 |
| CD58 | CD58 molecule |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CGA | glycoprotein hormones, alpha polypeptide |
| COL1A1 | collagen, type I, alpha 1 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTSZ | cathepsin Z |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYHR1 | cysteine/histidine-rich 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| FADS3 | fatty acid desaturase 3 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FHL1 | four and a half LIM domains 1 |
| FNDC3A | fibronectin type III domain containing 3A |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXJ3 | forkhead box J3 |
| GAMT | guanidinoacetate N-methyltransferase |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GRB7 | growth factor receptor-bound protein 7 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HDAC5 | histone deacetylase 5 |
| HIST1H3B | histone cluster 1, H3b |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| IL1R1 | interleukin 1 receptor, type I |
| INADL | InaD-like (Drosophila) |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| JUN | jun proto-oncogene |
| KIZ | kizuna centrosomal protein |
| KLHL24 | kelch-like family member 24 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LHX6 | LIM homeobox 6 |
| LPIN1 | lipin 1 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1B | microtubule-associated protein 1B |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBTD1 | mbt domain containing 1 |
| MIR622 | microRNA 622 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MVK | mevalonate kinase |
| MXD4 | MAX dimerization protein 4 |
| NDRG1 | N-myc downstream regulated 1 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NKX3-2 | NK3 homeobox 2 |
| NRP2 | neuropilin 2 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLA2G3 | phospholipase A2, group III |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RND1 | Rho family GTPase 1 |
| RRBP1 | ribosome binding protein 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPATA1 | spermatogenesis associated 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRCAP | Snf2-related CREBBP activator protein |
| ST20 | suppressor of tumorigenicity 20 |
| SUGP1 | SURP and G patch domain containing 1 |
| THBS3 | thrombospondin 3 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM259 | transmembrane protein 259 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TREX1 | three prime repair exonuclease 1 |
| TRIM2 | tripartite motif containing 2 |
| TRIM23 | tripartite motif containing 23 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 |
| ZNF350 | zinc finger protein 350 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| APIP | APAF1 interacting protein |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BBC3 | BCL2 binding component 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC25 | coiled-coil domain containing 25 |
| CCNE2 | cyclin E2 |
| CCNO | cyclin O |
| CDK8 | cyclin-dependent kinase 8 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPO | centromere protein O |
| CEP72 | centrosomal protein 72kDa |
| CEP97 | centrosomal protein 97kDa |
| DBR1 | debranching RNA lariats 1 |
| DEAF1 | DEAF1 transcription factor |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| EEA1 | early endosome antigen 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FAM155B | family with sequence similarity 155, member B |
| FOXC1 | forkhead box C1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GPALPP1 | GPALPP motifs containing 1 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HIRA | histone cell cycle regulator |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC10 | homeobox C10 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFT22 | intraflagellar transport 22 |
| IPP | intracisternal A particle-promoted polypeptide |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIN7B | lin-7 homolog B (C. elegans) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC100287590 | uncharacterized LOC100287590 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAP9 | microtubule-associated protein 9 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MEIS1 | Meis homeobox 1 |
| MFAP2 | microfibrillar-associated protein 2 |
| MMP9 | matrix metallopeptidase 9 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MT1HL1 | metallothionein 1H-like 1 |
| MYNN | myoneurin |
| NAG18 | NAG18 mRNA |
| NLRX1 | NLR family member X1 |
| NUPL2 | nucleoporin like 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCBP4 | poly(rC) binding protein 4 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PTK6 | protein tyrosine kinase 6 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBL1 | retinoblastoma-like 1 |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNMTL1 | RNA methyltransferase like 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCAP | SREBF chaperone |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC35F6 | solute carrier family 35, member F6 |
| SNX10 | sorting nexin 10 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM168 | transmembrane protein 168 |
| TMEM183A | transmembrane protein 183A |
| TMEM38B | transmembrane protein 38B |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TUBA4A | tubulin, alpha 4a |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| USB1 | U6 snRNA biogenesis 1 |
| WDR60 | WD repeat domain 60 |
| WDR76 | WD repeat domain 76 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF212 | zinc finger protein 212 |
| ZNF254 | zinc finger protein 254 |
| ZNF35 | zinc finger protein 35 |
| ZNF668 | zinc finger protein 668 |
| ZNF85 | zinc finger protein 85 |
| ZW10 | zw10 kinetochore protein |