triflupromazine-1691 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the triflupromazine-1691 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ABLIM3 actin binding LIM protein family, member 3
ACVR1B activin A receptor, type IB
AKAP7 A kinase (PRKA) anchor protein 7
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARL4C ADP-ribosylation factor-like 4C
ARTN artemin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATAT1 alpha tubulin acetyltransferase 1
ATF3 activating transcription factor 3
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BIK BCL2-interacting killer (apoptosis-inducing)
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC132 coiled-coil domain containing 132
CDC25A cell division cycle 25A
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
COL1A1 collagen, type I, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CTIF CBP80/20-dependent translation initiation factor
DGAT1 diacylglycerol O-acyltransferase 1
FBXO11 F-box protein 11
FLOT1 flotillin 1
GLRX3 glutaredoxin 3
GOSR2 golgi SNAP receptor complex member 2
GPR137 G protein-coupled receptor 137
GPR182 G protein-coupled receptor 182
GRB10 growth factor receptor-bound protein 10
GSTM4 glutathione S-transferase mu 4
HAP1 huntingtin-associated protein 1
HNMT histamine N-methyltransferase
ICA1 islet cell autoantigen 1, 69kDa
IDS iduronate 2-sulfatase
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL17RA interleukin 17 receptor A
JAKMIP2 janus kinase and microtubule interacting protein 2
JUND jun D proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD7 potassium channel tetramerization domain containing 7
KRI1 KRI1 homolog (S. cerevisiae)
LONP2 lon peptidase 2, peroxisomal
MED25 mediator complex subunit 25
MTA1 metastasis associated 1
MTCP1 mature T-cell proliferation 1
NCAPH2 non-SMC condensin II complex, subunit H2
NEK2 NIMA-related kinase 2
NFX1 nuclear transcription factor, X-box binding 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUMA1 nuclear mitotic apparatus protein 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB13 protocadherin beta 13
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PEX26 peroxisomal biogenesis factor 26
PIDD1 p53-induced death domain protein 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAGL1 pleiomorphic adenoma gene-like 1
PLK4 polo-like kinase 4
PML promyelocytic leukemia
POU2F2 POU class 2 homeobox 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PSG9 pregnancy specific beta-1-glycoprotein 9
PTRF polymerase I and transcript release factor
PVRL3 poliovirus receptor-related 3
PYCRL pyrroline-5-carboxylate reductase-like
RAB28 RAB28, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RANBP3 RAN binding protein 3
RGS17 regulator of G-protein signaling 17
RGS19 regulator of G-protein signaling 19
RHBDD3 rhomboid domain containing 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL13P5 ribosomal protein L13 pseudogene 5
RPS14 ribosomal protein S14
SAFB2 scaffold attachment factor B2
SAYSD1 SAYSVFN motif domain containing 1
SIX2 SIX homeobox 2
SNAI2 snail family zinc finger 2
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPTBN1 spectrin, beta, non-erythrocytic 1
STX7 syntaxin 7
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAGLN3 transgelin 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THEM6 thioesterase superfamily member 6
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPR translocated promoter region, nuclear basket protein
TRIM2 tripartite motif containing 2
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
ZCCHC24 zinc finger, CCHC domain containing 24
ZFPL1 zinc finger protein-like 1
ZNF227 zinc finger protein 227
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSS3 acyl-CoA synthetase short-chain family member 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRE5 adhesion G protein-coupled receptor E5
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMPD2 adenosine monophosphate deaminase 2
ANXA2P3 annexin A2 pseudogene 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOD apolipoprotein D
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATF7IP2 activating transcription factor 7 interacting protein 2
BCORL1 BCL6 corepressor-like 1
C14ORF132 chromosome 14 open reading frame 132
C4ORF29 chromosome 4 open reading frame 29
C5 complement component 5
CA11 carbonic anhydrase XI
CAPRIN2 caprin family member 2
CARD8 caspase recruitment domain family, member 8
CCNT1 cyclin T1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHPF chondroitin polymerizing factor
CIDEC cell death-inducing DFFA-like effector c
CLCF1 cardiotrophin-like cytokine factor 1
CLCN5 chloride channel, voltage-sensitive 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CSTA cystatin A (stefin A)
CTAGE5 CTAGE family, member 5
CUEDC1 CUE domain containing 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DACH1 dachshund family transcription factor 1
DCP1A decapping mRNA 1A
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
ELP3 elongator acetyltransferase complex subunit 3
EPHA4 EPH receptor A4
FAM114A2 family with sequence similarity 114, member A2
FBRS fibrosin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FER fer (fps/fes related) tyrosine kinase
GBP2 guanylate binding protein 2, interferon-inducible
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNL1 guanine nucleotide binding protein-like 1
GRB7 growth factor receptor-bound protein 7
GSTA4 glutathione S-transferase alpha 4
GUSBP3 glucuronidase, beta pseudogene 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2BI histone cluster 1, H2bi
HPSE heparanase
IDI2-AS1 IDI2 antisense RNA 1
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
KLHL36 kelch-like family member 36
LAS1L LAS1-like (S. cerevisiae)
LGMN legumain
LRP3 low density lipoprotein receptor-related protein 3
MAP9 microtubule-associated protein 9
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
METTL2B methyltransferase like 2B
METTL8 methyltransferase like 8
MNX1 motor neuron and pancreas homeobox 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NDRG1 N-myc downstream regulated 1
NPFFR1 neuropeptide FF receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
PTPN9 protein tyrosine phosphatase, non-receptor type 9
QTRT1 queuine tRNA-ribosyltransferase 1
RAB4B RAB4B, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RNF170 ring finger protein 170
RNF31 ring finger protein 31
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A9 solute carrier family 12, member 9
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPIDR scaffolding protein involved in DNA repair
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TBX19 T-box 19
TCTA T-cell leukemia translocation altered
THRAP3 thyroid hormone receptor associated protein 3
TMEM57 transmembrane protein 57
TMEM62 transmembrane protein 62
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TWSG1 twisted gastrulation BMP signaling modulator 1
UNC119 unc-119 homolog (C. elegans)
WDR91 WD repeat domain 91
WRN Werner syndrome, RecQ helicase-like
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZMAT5 zinc finger, matrin-type 5
ZNF205 zinc finger protein 205
ZNF211 zinc finger protein 211