triflupromazine-1813 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the triflupromazine-1813 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANKRD12 ankyrin repeat domain 12
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARTN artemin
C17ORF80 chromosome 17 open reading frame 80
CALD1 caldesmon 1
CCNT2 cyclin T2
CDC5L cell division cycle 5-like
CDV3 CDV3 homolog (mouse)
CFLAR CASP8 and FADD-like apoptosis regulator
COL6A1 collagen, type VI, alpha 1
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUX1 cut-like homeobox 1
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
CYB561 cytochrome b561
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DENND2A DENN/MADD domain containing 2A
DPF3 D4, zinc and double PHD fingers, family 3
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EIF1 eukaryotic translation initiation factor 1
EVI5 ecotropic viral integration site 5
FANCF Fanconi anemia, complementation group F
FCF1 FCF1 rRNA-processing protein
FCHSD2 FCH and double SH3 domains 2
FGF5 fibroblast growth factor 5
FLOT1 flotillin 1
FSCN1 fascin actin-bundling protein 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GEMIN4 gem (nuclear organelle) associated protein 4
GRAMD3 GRAM domain containing 3
GUSBP3 glucuronidase, beta pseudogene 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H4C histone cluster 1, H4c
HOMER2 homer scaffolding protein 2
HSPA4 heat shock 70kDa protein 4
INCENP inner centromere protein antigens 135/155kDa
ING4 inhibitor of growth family, member 4
ITGB4 integrin, beta 4
KCTD20 potassium channel tetramerization domain containing 20
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMAN1 lectin, mannose-binding, 1
LPIN2 lipin 2
LRRK1 leucine-rich repeat kinase 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MATN3 matrilin 3
MAX MYC associated factor X
MBTD1 mbt domain containing 1
MET MET proto-oncogene, receptor tyrosine kinase
MPDZ multiple PDZ domain protein
MT1HL1 metallothionein 1H-like 1
MTAP methylthioadenosine phosphorylase
MXD4 MAX dimerization protein 4
NNT nicotinamide nucleotide transhydrogenase
PAK1IP1 PAK1 interacting protein 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAPOLA poly(A) polymerase alpha
PASK PAS domain containing serine/threonine kinase
PDE4DIP phosphodiesterase 4D interacting protein
PDGFA platelet-derived growth factor alpha polypeptide
PHC2 polyhomeotic homolog 2 (Drosophila)
PICALM phosphatidylinositol binding clathrin assembly protein
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PPP6R2 protein phosphatase 6, regulatory subunit 2
PVR poliovirus receptor
RARS arginyl-tRNA synthetase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS19 regulator of G-protein signaling 19
RNASEH2B ribonuclease H2, subunit B
RPL35A ribosomal protein L35a
RRBP1 ribosome binding protein 1
RREB1 ras responsive element binding protein 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SS18 synovial sarcoma translocation, chromosome 18
STK17B serine/threonine kinase 17b
SUGP1 SURP and G patch domain containing 1
TBCD tubulin folding cofactor D
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM47 transmembrane protein 47
TMPO thymopoietin
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TUBA3C tubulin, alpha 3c
UGCG UDP-glucose ceramide glucosyltransferase
UTRN utrophin
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ALG12 ALG12, alpha-1,6-mannosyltransferase
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID4A AT rich interactive domain 4A (RBP1-like)
ARMC6 armadillo repeat containing 6
ATP13A2 ATPase type 13A2
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1R complement component 1, r subcomponent
C7ORF43 chromosome 7 open reading frame 43
CCDC176 coiled-coil domain containing 176
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COG4 component of oligomeric golgi complex 4
CPA4 carboxypeptidase A4
CST4 cystatin S
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DNMBP dynamin binding protein
DTWD1 DTW domain containing 1
EPPK1 epiplakin 1
FAM160B2 family with sequence similarity 160, member B2
FBRS fibrosin
FBXL7 F-box and leucine-rich repeat protein 7
FKBP10 FK506 binding protein 10, 65 kDa
GPR1 G protein-coupled receptor 1
HDAC7 histone deacetylase 7
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2BC histone cluster 1, H2bc
HOXA1 homeobox A1
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL17RA interleukin 17 receptor A
INF2 inverted formin, FH2 and WH2 domain containing
IRAK4 interleukin-1 receptor-associated kinase 4
ITPKC inositol-trisphosphate 3-kinase C
KCTD15 potassium channel tetramerization domain containing 15
KLC2 kinesin light chain 2
LIMS2 LIM and senescent cell antigen-like domains 2
LZTR1 leucine-zipper-like transcription regulator 1
MACROD1 MACRO domain containing 1
MANSC1 MANSC domain containing 1
MAP9 microtubule-associated protein 9
MAST3 microtubule associated serine/threonine kinase 3
MED9 mediator complex subunit 9
METTL22 methyltransferase like 22
MGC12488
MRPL52 mitochondrial ribosomal protein L52
MXRA8 matrix-remodelling associated 8
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NPM3 nucleophosmin/nucleoplasmin 3
NSD1 nuclear receptor binding SET domain protein 1
NSUN3 NOP2/Sun domain family, member 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUP62CL nucleoporin 62kDa C-terminal like
OGFRL1 opioid growth factor receptor-like 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP16 poly (ADP-ribose) polymerase family, member 16
PCOLCE procollagen C-endopeptidase enhancer
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PILRB paired immunoglobin-like type 2 receptor beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLH polymerase (DNA directed), eta
PPP1R13B protein phosphatase 1, regulatory subunit 13B
RAB23 RAB23, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBL1 retinoblastoma-like 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIN1 Ras and Rab interactor 1
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RNF31 ring finger protein 31
SALL2 spalt-like transcription factor 2
SAMD9 sterile alpha motif domain containing 9
SCML2 sex comb on midleg-like 2 (Drosophila)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPAG7 sperm associated antigen 7
SPATA2L spermatogenesis associated 2-like
STIM1 stromal interaction molecule 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBX19 T-box 19
TESK2 testis-specific kinase 2
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRABD TraB domain containing
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TSKU tsukushi, small leucine rich proteoglycan
USB1 U6 snRNA biogenesis 1
VASP vasodilator-stimulated phosphoprotein
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZMAT5 zinc finger, matrin-type 5
ZNF250 zinc finger protein 250
ZNF32 zinc finger protein 32
ZNF324 zinc finger protein 324
ZNF385D zinc finger protein 385D
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862