triflupromazine-1855 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the triflupromazine-1855 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ADAP1 ArfGAP with dual PH domains 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ARMC8 armadillo repeat containing 8
ARRB1 arrestin, beta 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BHLHE41 basic helix-loop-helix family, member e41
BMP7 bone morphogenetic protein 7
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CDCP1 CUB domain containing protein 1
CDK3 cyclin-dependent kinase 3
CES3 carboxylesterase 3
CLEC3B C-type lectin domain family 3, member B
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CORO2A coronin, actin binding protein, 2A
CPTP ceramide-1-phosphate transfer protein
DAPK1 death-associated protein kinase 1
DCTN1 dynactin 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DLX2 distal-less homeobox 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOK3 docking protein 3
DSTYK dual serine/threonine and tyrosine protein kinase
DZIP1 DAZ interacting zinc finger protein 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EXOSC7 exosome component 7
FAM3A family with sequence similarity 3, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCMR Fc fragment of IgM receptor
FKBP5 FK506 binding protein 5
FRY furry homolog (Drosophila)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRWD1 glutamate-rich WD repeat containing 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HDAC7 histone deacetylase 7
HEMK1 HemK methyltransferase family member 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
ICA1 islet cell autoantigen 1, 69kDa
ING1 inhibitor of growth family, member 1
JAG2 jagged 2
KLK1 kallikrein 1
KMT2A lysine (K)-specific methyltransferase 2A
KRIT1 KRIT1, ankyrin repeat containing
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LINC00115 long intergenic non-protein coding RNA 115
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MRPL34 mitochondrial ribosomal protein L34
MYBPH myosin binding protein H
NEFH neurofilament, heavy polypeptide
NEK9 NIMA-related kinase 9
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUP160 nucleoporin 160kDa
OVGP1 oviductal glycoprotein 1, 120kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PEX26 peroxisomal biogenesis factor 26
PFN1 profilin 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PNPLA4 patatin-like phospholipase domain containing 4
PORCN porcupine homolog (Drosophila)
PPP4R4 protein phosphatase 4, regulatory subunit 4
PPP5C protein phosphatase 5, catalytic subunit
PRMT7 protein arginine methyltransferase 7
PSKH1 protein serine kinase H1
QTRT1 queuine tRNA-ribosyltransferase 1
RECQL4 RecQ protein-like 4
RGS10 regulator of G-protein signaling 10
RPL35A ribosomal protein L35a
RPS2 ribosomal protein S2
SETD6 SET domain containing 6
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC22A18 solute carrier family 22, member 18
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SRCAP Snf2-related CREBBP activator protein
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STOM stomatin
SUGP1 SURP and G patch domain containing 1
TBC1D30 TBC1 domain family, member 30
TBC1D4 TBC1 domain family, member 4
TMEM70 transmembrane protein 70
TPP1 tripeptidyl peptidase I
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN2 tetraspanin 2
UBOX5 U-box domain containing 5
USF2 upstream transcription factor 2, c-fos interacting
WDR6 WD repeat domain 6
ZEB1 zinc finger E-box binding homeobox 1
ZNF324 zinc finger protein 324
ZNF778 zinc finger protein 778
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGO4 argonaute RISC catalytic component 4
ALG9 ALG9, alpha-1,2-mannosyltransferase
ANKRD40 ankyrin repeat domain 40
APH1A APH1A gamma secretase subunit
APOLD1 apolipoprotein L domain containing 1
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARHGAP12 Rho GTPase activating protein 12
ARMC7 armadillo repeat containing 7
ASTE1 asteroid homolog 1 (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
BAX BCL2-associated X protein
CCDC130 coiled-coil domain containing 130
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST10 carbohydrate sulfotransferase 10
CPNE7 copine VII
CXORF56 chromosome X open reading frame 56
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DYNLT1 dynein, light chain, Tctex-type 1
ECM1 extracellular matrix protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM184A family with sequence similarity 184, member A
FAM204A family with sequence similarity 204, member A
FAM53B family with sequence similarity 53, member B
FANCF Fanconi anemia, complementation group F
FBXO3 F-box protein 3
FKBP14 FK506 binding protein 14, 22 kDa
GIPC1 GIPC PDZ domain containing family, member 1
GYS1 glycogen synthase 1 (muscle)
HIST1H2BI histone cluster 1, H2bi
HPS6 Hermansky-Pudlak syndrome 6
HPSE heparanase
IRAK4 interleukin-1 receptor-associated kinase 4
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM7A lysine (K)-specific demethylase 7A
KIFC1 kinesin family member C1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIG1 ligase I, DNA, ATP-dependent
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
LXN latexin
MANEA mannosidase, endo-alpha
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MLF2 myeloid leukemia factor 2
MT1HL1 metallothionein 1H-like 1
MTERF4 mitochondrial transcription termination factor 4
MYO1E myosin IE
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NME7 NME/NM23 family member 7
NRBP1 nuclear receptor binding protein 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLAG1 pleiomorphic adenoma gene 1
PNMA1 paraneoplastic Ma antigen 1
PNOC prepronociceptin
POR P450 (cytochrome) oxidoreductase
PRR4 proline rich 4 (lacrimal)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF121 ring finger protein 121
RNF141 ring finger protein 141
RNF146 ring finger protein 146
RNF2 ring finger protein 2
RPGR retinitis pigmentosa GTPase regulator
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNHG20 small nucleolar RNA host gene 20
SNORA21 small nucleolar RNA, H/ACA box 21
SNRPN small nuclear ribonucleoprotein polypeptide N
STARD8 StAR-related lipid transfer (START) domain containing 8
STEAP3 STEAP family member 3, metalloreductase
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBCCD1 TBCC domain containing 1
THOC6 THO complex 6
TM6SF1 transmembrane 6 superfamily member 1
TMEM254 transmembrane protein 254
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNNT1 troponin T type 1 (skeletal, slow)
TNRC6B trinucleotide repeat containing 6B
TOM1L1 target of myb1 (chicken)-like 1
TXLNG taxilin gamma
UNC119 unc-119 homolog (C. elegans)
URM1 ubiquitin related modifier 1
USP19 ubiquitin specific peptidase 19
VIM vimentin
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WSB2 WD repeat and SOCS box containing 2
WT1-AS WT1 antisense RNA
XPC xeroderma pigmentosum, complementation group C
ZBED8 zinc finger, BED-type containing 8
ZNF10 zinc finger protein 10
ZNF175 zinc finger protein 175
ZNF33B zinc finger protein 33B
ZNF672 zinc finger protein 672
ZNRD1-AS1 ZNRD1 antisense RNA 1