| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the trifluridine-5819 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| AHI1 | Abelson helper integration site 1 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BTG3 | BTG family, member 3 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CCNE2 | cyclin E2 |
| CD80 | CD80 molecule |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CHD7 | chromodomain helicase DNA binding protein 7 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| COL6A1 | collagen, type VI, alpha 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| EPHA4 | EPH receptor A4 |
| FNTB | farnesyltransferase, CAAX box, beta |
| GALK1 | galactokinase 1 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GOLGA2 | golgin A2 |
| GPR137 | G protein-coupled receptor 137 |
| GPR182 | G protein-coupled receptor 182 |
| GPR21 | G protein-coupled receptor 21 |
| GTF2I | general transcription factor IIi |
| HOXA4 | homeobox A4 |
| HRASLS | HRAS-like suppressor |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| ING1 | inhibitor of growth family, member 1 |
| IRF4 | interferon regulatory factor 4 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIF21B | kinesin family member 21B |
| KIF5C | kinesin family member 5C |
| KRT86 | keratin 86, type II |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAMB4 | laminin, beta 4 |
| LHX2 | LIM homeobox 2 |
| LPAR2 | lysophosphatidic acid receptor 2 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MFN2 | mitofusin 2 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MPPE1 | metallophosphoesterase 1 |
| MST1 | macrophage stimulating 1 |
| MVK | mevalonate kinase |
| MYO15A | myosin XVA |
| NBEAL2 | neurobeachin-like 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| ONECUT2 | one cut homeobox 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAGE1 | P antigen family, member 1 (prostate associated) |
| PCBP2 | poly(rC) binding protein 2 |
| PCDH1 | protocadherin 1 |
| PCDH9 | protocadherin 9 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLK3 | polo-like kinase 3 |
| PLSCR4 | phospholipid scramblase 4 |
| POU5F1B | POU class 5 homeobox 1B |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| SDC2 | syndecan 2 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SEPP1 | selenoprotein P, plasma, 1 |
| SH2D3A | SH2 domain containing 3A |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMC1A | structural maintenance of chromosomes 1A |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STK17B | serine/threonine kinase 17b |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TGFA | transforming growth factor, alpha |
| THOC5 | THO complex 5 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM120B | transmembrane protein 120B |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TUBD1 | tubulin, delta 1 |
| VGF | VGF nerve growth factor inducible |
| WWOX | WW domain containing oxidoreductase |
| YY1 | YY1 transcription factor |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| Symbol | Name |
|---|---|
| ALPK1 | alpha-kinase 1 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATP13A2 | ATPase type 13A2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| AURKA | aurora kinase A |
| BCL9 | B-cell CLL/lymphoma 9 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CBX7 | chromobox homolog 7 |
| CCDC69 | coiled-coil domain containing 69 |
| CCNB1 | cyclin B1 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDCA3 | cell division cycle associated 3 |
| CENPE | centromere protein E, 312kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CKAP2 | cytoskeleton associated protein 2 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| COBL | cordon-bleu WH2 repeat protein |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| ERCC2 | excision repair cross-complementation group 2 |
| EXOC5 | exocyst complex component 5 |
| FZD8 | frizzled class receptor 8 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| H1F0 | H1 histone family, member 0 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BC | histone cluster 1, H2bc |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HJURP | Holliday junction recognition protein |
| HMBOX1 | homeobox containing 1 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| KLHL26 | kelch-like family member 26 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MOB3B | MOB kinase activator 3B |
| MYL5 | myosin, light chain 5, regulatory |
| NAIP | NLR family, apoptosis inhibitory protein |
| NARFL | nuclear prelamin A recognition factor-like |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| PLK1 | polo-like kinase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRR15L | proline rich 15-like |
| PRR3 | proline rich 3 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAB5B | RAB5B, member RAS oncogene family |
| RARS | arginyl-tRNA synthetase |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RSBN1 | round spermatid basic protein 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDAD1 | SDA1 domain containing 1 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STX5 | syntaxin 5 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TBL3 | transducin (beta)-like 3 |
| TGFB3 | transforming growth factor, beta 3 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOLLIP | toll interacting protein |
| TRABD | TraB domain containing |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP6NL | USP6 N-terminal like |
| WDR60 | WD repeat domain 60 |
| WDR91 | WD repeat domain 91 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF165 | zinc finger protein 165 |
| ZNF280D | zinc finger protein 280D |
| ZNF551 | zinc finger protein 551 |
| ZNF8 | zinc finger protein 8 |
| ZNF862 | zinc finger protein 862 |
