| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the trifluridine-7176 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit |
| APC | adenomatous polyposis coli |
| ASTN2 | astrotactin 2 |
| ATF6 | activating transcription factor 6 |
| ATM | ATM serine/threonine kinase |
| ATXN2L | ataxin 2-like |
| BTG2 | BTG family, member 2 |
| CARD10 | caspase recruitment domain family, member 10 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCNE2 | cyclin E2 |
| CCNG2 | cyclin G2 |
| CCPG1 | cell cycle progression 1 |
| CD44 | CD44 molecule (Indian blood group) |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DAPK2 | death-associated protein kinase 2 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DTNA | dystrobrevin, alpha |
| EGR1 | early growth response 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ESR1 | estrogen receptor 1 |
| ETV6 | ets variant 6 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM212B | family with sequence similarity 212, member B |
| FAS | Fas cell surface death receptor |
| FBLN1 | fibulin 1 |
| FILIP1L | filamin A interacting protein 1-like |
| FLOT2 | flotillin 2 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GPR87 | G protein-coupled receptor 87 |
| GRM4 | glutamate receptor, metabotropic 4 |
| HFE | hemochromatosis |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| ICAM1 | intercellular adhesion molecule 1 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| ING2 | inhibitor of growth family, member 2 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KLHL22 | kelch-like family member 22 |
| KLHL25 | kelch-like family member 25 |
| LRRC14 | leucine rich repeat containing 14 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYST | lysosomal trafficking regulator |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MALT1 | MALT1 paracaspase |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MXD4 | MAX dimerization protein 4 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF1 | neurofibromin 1 |
| NRSN2 | neurensin 2 |
| OLFML2A | olfactomedin-like 2A |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PROCR | protein C receptor, endothelial |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| QKI | QKI, KH domain containing, RNA binding |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RBM5 | RNA binding motif protein 5 |
| RPL7 | ribosomal protein L7 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SIRPA | signal-regulatory protein alpha |
| SPRR1A | small proline-rich protein 1A |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TEP1 | telomerase-associated protein 1 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| THBD | thrombomodulin |
| TJP3 | tight junction protein 3 |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TREX1 | three prime repair exonuclease 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF280D | zinc finger protein 280D |
| ZNF407 | zinc finger protein 407 |
| ZNF45 | zinc finger protein 45 |
| ZNF747 | zinc finger protein 747 |
| ZNF749 | zinc finger protein 749 |
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APIP | APAF1 interacting protein |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| AURKA | aurora kinase A |
| BCL2L2 | BCL2-like 2 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CCNB1 | cyclin B1 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDCA8 | cell division cycle associated 8 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CENPA | centromere protein A |
| CENPE | centromere protein E, 312kDa |
| CENPT | centromere protein T |
| CEP85 | centrosomal protein 85kDa |
| CEP97 | centrosomal protein 97kDa |
| CHMP6 | charged multivesicular body protein 6 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DEPDC1 | DEP domain containing 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DUSP5 | dual specificity phosphatase 5 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EDC3 | enhancer of mRNA decapping 3 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| FAM192A | family with sequence similarity 192, member A |
| FAM64A | family with sequence similarity 64, member A |
| FANCF | Fanconi anemia, complementation group F |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTPBP2 | GTP binding protein 2 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| H1F0 | H1 histone family, member 0 |
| H1FX | H1 histone family, member X |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| KIF14 | kinesin family member 14 |
| KIF18A | kinesin family member 18A |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| KIFC1 | kinesin family member C1 |
| LMNB1 | lamin B1 |
| LRRC16A | leucine rich repeat containing 16A |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MEIS1 | Meis homeobox 1 |
| METTL21B | methyltransferase like 21B |
| MEX3C | mex-3 RNA binding family member C |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| NBEAL2 | neurobeachin-like 2 |
| NDC80 | NDC80 kinetochore complex component |
| NOL9 | nucleolar protein 9 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PISD | phosphatidylserine decarboxylase |
| PLK1 | polo-like kinase 1 |
| PRC1 | protein regulator of cytokinesis 1 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBM42 | RNA binding motif protein 42 |
| RFX7 | regulatory factor X, 7 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SAV1 | salvador family WW domain containing protein 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SHROOM2 | shroom family member 2 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TESK1 | testis-specific kinase 1 |
| TFB1M | transcription factor B1, mitochondrial |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM104 | transmembrane protein 104 |
| TMEM184B | transmembrane protein 184B |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TPX2 | TPX2, microtubule-associated |
| TRABD | TraB domain containing |
| TRAF2 | TNF receptor-associated factor 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMT61A | tRNA methyltransferase 61A |
| TTK | TTK protein kinase |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZNF165 | zinc finger protein 165 |
| ZNF586 | zinc finger protein 586 |
