triflusal-2867 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the triflusal-2867 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
AKT3 v-akt murine thymoma viral oncogene homolog 3
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APAF1 apoptotic peptidase activating factor 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARR3 arrestin 3, retinal (X-arrestin)
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BHLHE41 basic helix-loop-helix family, member e41
BMP6 bone morphogenetic protein 6
C10ORF95 chromosome 10 open reading frame 95
C19ORF66 chromosome 19 open reading frame 66
C21ORF2 chromosome 21 open reading frame 2
C2ORF27A chromosome 2 open reading frame 27A
CA5B carbonic anhydrase VB, mitochondrial
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CADM4 cell adhesion molecule 4
CAPN2 calpain 2, (m/II) large subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD5L CD5 molecule-like
CD83 CD83 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP41 centrosomal protein 41kDa
CFAP45 cilia and flagella associated protein 45
COL1A2 collagen, type I, alpha 2
CRMP1 collapsin response mediator protein 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAAM2 dishevelled associated activator of morphogenesis 2
DCLK2 doublecortin-like kinase 2
DHRS12 dehydrogenase/reductase (SDR family) member 12
DIRAS2 DIRAS family, GTP-binding RAS-like 2
EFNA5 ephrin-A5
ENO3 enolase 3 (beta, muscle)
ETNK2 ethanolamine kinase 2
FCMR Fc fragment of IgM receptor
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGF21 fibroblast growth factor 21
FGFR2 fibroblast growth factor receptor 2
FSCN1 fascin actin-bundling protein 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GPSM3 G-protein signaling modulator 3
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRPR gastrin-releasing peptide receptor
GSK3A glycogen synthase kinase 3 alpha
GYPB glycophorin B (MNS blood group)
HMGN5 high mobility group nucleosome binding domain 5
HPGDS hematopoietic prostaglandin D synthase
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IL11 interleukin 11
IL1RAP interleukin 1 receptor accessory protein
ING2 inhibitor of growth family, member 2
IRS4 insulin receptor substrate 4
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA0040 KIAA0040
KIAA0368 KIAA0368
KLHL22 kelch-like family member 22
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LMNA lamin A/C
MAGEA5 melanoma antigen family A5
MED25 mediator complex subunit 25
METTL7A methyltransferase like 7A
MSR1 macrophage scavenger receptor 1
NOD1 nucleotide-binding oligomerization domain containing 1
NPTX2 neuronal pentraxin II
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
ODAM odontogenic, ameloblast asssociated
OR7A5 olfactory receptor, family 7, subfamily A, member 5
OSBPL10 oxysterol binding protein-like 10
PDCD6 programmed cell death 6
PGLYRP4 peptidoglycan recognition protein 4
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PYHIN1 pyrin and HIN domain family, member 1
RARA retinoic acid receptor, alpha
RCAN3 RCAN family member 3
RGS5 regulator of G-protein signaling 5
RPL18 ribosomal protein L18
RREB1 ras responsive element binding protein 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDC2 syndecan 2
SLC43A3 solute carrier family 43, member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SSX3 synovial sarcoma, X breakpoint 3
STIM1 stromal interaction molecule 1
TBL2 transducin (beta)-like 2
TLN2 talin 2
TPM3 tropomyosin 3
TREM2 triggering receptor expressed on myeloid cells 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
UTF1 undifferentiated embryonic cell transcription factor 1
WDTC1 WD and tetratricopeptide repeats 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZEB1 zinc finger E-box binding homeobox 1
ZNF552 zinc finger protein 552
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY6 adenylate cyclase 6
ADM adrenomedullin
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARFRP1 ADP-ribosylation factor related protein 1
B9D2 B9 protein domain 2
BCAS1 breast carcinoma amplified sequence 1
C1ORF159 chromosome 1 open reading frame 159
CAPN5 calpain 5
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHPF chondroitin polymerizing factor
CPTP ceramide-1-phosphate transfer protein
CST3 cystatin C
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAL4 dynein, axonemal, light chain 4
EFCAB2 EF-hand calcium binding domain 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
F8 coagulation factor VIII, procoagulant component
FAM46C family with sequence similarity 46, member C
FAN1 FANCD2/FANCI-associated nuclease 1
GEMIN8 gem (nuclear organelle) associated protein 8
GID4 GID complex subunit 4
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPATCH3 G patch domain containing 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIRA histone cell cycle regulator
HOXC10 homeobox C10
HPS5 Hermansky-Pudlak syndrome 5
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNAR1 interferon (alpha, beta and omega) receptor 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM7A lysine (K)-specific demethylase 7A
KLF2 Kruppel-like factor 2
LAMB3 laminin, beta 3
LHX6 LIM homeobox 6
LMBR1L limb development membrane protein 1-like
LOC390998 ribosomal protein L10 pseudogene
LRP5 low density lipoprotein receptor-related protein 5
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MDM4 MDM4, p53 regulator
MGC12488
MPI mannose phosphate isomerase
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MRPL2 mitochondrial ribosomal protein L2
NDRG4 NDRG family member 4
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOL10 nucleolar protein 10
NPIPB3 nuclear pore complex interacting protein family, member B3
OSGIN1 oxidative stress induced growth inhibitor 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARP12 poly (ADP-ribose) polymerase family, member 12
PDZD8 PDZ domain containing 8
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
POMT2 protein-O-mannosyltransferase 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PROS1 protein S (alpha)
PRR7 proline rich 7 (synaptic)
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTPRU protein tyrosine phosphatase, receptor type, U
RASL11B RAS-like, family 11, member B
RNF2 ring finger protein 2
RPGRIP1L RPGRIP1-like
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMAD7 SMAD family member 7
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TK1 thymidine kinase 1, soluble
TMEM180 transmembrane protein 180
TNNT1 troponin T type 1 (skeletal, slow)
TNS2 tensin 2
TRABD TraB domain containing
TRAIP TRAF interacting protein
TRIM36 tripartite motif containing 36
TTC33 tetratricopeptide repeat domain 33
TWISTNB TWIST neighbor
VAV1 vav 1 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZBTB39 zinc finger and BTB domain containing 39
ZNF254 zinc finger protein 254
ZNF280D zinc finger protein 280D
ZNF639 zinc finger protein 639
ZNF747 zinc finger protein 747
ZSCAN2 zinc finger and SCAN domain containing 2