triggered Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

440 genes co-occuring with the biological term triggered in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTG1 actin gamma 1
ACVR1 activin A receptor, type I
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAR adenosine deaminase, RNA-specific
ADCY5 adenylate cyclase 5
ADD1 adducin 1 (alpha)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA3 adenosine A3 receptor
AGER advanced glycosylation end product-specific receptor
AGGF1 angiogenic factor with G patch and FHA domains 1
AICDA activation-induced cytidine deaminase
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALOX5 arachidonate 5-lipoxygenase
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANGPT1 angiopoietin 1
API5 apoptosis inhibitor 5
APLN apelin
APOH apolipoprotein H (beta-2-glycoprotein I)
APOL1 apolipoprotein L, 1
APP amyloid beta (A4) precursor protein
AQP4 aquaporin 4
AR androgen receptor
ARF1 ADP-ribosylation factor 1
ATM ATM serine/threonine kinase
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATR ATR serine/threonine kinase
ATXN2 ataxin 2
AURKB aurora kinase B
AZU1 azurocidin 1
B2M beta-2-microglobulin
BACE1 beta-site APP-cleaving enzyme 1
BAD BCL2-associated agonist of cell death
BAG6 BCL2-associated athanogene 6
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCLAF1 BCL2-associated transcription factor 1
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BGLAP bone gamma-carboxyglutamate (gla) protein
BID BH3 interacting domain death agonist
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BMP7 bone morphogenetic protein 7
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRCA2 breast cancer 2, early onset
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CARTPT CART prepropeptide
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCND2 cyclin D2
CCR2 chemokine (C-C motif) receptor 2
CD163 CD163 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD28 CD28 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD80 CD80 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFLAR CASP8 and FADD-like apoptosis regulator
CHD5 chromodomain helicase DNA binding protein 5
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHIT1 chitinase 1 (chitotriosidase)
CISD1 CDGSH iron sulfur domain 1
CKM creatine kinase, muscle
CLEC7A C-type lectin domain family 7, member A
CLIP3 CAP-GLY domain containing linker protein 3
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNR1 cannabinoid receptor 1 (brain)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREB1 cAMP responsive element binding protein 1
CREB3 cAMP responsive element binding protein 3
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
CYTH2 cytohesin 2
DAXX death-domain associated protein
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEDD death effector domain containing
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DIABLO diablo, IAP-binding mitochondrial protein
DICER1 dicer 1, ribonuclease type III
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNM1L dynamin 1-like
DROSHA drosha, ribonuclease type III
DSP desmoplakin
DUOX2 dual oxidase 2
DYNLT1 dynein, light chain, Tctex-type 1
DYSF dysferlin
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EP300 E1A binding protein p300
EPHB1 EPH receptor B1
ERBB2 erb-b2 receptor tyrosine kinase 2
EREG epiregulin
ESRRA estrogen-related receptor alpha
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXOC1 exocyst complex component 1
EXOC4 exocyst complex component 4
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F9 coagulation factor IX
FANCD2 Fanconi anemia, complementation group D2
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCRL3 Fc receptor-like 3
FERMT3 fermitin family member 3
FGF10 fibroblast growth factor 10
FGF7 fibroblast growth factor 7
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FKBP5 FK506 binding protein 5
FLCN folliculin
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXP1 forkhead box P1
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FSHR follicle stimulating hormone receptor
FUS FUS RNA binding protein
GADD45A growth arrest and DNA-damage-inducible, alpha
GFER growth factor, augmenter of liver regeneration
GHRL ghrelin/obestatin prepropeptide
GLTP glycolipid transfer protein
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLM1 golgi membrane protein 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP6 glycoprotein VI (platelet)
GPER1 G protein-coupled estrogen receptor 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR39 G protein-coupled receptor 39
GPR4 G protein-coupled receptor 4
GRID2 glutamate receptor, ionotropic, delta 2
GRM1 glutamate receptor, metabotropic 1
GSK3B glycogen synthase kinase 3 beta
GZMK granzyme K (granzyme 3; tryptase II)
H2AFX H2A histone family, member X
HBB hemoglobin, beta
HBEGF heparin-binding EGF-like growth factor
HCK HCK proto-oncogene, Src family tyrosine kinase
HCLS1 hematopoietic cell-specific Lyn substrate 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK1 hexokinase 1
HK2 hexokinase 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-G major histocompatibility complex, class I, G
HMGA1 high mobility group AT-hook 1
HMGB1 high mobility group box 1
HPCA hippocalcin
HRC histidine rich calcium binding protein
HTN3 histatin 3
HTRA2 HtrA serine peptidase 2
HTT huntingtin
ICOSLG inducible T-cell co-stimulator ligand
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGFBP3 insulin-like growth factor binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL20 interleukin 20
IL27 interleukin 27
IL33 interleukin 33
IL4 interleukin 4
IL6 interleukin 6
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
IQGAP1 IQ motif containing GTPase activating protein 1
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
IRS1 insulin receptor substrate 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
ITGB6 integrin, beta 6
ITGB8 integrin, beta 8
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAG1 jagged 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KARS lysyl-tRNA synthetase
KAT2B K(lysine) acetyltransferase 2B
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCTD8 potassium channel tetramerization domain containing 8
KMT2A lysine (K)-specific methyltransferase 2A
KRIT1 KRIT1, ankyrin repeat containing
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS8 lectin, galactoside-binding, soluble, 8
LMNA lamin A/C
LRP1 low density lipoprotein receptor-related protein 1
LRRK1 leucine-rich repeat kinase 1
LTA lymphotoxin alpha
LY6D lymphocyte antigen 6 complex, locus D
LYN LYN proto-oncogene, Src family tyrosine kinase
MACC1 metastasis associated in colon cancer 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K15 mitogen-activated protein kinase kinase kinase 15
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP4 microtubule-associated protein 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MCL1 myeloid cell leukemia 1
MCM10 minichromosome maintenance complex component 10
MECP2 methyl CpG binding protein 2
MEF2A myocyte enhancer factor 2A
MEF2B myocyte enhancer factor 2B
MEF2C myocyte enhancer factor 2C
MEP1A meprin A, alpha (PABA peptide hydrolase)
MET MET proto-oncogene, receptor tyrosine kinase
MICA MHC class I polypeptide-related sequence A
MIR101-1 microRNA 101-1
MIR145 microRNA 145
MIR210 microRNA 210
MIR29B1 microRNA 29b-1
MIR449A microRNA 449a
MIR451A microRNA 451a
MIR548M microRNA 548m
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLXIP MLX interacting protein
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MTMR3 myotubularin related protein 3
MUC2 mucin 2, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYOG myogenin (myogenic factor 4)
NBN nibrin
NCR3 natural cytotoxicity triggering receptor 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOTCH1 notch 1
NOTCH3 notch 3
NOV nephroblastoma overexpressed
NPC1 Niemann-Pick disease, type C1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTS neurotensin
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OTC ornithine carbamoyltransferase
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PARK2 parkin RBR E3 ubiquitin protein ligase
PCDH19 protocadherin 19
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PINK1 PTEN induced putative kinase 1
PLG plasminogen
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PNLIP pancreatic lipase
PNPLA3 patatin-like phospholipase domain containing 3
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP4R1 protein phosphatase 4, regulatory subunit 1
PRDX3 peroxiredoxin 3
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRLR prolactin receptor
PRMT1 protein arginine methyltransferase 1
PSEN1 presenilin 1
PTN pleiotrophin
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB4A RAB4A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RB1 retinoblastoma 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
REST RE1-silencing transcription factor
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RHO rhodopsin
RHOA ras homolog family member A
RNASE3 ribonuclease, RNase A family, 3
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
ROMO1 reactive oxygen species modulator 1
RTL1 retrotransposon-like 1
RUSC2 RUN and SH3 domain containing 2
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAR1A secretion associated, Ras related GTPase 1A
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SENP1 SUMO1/sentrin specific peptidase 1
SFRP1 secreted frizzled-related protein 1
SH2B3 SH2B adaptor protein 3
SIRT1 sirtuin 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD2 SMAD family member 2
SMC1A structural maintenance of chromosomes 1A
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SNAI2 snail family zinc finger 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SP1 Sp1 transcription factor
SPHK1 sphingosine kinase 1
SQSTM1 sequestosome 1
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRI sorcin
SSH2 slingshot protein phosphatase 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STAU1 staufen double-stranded RNA binding protein 1
STIL SCL/TAL1 interrupting locus
STIM1 stromal interaction molecule 1
STPG1 sperm-tail PG-rich repeat containing 1
SYK spleen tyrosine kinase
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TACR1 tachykinin receptor 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TFE3 transcription factor binding to IGHM enhancer 3
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TMEM173 transmembrane protein 173
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TRA T cell receptor alpha locus
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIP13 thyroid hormone receptor interactor 13
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSC2 tuberous sclerosis 2
TXNIP thioredoxin interacting protein
ULK1 unc-51 like autophagy activating kinase 1
USP18 ubiquitin specific peptidase 18
USP2 ubiquitin specific peptidase 2
VAV1 vav 1 guanine nucleotide exchange factor
VCAN versican
VDAC1 voltage-dependent anion channel 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YAP1 Yes-associated protein 1
ZBP1 Z-DNA binding protein 1